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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P26447



General information about the entry
View entry in simple text format
Entry nameS10A4_HUMAN
Primary accession numberP26447
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=Protein S100-A4; AltName: Full=Calvasculin; AltName: Full=Metastasin; AltName: Full=Placental calcium-binding protein; AltName: Full=Protein Mts1; AltName: Full=S100 calcium-binding protein A4;.
Gene nameName=S100A4
Synonyms=CAPL, MTS1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

Homo sapiens (Human)
Tissue: Lymphocyte
  map experimental info
  protein estimated location

pI=5.42; Mw=15461  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

pI=5.72; Mw=14400  [identification data]

MAPPING (identification):
Peptide mass fingerprinting and tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
DOSAC-COBS 2D-PAGEP26447; P26447.
UniProtKB/Swiss-ProtP26447; S10A4_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameS10A4_HUMAN
Primary accession numberP26447
Secondary accession number(s) A8K7R8 D3DV46 Q6ICP8
Sequence was last modified on August 1, 1992 (version 1)
Annotations were last modified on September 21, 2011 (version 119)
Name and origin of the protein
DescriptionRecName: Full=Protein S100-A4; AltName: Full=Calvasculin; AltName: Full=Metastasin; AltName: Full=Placental calcium-binding protein; AltName: Full=Protein Mts1; AltName: Full=S100 calcium-binding protein A4;
Gene nameName=S100A4
Synonyms=CAPL, MTS1
Encoded onName=S100A4; Synonyms=CAPL, MTS1
Keywords3D-structure; Acetylation; Calcium; Complete proteome; Direct protein sequencing; Reference proteome; Repeat.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM80563; AAA51920.1; -; mRNA
EMBLZ18950; CAA79474.1; -; Genomic_DNA
EMBLZ33457; CAA83880.1; -; Genomic_DNA
EMBLCR450345; CAG29341.1; -; mRNA
EMBLAK292083; BAF84772.1; -; mRNA
EMBLBX470102; CAI14754.1; -; Genomic_DNA
EMBLCH471121; EAW53310.1; -; Genomic_DNA
EMBLCH471121; EAW53311.1; -; Genomic_DNA
EMBLCH471121; EAW53312.1; -; Genomic_DNA
EMBLCH471121; EAW53313.1; -; Genomic_DNA
EMBLCH471121; EAW53314.1; -; Genomic_DNA
EMBLCH471121; EAW53315.1; -; Genomic_DNA
EMBLBC000838; AAH00838.1; -; mRNA
EMBLBC016300; AAH16300.1; -; mRNA
IPIIPI00032313; -; .
PIRA48219; A48219; .
RefSeqNP_002952.1; NM_002961.2; .
RefSeqNP_062427.1; NM_019554.2; .
UniGeneHs.654444; -; .
PDB1M31; NMR; -; A/B=1-101
PDB2Q91; X-ray; 1.63 A; A/B=1-101
PDB3C1V; X-ray; 1.50 A; A/B/C/D=1-101
PDB3CGA; X-ray; 2.03 A; A/B=1-101
PDB3KO0; X-ray; 2.30 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=1-101
PDB3M0W; X-ray; 2.80 A; A/B/C/D/E/F/G/H/I/J=2-101
PDBsum1M31; -; .
PDBsum2Q91; -; .
PDBsum3C1V; -; .
PDBsum3CGA; -; .
PDBsum3KO0; -; .
PDBsum3M0W; -; .
ProteinModelPortalP26447; -; .
SMRP26447; 2-98; .
IntActP26447; 4; .
MINTMINT-1372269; -; .
STRINGP26447; -; .
PhosphoSiteP26447; -; .
SWISS-2DPAGEP26447; -; .
Cornea-2DPAGEP26447; -; .
PeptideAtlasP26447; -; .
PRIDEP26447; -; .
EnsemblENST00000354332; ENSP00000346294; ENSG00000196154; .
EnsemblENST00000368714; ENSP00000357703; ENSG00000196154; .
EnsemblENST00000368715; ENSP00000357704; ENSG00000196154; .
EnsemblENST00000368716; ENSP00000357705; ENSG00000196154; .
GeneID6275; -; .
KEGGhsa:6275; -; .
UCSCuc001fby.1; human; .
CTD6275; -; .
GeneCardsGC01M124879; -; .
H-InvDBHIX0001081; -; .
HGNCHGNC:10494; S100A4; .
HPACAB002618; -; .
HPACAB027387; -; .
HPAHPA007973; -; .
MIM114210; gene; .
neXtProtNX_P26447; -; .
PharmGKBPA34906; -; .
eggNOGprNOG20778; -; .
GeneTreeENSGT00600000084162; -; .
HOGENOMHBG716817; -; .
HOVERGENHBG001479; -; .
InParanoidP26447; -; .
OrthoDBEOG4NS3D1; -; .
PhylomeDBP26447; -; .
NextBio24355; -; .
ArrayExpressP26447; -; .
BgeeP26447; -; .
CleanExHS_S100A4; -; .
GenevestigatorP26447; -; .
GermOnlineENSG00000196154; Homo sapiens; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; .
GOGO:0005509; F:calcium ion binding; TAS:ProtInc; .
GOGO:0050786; F:RAGE receptor binding; IPI:UniProtKB; .
GOGO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC; .
GOGO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR001751; S100/CaBP-9k_CS; .
InterProIPR013787; S100_Ca-bd_sub; .
Gene3DG3DSA:; EF-Hand_type; 1; .
PfamPF01023; S_100; 1; .
PROSITEPS00018; EF_HAND_1; 1; .
PROSITEPS50222; EF_HAND_2; 1; .
PROSITEPS00303; S100_CABP; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server