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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P04075 SWISS-2DPAGE:  P04075 P04075 General information about the entry View entry in simple text format Entry name ALDOA_HUMAN Primary accession number P04075 integrated into SWISS-2DPAGE on  March 31, 2004 (release 17) 2D Annotations were last modified on March 31, 2004 (version 1) General Annotations were last modified on  May 19, 2011 (version 5) Name and origin of the protein Description RecName: Full=Fructose-bisphosphate aldolase A; EC=4.1.2.13; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase;. Gene name Name=ALDOA Synonyms=ALDA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D. ''''''New insights into HIV lymphocyte infection'';'';'' (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004) Comments SUBUNIT: Homotetramer 2D PAGE maps for identified proteins How to interpret a protein LYMPHOCYTE_HUMAN {Lymphocytes} Homo sapiens (Human) Tissue: Lymphocyte   map experimental info   protein estimated location   LYMPHOCYTE_HUMAN MAP LOCATIONS: SPOT 2D-001Y7K: pI=7.89; Mw=37732   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P04075; P04075. DOSAC-COBS-2DPAGE P04075; ALDOA_HUMAN. OGP-WWW P04075. REPRODUCTION-2DPAGE P04075; P04075. REPRODUCTION-2DPAGE IPI00465439; IPI00465439. Siena-2DPAGE P04075; ALDOA_HUMAN. UCD-2DPAGE P04075; ALDOA_HUMAN. UniProtKB/Swiss-Prot P04075; ALDOA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name ALDOA_HUMAN Primary accession number P04075 Secondary accession number(s) B4DXI7 Q6FH76 Q6FI10 Q96B15 Q9BWD9 Q9UCN2 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  October 19, 2011 (version 146) Name and origin of the protein Description RecName: Full=Fructose-bisphosphate aldolase A; EC=4.1.2.13; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase; Gene name Name=ALDOA Synonyms=ALDA Encoded on Name=ALDOA; Synonyms=ALDA Keywords 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Disease mutation; Glycogen storage disease; Glycolysis; Hereditary hemolytic anemia; Lyase; Phosphoprotein; Polymorphism; Reference proteome; Schiff base. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M11560; AAA51690.1; -; mRNA EMBL X05236; CAA28861.1; -; mRNA EMBL X12447; CAA30979.1; ALT_SEQ; Genomic_DNA EMBL AK301993; BAG63399.1; ALT_INIT; mRNA EMBL CR536528; CAG38765.1; -; mRNA EMBL CR541880; CAG46678.1; -; mRNA EMBL CH471238; EAW79933.1; -; Genomic_DNA EMBL BC000367; AAH00367.2; -; mRNA EMBL BC004333; AAH04333.1; -; mRNA EMBL BC010660; AAH10660.1; -; mRNA EMBL BC012880; AAH12880.1; -; mRNA EMBL BC013614; AAH13614.1; -; mRNA EMBL BC015888; AAH15888.1; -; mRNA EMBL BC016170; AAH16170.1; -; mRNA EMBL BC016800; AAH16800.1; -; mRNA EMBL M21190; AAA51697.1; -; mRNA IPI IPI00465439; -; . PIR S14084; ADHUA; . RefSeq NP_000025.1; NM_000034.3; . RefSeq NP_001121089.1; NM_001127617.2; . RefSeq NP_001230106.1; NM_001243177.1; . RefSeq NP_908930.1; NM_184041.2; . RefSeq NP_908932.1; NM_184043.2; . UniGene Hs.513490; -; . PDB 1ALD; X-ray; 2.00 A; A=2-364 PDB 2ALD; X-ray; 2.10 A; A=2-364 PDB 4ALD; X-ray; 2.80 A; A=2-364 PDBsum 1ALD; -; . PDBsum 2ALD; -; . PDBsum 4ALD; -; . ProteinModelPortal P04075; -; . SMR P04075; 2-364; . IntAct P04075; 11; . MINT MINT-4998828; -; . STRING P04075; -; . PhosphoSite P04075; -; . SWISS-2DPAGE P04075; -; . Aarhus/Ghent-2DPAGE 1302; NEPHGE; . DOSAC-COBS-2DPAGE P04075; -; . OGP P04075; -; . REPRODUCTION-2DPAGE IPI00465439; -; . REPRODUCTION-2DPAGE P04075; -; . Siena-2DPAGE P04075; -; . UCD-2DPAGE P04075; -; . PRIDE P04075; -; . Ensembl ENST00000338110; ENSP00000336927; ENSG00000149925; . Ensembl ENST00000395240; ENSP00000378661; ENSG00000149925; . Ensembl ENST00000395248; ENSP00000378669; ENSG00000149925; . Ensembl ENST00000412304; ENSP00000400452; ENSG00000149925; . Ensembl ENST00000436540; ENSP00000387793; ENSG00000149925; . GeneID 226; -; . KEGG hsa:226; -; . UCSC uc002dvw.1; human; . CTD 226; -; . GeneCards GC16P027726; -; . H-InvDB HIX0012935; -; . HGNC HGNC:414; ALDOA; . HPA CAB006252; -; . HPA HPA004177; -; . MIM 103850; gene; . MIM 611881; phenotype; . neXtProt NX_P04075; -; . Orphanet 57; Aldolase A deficiency; . PharmGKB PA24707; -; . eggNOG prNOG06512; -; . GeneTree ENSGT00390000010235; -; . HOVERGEN HBG002386; -; . InParanoid P04075; -; . OrthoDB EOG4X3H1J; -; . PhylomeDB P04075; -; . BioCyc MetaCyc:HS07647-MONOMER; -; . Pathway_Interaction_DB hif1_tfpathway; HIF-1-alpha transcription factor network; . Reactome REACT_474; Metabolism of carbohydrates; . Reactome REACT_604; Hemostasis; . NextBio 920; -; . ArrayExpress P04075; -; . Bgee P04075; -; . CleanEx HS_ALDOA; -; . Genevestigator P04075; -; . GermOnline ENSG00000149925; Homo sapiens; . GO GO:0015629; C:actin cytoskeleton; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular vesicular exosome; IDA:BHF-UCL; . GO GO:0031674; C:I band; TAS:BHF-UCL; . GO GO:0031093; C:platelet alpha granule lumen; TAS:Reactome; . GO GO:0003779; F:actin binding; TAS:BHF-UCL; . GO GO:0070061; F:fructose binding; IDA:BHF-UCL; . GO GO:0004332; F:fructose-bisphosphate aldolase activity; IDA:BHF-UCL; . GO GO:0042802; F:identical protein binding; TAS:BHF-UCL; . GO GO:0015631; F:tubulin binding; TAS:BHF-UCL; . GO GO:0007015; P:actin filament organization; TAS:BHF-UCL; . GO GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL; . GO GO:0030388; P:fructose 1; 6-bisphosphate metabolic process; IDA:BHF-UCL GO GO:0006094; P:gluconeogenesis; TAS:Reactome; . GO GO:0006096; P:glycolysis; IMP:BHF-UCL; . GO GO:0046716; P:muscle cell homeostasis; IMP:BHF-UCL; . GO GO:0030168; P:platelet activation; TAS:Reactome; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0051289; P:protein homotetramerization; ISS:UniProtKB; . GO GO:0008360; P:regulation of cell shape; IDA:BHF-UCL; . GO GO:0006941; P:striated muscle contraction; IMP:BHF-UCL; . InterPro IPR000741; Aldolase_I; . InterPro IPR013785; Aldolase_TIM; . Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1; . PANTHER PTHR11627; Aldolase_I; 1; . Pfam PF00274; Glycolytic; 1; . PROSITE PS00158; ALDOLASE_CLASS_I; 1; . SWISS-2DPAGE (search AC)