Attention: World-2DPAGE is no longer maintained.

Sample Preparation and Post-separation Analysis

P0C0L5:

ID   CO4B_HUMAN; STANDARD; 2DG.
AC   P0C0L5; P01028;
DT   01-AUG-1993, integrated into SWISS-2DPAGE (release 0).
DT   01-DEC-2000, 2D annotation version 1.
DT   19-MAY-2011, general annotation version 13.
DE   RecName: Full=Complement C4-B; AltName: Full=Basic complement C4;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing
DE   protein 3; Contains: RecName: Full=Complement C4 beta chain; Contains:
DE   RecName: Full=Complement C4-B alpha chain; Contains: RecName: Full=C4a
DE   anaphylatoxin; Contains: RecName: Full=C4b-B; Contains: RecName:
DE   Full=C4d-B; Contains: RecName: Full=Complement C4 gamma chain; Flags: Precursor;.
GN   Name=C4B; Synonyms=CO4, CPAMD3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Hominidae; Homo.
OX   NCBI_TaxID=9606;
MT   CSF_HUMAN, HEPG2SP_HUMAN, PLASMA_HUMAN.
IM   CSF_HUMAN, HEPG2SP_HUMAN, PLASMA_HUMAN.
RN   [1]
RP   MAPPING ON GEL.
RX   MEDLINE=93092937; PubMed=1459097; [NCBI, Expasy, EBI, Israel, Japan]
RA   Hughes G.J., Frutiger S., Paquet N., Ravier F., Pasquali C., Sanchez
RA   J.-C., James R.W., Tissot J.-D., Bjellqvist B., Hochstrasser D.F.;
RT   ''''''Plasma protein map: an update by microsequencing'';'';'';
RL   Electrophoresis 13(1):707-714(1992).
RN   [2]
RP   MAPPING ON GEL.
RX   MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
RA   Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch
RA   A., Hochstrasser D.F.;
RT   ''''''Inside SWISS-2DPAGE database'';'';'';
RL   Electrophoresis 16(1):1131-1151(1995).
CC   -!- SUBUNIT: ALPHA, BETA AND GAMMA CHAIN 
2D   -!- MASTER: CSF_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000C7Y=6.39/30097;
2D   -!-   PI/MW: SPOT 2D-000C86=6.54/29949;
2D   -!-   MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D   -!- MASTER: HEPG2SP_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0009D6=6.78/27155;
2D   -!-   PI/MW: SPOT 2D-0009D7=6.52/27030;
2D   -!-   MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D   -!- MASTER: PLASMA_HUMAN;
2D   -!-   PI/MW: SPOT 2D-00058V=6.41/31942;
2D   -!-   PI/MW: SPOT 2D-00058Y=6.54/31735;
2D   -!-   NORMAL LEVEL: 200-500 MG/L.
2D   -!-   PATHOLOGICAL LEVEL: DECREASED DURING LUPUS ERYTHEMATOSUS AND
2D         HEREDITARY ANGIOEDEMA.
2D   -!-   POSITIONAL VARIANTS: MORE THAN 10 VARIANTS.
2D   -!-   MAPPING: MICROSEQUENCING [1].
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DR   DOSAC-COBS-2DPAGE; P0C0L5; CO4B_HUMAN.
DR   UniProtKB/Swiss-Prot; P0C0L5; CO4B_HUMAN.
//

The following 2-D maps are available for this protein:

	Cerebrospinal Fluid	HepG2 Secreted Proteins	Plasma

SWISS-2DPAGE (search AC)