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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P09651




SWISS-2DPAGE:  P09651


P09651


General information about the entry
View entry in simple text format
Entry nameROA1_HUMAN
Primary accession numberP09651
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP A1; AltName: Full=Helix-destabilizing protein; AltName: Full=Single-strand RNA-binding protein; AltName: Full=hnRNP core protein A1;.
Gene nameName=HNRNPA1
Synonyms=HNRPA1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=35286  [identification data]
Mw=34821  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP09651; ROA1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameROA1_HUMAN
Primary accession numberP09651
Secondary accession number(s) A8K4Z8 Q3MIB7 Q6PJZ7
Sequence was last modified on February 9, 2010 (version 5)
Annotations were last modified on October 19, 2011 (version 165)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP A1; AltName: Full=Helix-destabilizing protein; AltName: Full=Single-strand RNA-binding protein; AltName: Full=hnRNP core protein A1;
Gene nameName=HNRNPA1
Synonyms=HNRPA1
Encoded onName=HNRNPA1; Synonyms=HNRPA1
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Isopeptide bond; Methylation; mRNA processing; mRNA splicing; mRNA transport; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding; Spliceosome; Transport; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX12671; CAA31191.1; -; Genomic_DNA
EMBLX06747; CAA29922.1; -; mRNA
EMBLX79536; CAA56072.1; -; mRNA
EMBLAK291113; BAF83802.1; -; mRNA
EMBLAC078778; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471054; EAW96761.1; -; Genomic_DNA
EMBLBC002355; AAH02355.1; -; mRNA
EMBLBC009600; AAH09600.1; -; mRNA
EMBLBC012158; AAH12158.1; -; mRNA
EMBLBC033714; AAH33714.1; -; mRNA
EMBLBC052296; AAH52296.1; -; mRNA
EMBLBC070315; AAH70315.1; -; mRNA
EMBLBC074502; AAH74502.1; -; mRNA
EMBLBC103707; AAI03708.1; -; mRNA
EMBLX04347; CAA27874.1; -; mRNA
IPIIPI00215965; -; .
IPIIPI00465365; -; .
IPIIPI00797148; -; .
PIRS02061; S02061; .
PIRS12520; S12520; .
RefSeqNP_002127.1; NM_002136.2; .
RefSeqNP_112420.1; NM_031157.2; .
UniGeneHs.546261; -; .
UniGeneHs.655424; -; .
PDB1HA1; X-ray; 1.75 A; A=1-184
PDB1L3K; X-ray; 1.10 A; A=1-196
PDB1PGZ; X-ray; 2.60 A; A=2-195
PDB1PO6; X-ray; 2.10 A; A=8-189
PDB1U1K; X-ray; 2.00 A; A=1-196
PDB1U1L; X-ray; 2.00 A; A=1-196
PDB1U1M; X-ray; 2.00 A; A=1-196
PDB1U1N; X-ray; 2.10 A; A=1-196
PDB1U1O; X-ray; 2.00 A; A=1-196
PDB1U1P; X-ray; 1.90 A; A=1-196
PDB1U1Q; X-ray; 1.80 A; A=1-196
PDB1U1R; X-ray; 1.80 A; A=1-196
PDB1UP1; X-ray; 1.90 A; A=3-184
PDB2H4M; X-ray; 3.05 A; C/D=309-357
PDB2UP1; X-ray; 2.10 A; A=8-190
PDBsum1HA1; -; .
PDBsum1L3K; -; .
PDBsum1PGZ; -; .
PDBsum1PO6; -; .
PDBsum1U1K; -; .
PDBsum1U1L; -; .
PDBsum1U1M; -; .
PDBsum1U1N; -; .
PDBsum1U1O; -; .
PDBsum1U1P; -; .
PDBsum1U1Q; -; .
PDBsum1U1R; -; .
PDBsum1UP1; -; .
PDBsum2H4M; -; .
PDBsum2UP1; -; .
ProteinModelPortalP09651; -; .
SMRP09651; 8-190; .
DisProtDP00324; -; .
DIPDIP-29338N; -; .
IntActP09651; 49; .
MINTMINT-1035550; -; .
STRINGP09651; -; .
PhosphoSiteP09651; -; .
SWISS-2DPAGEP09651; -; .
Aarhus/Ghent-2DPAGE207; NEPHGE; .
Aarhus/Ghent-2DPAGE2114; NEPHGE; .
Aarhus/Ghent-2DPAGE3612; NEPHGE; .
PRIDEP09651; -; .
EnsemblENST00000340913; ENSP00000341826; ENSG00000135486; .
EnsemblENST00000420780; ENSP00000391986; ENSG00000135486; .
GeneID3178; -; .
KEGGhsa:3178; -; .
UCSCuc001sfl.1; human; .
UCSCuc001sfn.1; human; .
UCSCuc009zng.1; human; .
CTD3178; -; .
GeneCardsGC12P051713; -; .
HGNCHGNC:5031; HNRNPA1; .
HPACAB010894; -; .
HPAHPA001666; -; .
MIM164017; gene; .
neXtProtNX_P09651; -; .
PharmGKBPA162391113; -; .
eggNOGprNOG15016; -; .
GeneTreeENSGT00550000074566; -; .
HOGENOMHBG756718; -; .
HOVERGENHBG002295; -; .
InParanoidP09651; -; .
OMAIEVEIMT; -; .
OrthoDBEOG4HQDKF; -; .
Pathway_Interaction_DBar_pathway; Coregulation of Androgen receptor activity; .
ReactomeREACT_1675; mRNA Processing; .
ReactomeREACT_71; Gene Expression; .
NextBio12614; -; .
ArrayExpressP09651; -; .
BgeeP09651; -; .
CleanExHS_HNRNPA1; -; .
GenevestigatorP09651; -; .
GermOnlineENSG00000135486; Homo sapiens; .
GOGO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; .
GOGO:0005737; C:cytoplasm; IDA:HGNC; .
GOGO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0005654; C:nucleoplasm; IDA:HGNC; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0003697; F:single-stranded DNA binding; IDA:HGNC; .
GOGO:0003727; F:single-stranded RNA binding; IC:HGNC; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
GOGO:0051028; P:mRNA transport; IEA:UniProtKB-KW; .
GOGO:0051170; P:nuclear import; IDA:HGNC; .
GOGO:0000398; P:nuclear mRNA splicing; via spliceosome; IC:UniProtKB
GOGO:0006405; P:RNA export from nucleus; IC:HGNC; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
Gene3DG3DSA:3.30.70.330; a_b_plait_nuc_bd; 1; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
PROSITEPS50102; RRM; 2; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server