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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P02679




SWISS-2DPAGE:  P02679


P02679


General information about the entry
View entry in simple text format
Entry nameFIBG_HUMAN
Primary accession numberP02679
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 16)
Name and origin of the protein
DescriptionRecName: Full=Fibrinogen gamma chain; Flags: Precursor;.
Gene nameName=FGG
ORFNames=PRO2061
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
[2]   MAPPING ON GEL
MEDLINE=78094420; PubMed=271964; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Anderson N.G.
''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';''
Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977)
2D PAGE maps for identified proteins
How to interpret a protein

CSF_HUMAN {Cerebrospinal Fluid}
Homo sapiens (Human)
Tissue: Cerebrospinal fluid
CSF_HUMAN
  map experimental info
  protein estimated location
 
CSF_HUMAN

MAP LOCATIONS:
pI=5.45; Mw=51657
pI=5.53; Mw=51526
pI=5.59; Mw=51395

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [1].



HEPG2SP_HUMAN {HepG2 Secreted Proteins}
Homo sapiens (Human)
Tissue: Hepatoblastoma
HEPG2SP_HUMAN
  map experimental info
  protein estimated location
 
HEPG2SP_HUMAN

MAP LOCATIONS:
pI=5.30; Mw=46128
pI=5.38; Mw=45977
pI=5.45; Mw=45977

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [1].



PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=5.07; Mw=51347
pI=5.03; Mw=51347
pI=5.13; Mw=51207
pI=5.16; Mw=51068
pI=5.44; Mw=49431
pI=5.34; Mw=49566
pI=5.56; Mw=49431
pI=5.24; Mw=49566
pI=5.65; Mw=49566
pI=5.44; Mw=48107
pI=5.56; Mw=48107
pI=5.56; Mw=44585
pI=5.62; Mw=44707

MAPPING (identification):
MATCHING WITH THE ANDERSON'S PLASMA MAP [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP02679; P02679.
DOSAC-COBS-2DPAGEP02679; FIBG_HUMAN.
OGP-WWWP02679.
REPRODUCTION-2DPAGEP02679; P02679.
REPRODUCTION-2DPAGEIPI00219713; IPI00219713.
Siena-2DPAGEP02679; FIBG_HUMAN.
UniProtKB/Swiss-ProtP02679; FIBG_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameFIBG_HUMAN
Primary accession numberP02679
Secondary accession number(s) A8K057 P04469 P04470 Q53Y18 Q96A14 Q96KJ3 Q9UC62 Q9UC63 Q9UCF3
Sequence was last modified on April 16, 2002 (version 3)
Annotations were last modified on September 21, 2011 (version 158)
Name and origin of the protein
DescriptionRecName: Full=Fibrinogen gamma chain; Flags: Precursor;
Gene nameName=FGG
ORFNames=PRO2061
Encoded onName=FGG; ORFNames=PRO2061
Keywords3D-structure; Alternative splicing; Blood coagulation; Calcium; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Disulfide bond; Glycoprotein; Isopeptide bond; Polymorphism; Reference proteome; Secreted; Signal; Sulfation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM10014; AAB59530.1; -; Genomic_DNA
EMBLM10014; AAB59531.1; -; Genomic_DNA
EMBLAF118092; AAF22036.1; -; mRNA
EMBLAF350254; AAK19751.2; -; Genomic_DNA
EMBLAF350254; AAK19752.2; -; Genomic_DNA
EMBLAK289422; BAF82111.1; -; mRNA
EMBLAK290824; BAF83513.1; -; mRNA
EMBLBT007081; AAP35744.1; -; mRNA
EMBLCH471056; EAX04917.1; -; Genomic_DNA
EMBLCH471056; EAX04919.1; -; Genomic_DNA
EMBLBC007044; AAH07044.1; -; mRNA
EMBLBC021674; AAH21674.1; -; mRNA
EMBLX51473; CAA35837.1; -; mRNA
EMBLX00086; CAA24944.1; -; mRNA
EMBLK02569; AAA52430.1; -; Genomic_DNA
EMBLK02569; AAA52431.1; -; Genomic_DNA
IPIIPI00021891; -; .
IPIIPI00219713; -; .
PIRA90470; FGHUG; .
PIRA90494; FGHUGB; .
RefSeqNP_000500.2; NM_000509.4; .
RefSeqNP_068656.2; NM_021870.2; .
UniGeneHs.713625; -; .
PDB1DUG; X-ray; 1.80 A; A/B=424-433
PDB1FIB; X-ray; 2.10 A; A=169-433
PDB1FIC; X-ray; 2.50 A; A/B=169-433
PDB1FID; X-ray; 2.10 A; A=169-433
PDB1FZA; X-ray; 2.90 A; C/F=114-432
PDB1FZB; X-ray; 2.90 A; C/F=114-432
PDB1FZC; X-ray; 2.30 A; C/F=114-432
PDB1FZE; X-ray; 3.00 A; C/F=114-432
PDB1FZF; X-ray; 2.70 A; C/F=114-432
PDB1FZG; X-ray; 2.50 A; C/F=114-432
PDB1LT9; X-ray; 2.80 A; C/F=122-432
PDB1LTJ; X-ray; 2.80 A; C/F=122-432
PDB1N86; X-ray; 3.20 A; C/F=114-433
PDB1N8E; X-ray; 4.50 A; C/F=114-433
PDB1RE3; X-ray; 2.45 A; C/F=122-432
PDB1RE4; X-ray; 2.70 A; C/F=122-432
PDB1RF0; X-ray; 2.81 A; C/F=122-432
PDB1RF1; X-ray; 2.53 A; C/F=122-432
PDB2A45; X-ray; 3.65 A; I/L=27-71
PDB2FFD; X-ray; 2.89 A; C/F=122-432
PDB2FIB; X-ray; 2.01 A; A=169-433
PDB2H43; X-ray; 2.70 A; C/F=115-433
PDB2HLO; X-ray; 2.60 A; C/F=114-433
PDB2HOD; X-ray; 2.90 A; C/F/I/L=115-433
PDB2HPC; X-ray; 2.90 A; C/F/I/L=115-433
PDB2HWL; X-ray; 2.40 A; P=439-452
PDB2OYH; X-ray; 2.40 A; C/F=122-432
PDB2OYI; X-ray; 2.70 A; C/F=122-432
PDB2Q9I; X-ray; 2.80 A; C/F=114-433
PDB2VDO; X-ray; 2.51 A; C=426-433
PDB2VDP; X-ray; 2.80 A; C=428-433
PDB2VDQ; X-ray; 2.59 A; C=426-433
PDB2VDR; X-ray; 2.40 A; C=428-433
PDB2VR3; X-ray; 1.95 A; C/D=425-433
PDB2XNX; X-ray; 3.30 A; C/F/I/L=114-432
PDB2XNY; X-ray; 7.50 A; C/F=114-432
PDB2Z4E; X-ray; 2.70 A; C/F=114-433
PDB3BVH; X-ray; 2.60 A; C/F=128-420
PDB3E1I; X-ray; 2.30 A; C/F=114-432
PDB3FIB; X-ray; 2.10 A; A=170-418
PDB3GHG; X-ray; 2.90 A; C/F/I/L=27-433
PDB3H32; X-ray; 3.60 A; C/F=121-433
PDB3HUS; X-ray; 3.04 A; C/F=122-432
PDBsum1DUG; -; .
PDBsum1FIB; -; .
PDBsum1FIC; -; .
PDBsum1FID; -; .
PDBsum1FZA; -; .
PDBsum1FZB; -; .
PDBsum1FZC; -; .
PDBsum1FZE; -; .
PDBsum1FZF; -; .
PDBsum1FZG; -; .
PDBsum1LT9; -; .
PDBsum1LTJ; -; .
PDBsum1N86; -; .
PDBsum1N8E; -; .
PDBsum1RE3; -; .
PDBsum1RE4; -; .
PDBsum1RF0; -; .
PDBsum1RF1; -; .
PDBsum2A45; -; .
PDBsum2FFD; -; .
PDBsum2FIB; -; .
PDBsum2H43; -; .
PDBsum2HLO; -; .
PDBsum2HOD; -; .
PDBsum2HPC; -; .
PDBsum2HWL; -; .
PDBsum2OYH; -; .
PDBsum2OYI; -; .
PDBsum2Q9I; -; .
PDBsum2VDO; -; .
PDBsum2VDP; -; .
PDBsum2VDQ; -; .
PDBsum2VDR; -; .
PDBsum2VR3; -; .
PDBsum2XNX; -; .
PDBsum2XNY; -; .
PDBsum2Z4E; -; .
PDBsum3BVH; -; .
PDBsum3E1I; -; .
PDBsum3FIB; -; .
PDBsum3GHG; -; .
PDBsum3H32; -; .
PDBsum3HUS; -; .
ProteinModelPortalP02679; -; .
SMRP02679; 28-421; .
DIPDIP-29644N; -; .
IntActP02679; 1; .
STRINGP02679; -; .
SWISS-2DPAGEP02679; -; .
Cornea-2DPAGEP02679; -; .
DOSAC-COBS-2DPAGEP02679; -; .
OGPP02679; -; .
REPRODUCTION-2DPAGEIPI00219713; -; .
REPRODUCTION-2DPAGEP02679; -; .
Siena-2DPAGEP02679; -; .
PeptideAtlasP02679; -; .
PRIDEP02679; -; .
EnsemblENST00000336098; ENSP00000336829; ENSG00000171557; .
GeneID2266; -; .
KEGGhsa:2266; -; .
UCSCuc003ioj.1; human; .
CTD2266; -; .
GeneCardsGC04M151265; -; .
HGNCHGNC:3694; FGG; .
HPAHPA027529; -; .
MIM134850; gene; .
MIM202400; phenotype; .
neXtProtNX_P02679; -; .
Orphanet98880; Familial afibrinogenemia; .
Orphanet98881; Familial dysfibrinogenemia; .
Orphanet248408; Familial hypodysfibrinogenemia; .
Orphanet101041; Familial hypofibrinogenemia; .
PharmGKBPA430; -; .
eggNOGprNOG14762; -; .
GeneTreeENSGT00600000084261; -; .
HOVERGENHBG099783; -; .
PhylomeDBP02679; -; .
Pathway_Interaction_DBil6_7pathway; IL6-mediated signaling events; .
ReactomeREACT_13552; Integrin cell surface interactions; .
ReactomeREACT_604; Hemostasis; .
DrugBankDB00364; Sucralfate; .
NextBio9205; -; .
PMAP-CutDBP02679; -; .
ArrayExpressP02679; -; .
BgeeP02679; -; .
CleanExHS_FGG; -; .
GenevestigatorP02679; -; .
GermOnlineENSG00000171557; Homo sapiens; .
GOGO:0009897; C:external side of plasma membrane; IDA:BHF-UCL; .
GOGO:0005577; C:fibrinogen complex; TAS:ProtInc; .
GOGO:0031093; C:platelet alpha granule lumen; TAS:Reactome; .
GOGO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL; .
GOGO:0030674; F:protein binding; bridging; IEA:InterPro
GOGO:0005102; F:receptor binding; IEA:InterPro; .
GOGO:0030168; P:platelet activation; TAS:Reactome; .
GOGO:0002576; P:platelet degranulation; TAS:Reactome; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
GOGO:0051592; P:response to calcium ion; IDA:BHF-UCL; .
GOGO:0007165; P:signal transduction; IEA:InterPro; .
InterProIPR002181; Fibrinogen_a/b/g_C; .
InterProIPR014716; Fibrinogen_a/b/g_C_1; .
InterProIPR014715; Fibrinogen_a/b/g_C_2; .
InterProIPR012290; Fibrinogen_a/b/g_coil_dom; .
InterProIPR020837; Fibrinogen_CS; .
Gene3DG3DSA:3.90.215.10; Fibrinogen_a/b/g_C_1; 1; .
Gene3DG3DSA:4.10.530.10; Fibrinogen_a/b/g_C_2; 1; .
Gene3DG3DSA:1.20.5.50; Fibrinogen_a/b/g_coil; 1; .
PfamPF08702; Fib_alpha; 1; .
PfamPF00147; Fibrinogen_C; 1; .
SMARTSM00186; FBG; 1; .
SUPFAMSSF56496; Fibrinogen_a/b/g_C; 1; .
PROSITEPS00514; FIBRINOGEN_C_1; 1; .
PROSITEPS51406; FIBRINOGEN_C_2; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server