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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P02679 SWISS-2DPAGE:  P02679 P02679 General information about the entry View entry in simple text format Entry name FIBG_HUMAN Primary accession number P02679 integrated into SWISS-2DPAGE on  August 1, 1993 (release 0) 2D Annotations were last modified on March 31, 2004 (version 1) General Annotations were last modified on  May 19, 2011 (version 16) Name and origin of the protein Description RecName: Full=Fibrinogen gamma chain; Flags: Precursor;. Gene name Name=FGG ORFNames=PRO2061 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan] Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F. ''''''Inside SWISS-2DPAGE database'';'';'' Electrophoresis 16(1):1131-1151(1995) [2]   MAPPING ON GEL MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan] Anderson N.L., Anderson N.G. ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'' Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977) 2D PAGE maps for identified proteins How to interpret a protein CSF_HUMAN {Cerebrospinal Fluid} Homo sapiens (Human) Tissue: Cerebrospinal fluid   map experimental info   protein estimated location   CSF_HUMAN MAP LOCATIONS: SPOT 2D-000BYX: pI=5.45; Mw=51657 SPOT 2D-000BYY: pI=5.53; Mw=51526 SPOT 2D-000BZ6: pI=5.59; Mw=51395 MAPPING (identification): MATCHING WITH THE PLASMA MASTER GEL [1]. HEPG2SP_HUMAN {HepG2 Secreted Proteins} Homo sapiens (Human) Tissue: Hepatoblastoma   map experimental info   protein estimated location   HEPG2SP_HUMAN MAP LOCATIONS: SPOT 2D-00091S: pI=5.30; Mw=46128 SPOT 2D-00091T: pI=5.38; Mw=45977 SPOT 2D-00091V: pI=5.45; Mw=45977 MAPPING (identification): MATCHING WITH THE PLASMA MASTER GEL [1]. PLASMA_HUMAN {Plasma} Homo sapiens (Human) Tissue: Plasma   map experimental info   protein estimated location   PLASMA_HUMAN MAP LOCATIONS: SPOT 2D-0004VN: pI=5.07; Mw=51347 SPOT 2D-0004VU: pI=5.03; Mw=51347 SPOT 2D-0004VY: pI=5.13; Mw=51207 SPOT 2D-0004VZ: pI=5.16; Mw=51068 SPOT 2D-0004WN: pI=5.44; Mw=49431 SPOT 2D-0004WQ: pI=5.34; Mw=49566 SPOT 2D-0004WR: pI=5.56; Mw=49431 SPOT 2D-0004WT: pI=5.24; Mw=49566 SPOT 2D-0004WU: pI=5.65; Mw=49566 SPOT 2D-0004XS: pI=5.44; Mw=48107 SPOT 2D-0004XV: pI=5.56; Mw=48107 SPOT 2D-0004ZZ: pI=5.56; Mw=44585 SPOT 2D-000500: pI=5.62; Mw=44707 MAPPING (identification): MATCHING WITH THE ANDERSON'S PLASMA MAP [2]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P02679; P02679. DOSAC-COBS-2DPAGE P02679; FIBG_HUMAN. OGP-WWW P02679. REPRODUCTION-2DPAGE P02679; P02679. REPRODUCTION-2DPAGE IPI00219713; IPI00219713. Siena-2DPAGE P02679; FIBG_HUMAN. UniProtKB/Swiss-Prot P02679; FIBG_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name FIBG_HUMAN Primary accession number P02679 Secondary accession number(s) A8K057 P04469 P04470 Q53Y18 Q96A14 Q96KJ3 Q9UC62 Q9UC63 Q9UCF3 Sequence was last modified on  April 16, 2002 (version 3) Annotations were last modified on  September 21, 2011 (version 158) Name and origin of the protein Description RecName: Full=Fibrinogen gamma chain; Flags: Precursor; Gene name Name=FGG ORFNames=PRO2061 Encoded on Name=FGG; ORFNames=PRO2061 Keywords 3D-structure; Alternative splicing; Blood coagulation; Calcium; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Disulfide bond; Glycoprotein; Isopeptide bond; Polymorphism; Reference proteome; Secreted; Signal; Sulfation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M10014; AAB59530.1; -; Genomic_DNA EMBL M10014; AAB59531.1; -; Genomic_DNA EMBL AF118092; AAF22036.1; -; mRNA EMBL AF350254; AAK19751.2; -; Genomic_DNA EMBL AF350254; AAK19752.2; -; Genomic_DNA EMBL AK289422; BAF82111.1; -; mRNA EMBL AK290824; BAF83513.1; -; mRNA EMBL BT007081; AAP35744.1; -; mRNA EMBL CH471056; EAX04917.1; -; Genomic_DNA EMBL CH471056; EAX04919.1; -; Genomic_DNA EMBL BC007044; AAH07044.1; -; mRNA EMBL BC021674; AAH21674.1; -; mRNA EMBL X51473; CAA35837.1; -; mRNA EMBL X00086; CAA24944.1; -; mRNA EMBL K02569; AAA52430.1; -; Genomic_DNA EMBL K02569; AAA52431.1; -; Genomic_DNA IPI IPI00021891; -; . IPI IPI00219713; -; . PIR A90470; FGHUG; . PIR A90494; FGHUGB; . RefSeq NP_000500.2; NM_000509.4; . RefSeq NP_068656.2; NM_021870.2; . UniGene Hs.713625; -; . PDB 1DUG; X-ray; 1.80 A; A/B=424-433 PDB 1FIB; X-ray; 2.10 A; A=169-433 PDB 1FIC; X-ray; 2.50 A; A/B=169-433 PDB 1FID; X-ray; 2.10 A; A=169-433 PDB 1FZA; X-ray; 2.90 A; C/F=114-432 PDB 1FZB; X-ray; 2.90 A; C/F=114-432 PDB 1FZC; X-ray; 2.30 A; C/F=114-432 PDB 1FZE; X-ray; 3.00 A; C/F=114-432 PDB 1FZF; X-ray; 2.70 A; C/F=114-432 PDB 1FZG; X-ray; 2.50 A; C/F=114-432 PDB 1LT9; X-ray; 2.80 A; C/F=122-432 PDB 1LTJ; X-ray; 2.80 A; C/F=122-432 PDB 1N86; X-ray; 3.20 A; C/F=114-433 PDB 1N8E; X-ray; 4.50 A; C/F=114-433 PDB 1RE3; X-ray; 2.45 A; C/F=122-432 PDB 1RE4; X-ray; 2.70 A; C/F=122-432 PDB 1RF0; X-ray; 2.81 A; C/F=122-432 PDB 1RF1; X-ray; 2.53 A; C/F=122-432 PDB 2A45; X-ray; 3.65 A; I/L=27-71 PDB 2FFD; X-ray; 2.89 A; C/F=122-432 PDB 2FIB; X-ray; 2.01 A; A=169-433 PDB 2H43; X-ray; 2.70 A; C/F=115-433 PDB 2HLO; X-ray; 2.60 A; C/F=114-433 PDB 2HOD; X-ray; 2.90 A; C/F/I/L=115-433 PDB 2HPC; X-ray; 2.90 A; C/F/I/L=115-433 PDB 2HWL; X-ray; 2.40 A; P=439-452 PDB 2OYH; X-ray; 2.40 A; C/F=122-432 PDB 2OYI; X-ray; 2.70 A; C/F=122-432 PDB 2Q9I; X-ray; 2.80 A; C/F=114-433 PDB 2VDO; X-ray; 2.51 A; C=426-433 PDB 2VDP; X-ray; 2.80 A; C=428-433 PDB 2VDQ; X-ray; 2.59 A; C=426-433 PDB 2VDR; X-ray; 2.40 A; C=428-433 PDB 2VR3; X-ray; 1.95 A; C/D=425-433 PDB 2XNX; X-ray; 3.30 A; C/F/I/L=114-432 PDB 2XNY; X-ray; 7.50 A; C/F=114-432 PDB 2Z4E; X-ray; 2.70 A; C/F=114-433 PDB 3BVH; X-ray; 2.60 A; C/F=128-420 PDB 3E1I; X-ray; 2.30 A; C/F=114-432 PDB 3FIB; X-ray; 2.10 A; A=170-418 PDB 3GHG; X-ray; 2.90 A; C/F/I/L=27-433 PDB 3H32; X-ray; 3.60 A; C/F=121-433 PDB 3HUS; X-ray; 3.04 A; C/F=122-432 PDBsum 1DUG; -; . PDBsum 1FIB; -; . PDBsum 1FIC; -; . PDBsum 1FID; -; . PDBsum 1FZA; -; . PDBsum 1FZB; -; . PDBsum 1FZC; -; . PDBsum 1FZE; -; . PDBsum 1FZF; -; . PDBsum 1FZG; -; . PDBsum 1LT9; -; . PDBsum 1LTJ; -; . PDBsum 1N86; -; . PDBsum 1N8E; -; . PDBsum 1RE3; -; . PDBsum 1RE4; -; . PDBsum 1RF0; -; . PDBsum 1RF1; -; . PDBsum 2A45; -; . PDBsum 2FFD; -; . PDBsum 2FIB; -; . PDBsum 2H43; -; . PDBsum 2HLO; -; . PDBsum 2HOD; -; . PDBsum 2HPC; -; . PDBsum 2HWL; -; . PDBsum 2OYH; -; . PDBsum 2OYI; -; . PDBsum 2Q9I; -; . PDBsum 2VDO; -; . PDBsum 2VDP; -; . PDBsum 2VDQ; -; . PDBsum 2VDR; -; . PDBsum 2VR3; -; . PDBsum 2XNX; -; . PDBsum 2XNY; -; . PDBsum 2Z4E; -; . PDBsum 3BVH; -; . PDBsum 3E1I; -; . PDBsum 3FIB; -; . PDBsum 3GHG; -; . PDBsum 3H32; -; . PDBsum 3HUS; -; . ProteinModelPortal P02679; -; . SMR P02679; 28-421; . DIP DIP-29644N; -; . IntAct P02679; 1; . STRING P02679; -; . SWISS-2DPAGE P02679; -; . Cornea-2DPAGE P02679; -; . DOSAC-COBS-2DPAGE P02679; -; . OGP P02679; -; . REPRODUCTION-2DPAGE IPI00219713; -; . REPRODUCTION-2DPAGE P02679; -; . Siena-2DPAGE P02679; -; . PeptideAtlas P02679; -; . PRIDE P02679; -; . Ensembl ENST00000336098; ENSP00000336829; ENSG00000171557; . GeneID 2266; -; . KEGG hsa:2266; -; . UCSC uc003ioj.1; human; . CTD 2266; -; . GeneCards GC04M151265; -; . HGNC HGNC:3694; FGG; . HPA HPA027529; -; . MIM 134850; gene; . MIM 202400; phenotype; . neXtProt NX_P02679; -; . Orphanet 98880; Familial afibrinogenemia; . Orphanet 98881; Familial dysfibrinogenemia; . Orphanet 248408; Familial hypodysfibrinogenemia; . Orphanet 101041; Familial hypofibrinogenemia; . PharmGKB PA430; -; . eggNOG prNOG14762; -; . GeneTree ENSGT00600000084261; -; . HOVERGEN HBG099783; -; . PhylomeDB P02679; -; . Pathway_Interaction_DB il6_7pathway; IL6-mediated signaling events; . Reactome REACT_13552; Integrin cell surface interactions; . Reactome REACT_604; Hemostasis; . DrugBank DB00364; Sucralfate; . NextBio 9205; -; . PMAP-CutDB P02679; -; . ArrayExpress P02679; -; . Bgee P02679; -; . CleanEx HS_FGG; -; . Genevestigator P02679; -; . GermOnline ENSG00000171557; Homo sapiens; . GO GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL; . GO GO:0005577; C:fibrinogen complex; TAS:ProtInc; . GO GO:0031093; C:platelet alpha granule lumen; TAS:Reactome; . GO GO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL; . GO GO:0030674; F:protein binding; bridging; IEA:InterPro GO GO:0005102; F:receptor binding; IEA:InterPro; . GO GO:0030168; P:platelet activation; TAS:Reactome; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0051258; P:protein polymerization; IEA:InterPro; . GO GO:0051592; P:response to calcium ion; IDA:BHF-UCL; . GO GO:0007165; P:signal transduction; IEA:InterPro; . InterPro IPR002181; Fibrinogen_a/b/g_C; . InterPro IPR014716; Fibrinogen_a/b/g_C_1; . InterPro IPR014715; Fibrinogen_a/b/g_C_2; . InterPro IPR012290; Fibrinogen_a/b/g_coil_dom; . InterPro IPR020837; Fibrinogen_CS; . Gene3D G3DSA:3.90.215.10; Fibrinogen_a/b/g_C_1; 1; . Gene3D G3DSA:4.10.530.10; Fibrinogen_a/b/g_C_2; 1; . Gene3D G3DSA:1.20.5.50; Fibrinogen_a/b/g_coil; 1; . Pfam PF08702; Fib_alpha; 1; . Pfam PF00147; Fibrinogen_C; 1; . SMART SM00186; FBG; 1; . SUPFAM SSF56496; Fibrinogen_a/b/g_C; 1; . PROSITE PS00514; FIBRINOGEN_C_1; 1; . PROSITE PS51406; FIBRINOGEN_C_2; 1; . SWISS-2DPAGE (search AC)