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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P20700




SWISS-2DPAGE:  P20700


P20700


General information about the entry
View entry in simple text format
Entry nameLMNB1_HUMAN
Primary accession numberP20700
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onDecember 1, 2000 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Lamin-B1; Flags: Precursor;.
Gene nameName=LMNB1
Synonyms=LMN2, LMNB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=20529951; PubMed=11079567; [NCBI, Expasy, EBI, Israel, Japan]
Jung E., Hoogland C., Chiappe D., Sanchez J.-C., Hochstrasser D.F.
''''''The establishment of a human liver nuclei 2-DE reference map'';'';''
Electrophoresis 21(1):3483-3487(2000)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEI_LIVER_HUMAN {Soluble nuclear proteins and matrix from liver tissue}
Homo sapiens (Human)
Tissue: Liver
NUCLEI_LIVER_HUMAN
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_HUMAN

MAP LOCATIONS:
pI=6.10; Mw=26847  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP20700; LMNB1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameLMNB1_HUMAN
Primary accession numberP20700
Secondary accession number(s) B2R6J6 Q3SYN7 Q96EI6
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 124)
Name and origin of the protein
DescriptionRecName: Full=Lamin-B1; Flags: Precursor;
Gene nameName=LMNB1
Synonyms=LMN2, LMNB
Encoded onName=LMNB1; Synonyms=LMN2, LMNB
Keywords3D-structure; Acetylation; Chromosomal rearrangement; Coiled coil; Complete proteome; Direct protein sequencing; Intermediate filament; Leukodystrophy; Lipoprotein; Membrane; Methylation; Nucleus; Phosphoprotein; Polymorphism; Prenylation; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM34458; AAA36162.1; -; mRNA
EMBLL37747; AAC37575.1; -; Genomic_DNA
EMBLL37737; AAC37575.1; JOINED; Genomic_DNA
EMBLL37738; AAC37575.1; JOINED; Genomic_DNA
EMBLL37739; AAC37575.1; JOINED; Genomic_DNA
EMBLL37740; AAC37575.1; JOINED; Genomic_DNA
EMBLL37741; AAC37575.1; JOINED; Genomic_DNA
EMBLL37742; AAC37575.1; JOINED; Genomic_DNA
EMBLL37743; AAC37575.1; JOINED; Genomic_DNA
EMBLL37744; AAC37575.1; JOINED; Genomic_DNA
EMBLL37745; AAC37575.1; JOINED; Genomic_DNA
EMBLL37746; AAC37575.1; JOINED; Genomic_DNA
EMBLAK312603; BAG35493.1; -; mRNA
EMBLCH471086; EAW48846.1; -; Genomic_DNA
EMBLBC012295; AAH12295.1; -; mRNA
EMBLBC103723; AAI03724.1; -; mRNA
IPIIPI00217975; -; .
PIRA34707; VEHULB; .
RefSeqNP_005564.1; NM_005573.3; .
UniGeneHs.89497; -; .
PDB2KPW; NMR; -; A=439-549
PDB3HN9; X-ray; 2.00 A; A/B/C=428-550
PDB3JT0; X-ray; 2.39 A; A/B=426-558
PDB3MOV; X-ray; 2.40 A; A/B=311-388
PDBsum2KPW; -; .
PDBsum3HN9; -; .
PDBsum3JT0; -; .
PDBsum3MOV; -; .
ProteinModelPortalP20700; -; .
SMRP20700; 31-67; 242-309; 311-385
431-548.
IntActP20700; 11; .
MINTMINT-3009331; -; .
STRINGP20700; -; .
PhosphoSiteP20700; -; .
SWISS-2DPAGEP20700; -; .
Aarhus/Ghent-2DPAGE7510; IEF; .
PeptideAtlasP20700; -; .
PRIDEP20700; -; .
EnsemblENST00000261366; ENSP00000261366; ENSG00000113368; .
GeneID4001; -; .
KEGGhsa:4001; -; .
UCSCuc003kud.1; human; .
CTD4001; -; .
GeneCardsGC05P121304; -; .
H-InvDBHIX0005134; -; .
HGNCHGNC:6637; LMNB1; .
HPACAB005269; -; .
MIM150340; gene; .
MIM169500; phenotype; .
neXtProtNX_P20700; -; .
Orphanet99027; Adult-onset autosomal dominant leukodystrophy; .
PharmGKBPA30403; -; .
eggNOGprNOG18280; -; .
HOGENOMHBG716303; -; .
HOVERGENHBG013015; -; .
InParanoidP20700; -; .
OMAHQQGTPR; -; .
OrthoDBEOG45MN55; -; .
PhylomeDBP20700; -; .
Pathway_Interaction_DBcaspase_pathway; Caspase cascade in apoptosis; .
ReactomeREACT_578; Apoptosis; .
ReactomeREACT_75792; Meiotic Synapsis; .
NextBio15700; -; .
PMAP-CutDBP20700; -; .
ArrayExpressP20700; -; .
BgeeP20700; -; .
CleanExHS_LMNB1; -; .
GenevestigatorP20700; -; .
GermOnlineENSG00000113368; Homo sapiens; .
GOGO:0005638; C:lamin filament; TAS:ProtInc; .
GOGO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell; .
GOGO:0005198; F:structural molecule activity; TAS:ProtInc; .
GOGO:0006921; P:cellular component disassembly involved in apoptosis; TAS:Reactome; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR001322; IF_tail_C; .
InterProIPR018039; Intermediate_filament_CS; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PfamPF00932; IF_tail; 1; .
PROSITEPS00226; IF; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server