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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P29508



General information about the entry
View entry in simple text format
Entry nameSPB3_HUMAN
Primary accession numberP29508
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=Serpin B3; AltName: Full=Protein T4-A; AltName: Full=Squamous cell carcinoma antigen 1; Short=SCCA-1;.
Gene nameName=SERPINB3
Synonyms=SCCA, SCCA1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=73806  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP29508; SPB3_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameSPB3_HUMAN
Primary accession numberP29508
Secondary accession number(s) A6NDM2 B2RBT5 Q53H28 Q53YB5 Q86VF3 Q86W04 Q8IWL4 Q8IXI3 Q96J21 Q9BYF8
Sequence was last modified on January 23, 2002 (version 2)
Annotations were last modified on October 19, 2011 (version 116)
Name and origin of the protein
DescriptionRecName: Full=Serpin B3; AltName: Full=Protein T4-A; AltName: Full=Squamous cell carcinoma antigen 1; Short=SCCA-1;
Gene nameName=SERPINB3
Synonyms=SCCA, SCCA1
Encoded onName=SERPINB3; Synonyms=SCCA, SCCA1
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Polymorphism; Protease inhibitor; Reference proteome; Serine protease inhibitor.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLS66896; AAB20405.1; -; mRNA
EMBLU19556; AAA97552.1; -; mRNA
EMBLU19568; AAA86317.1; -; Genomic_DNA
EMBLU19559; AAA86317.1; JOINED; Genomic_DNA
EMBLU19560; AAA86317.1; JOINED; Genomic_DNA
EMBLU19562; AAA86317.1; JOINED; Genomic_DNA
EMBLU19565; AAA86317.1; JOINED; Genomic_DNA
EMBLU19567; AAA86317.1; JOINED; Genomic_DNA
EMBLU19562; AAA86316.1; -; Genomic_DNA
EMBLU19559; AAA86316.1; JOINED; Genomic_DNA
EMBLU19560; AAA86316.1; JOINED; Genomic_DNA
EMBLAB046399; BAB40772.1; -; mRNA
EMBLAJ515706; CAD56658.1; -; mRNA
EMBLAY245778; AAO92269.1; -; mRNA
EMBLAY245781; AAO92272.1; -; mRNA
EMBLBT006748; AAP35394.1; -; mRNA
EMBLAK222746; BAD96466.1; -; mRNA
EMBLAK222753; BAD96473.1; -; mRNA
EMBLAK314805; BAG37332.1; -; mRNA
EMBLCH471096; EAW63156.1; -; Genomic_DNA
EMBLCH471096; EAW63157.1; -; Genomic_DNA
EMBLBC005224; AAH05224.1; -; mRNA
EMBLAY190327; AAO11731.1; ALT_INIT; mRNA
IPIIPI00022204; -; .
IPIIPI00307466; -; .
PIRI38201; I38201; .
RefSeqNP_008850.1; NM_006919.2; .
UniGeneHs.227948; -; .
PDB2ZV6; X-ray; 2.70 A; A/B/C=2-390
PDBsum2ZV6; -; .
ProteinModelPortalP29508; -; .
SMRP29508; 2-390; .
IntActP29508; 2; .
MINTMINT-1139917; -; .
STRINGP29508; -; .
SWISS-2DPAGEP29508; -; .
UCD-2DPAGEP29508; -; .
PRIDEP29508; -; .
EnsemblENST00000283752; ENSP00000283752; ENSG00000057149; .
GeneID6317; -; .
KEGGhsa:6317; -; .
UCSCuc002lji.1; human; .
UCSCuc010dqa.1; human; .
CTD6317; -; .
GeneCardsGC18M058022; -; .
HPACAB018772; -; .
MIM600517; gene; .
neXtProtNX_P29508; -; .
PharmGKBPA35538; -; .
eggNOGprNOG12352; -; .
HOVERGENHBG005957; -; .
InParanoidP29508; -; .
OrthoDBEOG4FBHTJ; -; .
NextBio24512; -; .
ArrayExpressP29508; -; .
BgeeP29508; -; .
GenevestigatorP29508; -; .
GermOnlineENSG00000206073; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005576; C:extracellular region; IBA:RefGenome; .
GOGO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome; .
GOGO:0030162; P:regulation of proteolysis; IBA:RefGenome; .
InterProIPR000215; Protease_inhib_I4_serpin; .
InterProIPR023795; Protease_inhib_I4_serpin_CS; .
InterProIPR023796; Sepin_dom; .
PANTHERPTHR11461; Prot_inh_serpin; 1; .
PfamPF00079; Serpin; 1; .
SMARTSM00093; SERPIN; 1; .
SUPFAMSSF56574; Prot_inh_serpin; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server