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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P13645



General information about the entry
View entry in simple text format
Entry nameK1C10_HUMAN
Primary accession numberP13645
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type I cytoskeletal 10; AltName: Full=Cytokeratin-10; Short=CK-10; AltName: Full=Keratin-10; Short=K10;.
Gene nameName=KRT10
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

pI=6.19; Mw=52478  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP13645; K1C10_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameK1C10_HUMAN
Primary accession numberP13645
Secondary accession number(s) Q14664 Q8N175
Sequence was last modified on November 24, 2009 (version 6)
Annotations were last modified on October 19, 2011 (version 127)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type I cytoskeletal 10; AltName: Full=Cytokeratin-10; Short=CK-10; AltName: Full=Keratin-10; Short=K10;
Gene nameName=KRT10
Encoded onName=KRT10; Synonyms=KPP
Keywords3D-structure; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Ichthyosis; Intermediate filament; Keratin; Phosphoprotein; Polymorphism; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLJ04029; AAA60544.1; -; mRNA
EMBLX14487; CAA32649.1; -; Genomic_DNA
EMBLBC034697; AAH34697.1; -; mRNA
EMBLM19156; AAA59468.1; ALT_INIT; mRNA
EMBLL20218; AAB59438.1; -; Genomic_DNA
EMBLL20219; AAB59439.1; -; Genomic_DNA
EMBLM77663; AAA59199.1; -; mRNA
IPIIPI00009865; -; .
PIRA31994; A31994; .
PIRS02158; KRHU0; .
RefSeqNP_000412.3; NM_000421.3; .
UniGeneHs.99936; -; .
PDB3ASW; X-ray; 2.60 A; B=473-487
PDBsum3ASW; -; .
ProteinModelPortalP13645; -; .
SMRP13645; 144-181; 195-295; 313-455
IntActP13645; 16; .
MINTMINT-1132575; -; .
STRINGP13645; -; .
PhosphoSiteP13645; -; .
SWISS-2DPAGEP13645; -; .
Aarhus/Ghent-2DPAGE7405; IEF; .
PeptideAtlasP13645; -; .
PRIDEP13645; -; .
EnsemblENST00000269576; ENSP00000269576; ENSG00000186395; .
GeneID3858; -; .
KEGGhsa:3858; -; .
UCSCuc002hvi.1; human; .
CTD3858; -; .
GeneCardsGC17M034768; -; .
HGNCHGNC:6413; KRT10; .
HPACAB000132; -; .
HPAHPA012014; -; .
MIM113800; phenotype; .
MIM148080; gene; .
MIM607602; phenotype; .
MIM609165; phenotype; .
neXtProtNX_P13645; -; .
Orphanet312; Congenital bullous ichthyosiform erythroderma; .
Orphanet313; Lamellar ichthyosis; .
PharmGKBPA30200; -; .
eggNOGprNOG05122; -; .
GeneTreeENSGT00560000077101; -; .
HOGENOMHBG715391; -; .
HOVERGENHBG013015; -; .
InParanoidP13645; -; .
OrthoDBEOG4P8FJH; -; .
NextBio15181; -; .
ArrayExpressP13645; -; .
BgeeP13645; -; .
CleanExHS_KRT10; -; .
GenevestigatorP13645; -; .
GermOnlineENSG00000186395; Homo sapiens; .
GOGO:0030280; F:structural constituent of epidermis; NAS:UniProtKB; .
GOGO:0008544; P:epidermis development; TAS:ProtInc; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR018039; Intermediate_filament_CS; .
InterProIPR002957; Keratin_I; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PROSITEPS00226; IF; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server