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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P30044




SWISS-2DPAGE:  P30044


P30044


General information about the entry
View entry in simple text format
Entry namePRDX5_HUMAN
Primary accession numberP30044
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 15)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-5, mitochondrial; EC=1.11.1.15; AltName: Full=Alu corepressor 1; AltName: Full=Antioxidant enzyme B166; Short=AOEB166; AltName: Full=Liver tissue 2D-page spot 71B; AltName: Full=PLP; AltName: Full=Peroxiredoxin V; Short=Prx-V; AltName: Full=Peroxisomal antioxidant enzyme; AltName: Full=TPx type VI; AltName: Full=Thioredoxin peroxidase PMP20; AltName: Full=Thioredoxin reductase; Flags: Precursor;.
Gene nameName=PRDX5
Synonyms=ACR1
ORFNames=SBBI10
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=7.07; Mw=14514

MAPPING (identification):
MICROSEQUENCING (XPIKVDDAIP) [1].



U937_HUMAN {Macrophage Like Cell Line}
Homo sapiens (Human)
Tissue: Histiocytic lymphoma
U937_HUMAN
  map experimental info
  protein estimated location
 
U937_HUMAN

MAP LOCATIONS:
pI=6.95; Mw=13972

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP30044.
REPRODUCTION-2DPAGEIPI00759663; IPI00759663.
Siena-2DPAGEP30044; PRDX5_HUMAN.
UCD-2DPAGEP30044; PRDX5_HUMAN.
UniProtKB/Swiss-ProtP30044; PRDX5_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRDX5_HUMAN
Primary accession numberP30044
Secondary accession number(s) Q14CK0 Q6IAF2 Q9UBU5 Q9UJU4 Q9UKX4
Sequence was last modified on January 11, 2011 (version 4)
Annotations were last modified on October 19, 2011 (version 126)
Name and origin of the protein
DescriptionRecName: Full=Peroxiredoxin-5, mitochondrial; EC=1.11.1.15; AltName: Full=Alu corepressor 1; AltName: Full=Antioxidant enzyme B166; Short=AOEB166; AltName: Full=Liver tissue 2D-page spot 71B; AltName: Full=PLP; AltName: Full=Peroxiredoxin V; Short=Prx-V; AltName: Full=Peroxisomal antioxidant enzyme; AltName: Full=TPx type VI; AltName: Full=Thioredoxin peroxidase PMP20; AltName: Full=Thioredoxin reductase; Flags: Precursor;
Gene nameName=PRDX5
Synonyms=ACR1
ORFNames=SBBI10
Encoded onName=PRDX5; Synonyms=ACR1; ORFNames=SBBI10
Keywords3D-structure; Acetylation; Alternative initiation; Antioxidant; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Mitochondrion; Oxidoreductase; Peroxidase; Peroxisome; Polymorphism; Redox-active center; Reference proteome; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF231705; AAF78899.1; -; mRNA
EMBLAF124993; AAF27531.1; -; mRNA
EMBLAF110731; AAF03750.1; -; mRNA
EMBLAF197952; AAF04856.1; -; mRNA
EMBLAJ249483; CAB62210.1; -; mRNA
EMBLAF242525; AAF99605.1; -; mRNA
EMBLAF112212; AAF17200.1; ALT_FRAME; mRNA
EMBLCR457203; CAG33484.1; -; mRNA
EMBLDQ247769; ABB05181.1; -; Genomic_DNA
EMBLAP001453; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAP003774; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC110983; AAI10984.1; -; mRNA
EMBLBC113723; AAI13724.1; -; mRNA
EMBLBC113725; AAI13726.1; -; mRNA
IPIIPI00024915; -; .
IPIIPI00759663; -; .
RefSeqNP_036226.1; NM_012094.4; .
RefSeqNP_857634.1; NM_181651.2; .
RefSeqNP_857635.1; NM_181652.2; .
UniGeneHs.502823; -; .
PDB1H4O; X-ray; 1.95 A; A/B/C/D/E/F/G/H=54-214
PDB1HD2; X-ray; 1.50 A; A=54-214
PDB1OC3; X-ray; 2.00 A; A/B/C=54-214
PDB1URM; X-ray; 1.70 A; A=54-214
PDB2VL2; X-ray; 1.92 A; A/B/C=54-214
PDB2VL3; X-ray; 1.83 A; A/B/C=54-214
PDB2VL9; X-ray; 2.70 A; A/B/C/D=54-214
PDB3MNG; X-ray; 1.45 A; A=54-214
PDBsum1H4O; -; .
PDBsum1HD2; -; .
PDBsum1OC3; -; .
PDBsum1URM; -; .
PDBsum2VL2; -; .
PDBsum2VL3; -; .
PDBsum2VL9; -; .
PDBsum3MNG; -; .
ProteinModelPortalP30044; -; .
SMRP30044; 54-214; .
IntActP30044; 3; .
MINTMINT-5002532; -; .
STRINGP30044; -; .
PeroxiBase4448; HsPrxV; .
PhosphoSiteP30044; -; .
SWISS-2DPAGEP30044; -; .
OGPP30044; -; .
REPRODUCTION-2DPAGEIPI00759663; -; .
UCD-2DPAGEP30044; -; .
PRIDEP30044; -; .
EnsemblENST00000265462; ENSP00000265462; ENSG00000126432; .
GeneID25824; -; .
KEGGhsa:25824; -; .
UCSCuc001nzu.1; human; .
CTD25824; -; .
GeneCardsGC11P060413; -; .
H-InvDBHIX0021287; -; .
HGNCHGNC:9355; PRDX5; .
HPACAB008661; -; .
MIM606583; gene; .
neXtProtNX_P30044; -; .
eggNOGprNOG20098; -; .
GeneTreeENSGT00390000018173; -; .
HOGENOMHBG493509; -; .
HOVERGENHBG053675; -; .
InParanoidP30044; -; .
OMARFSMVIE; -; .
PhylomeDBP30044; -; .
DrugBankDB00995; Auranofin; .
NextBio47091; -; .
ArrayExpressP30044; -; .
BgeeP30044; -; .
CleanExHS_PRDX5; -; .
GenevestigatorP30044; -; .
GermOnlineENSG00000126432; Homo sapiens; .
GOGO:0044445; C:cytosolic part; IDA:UniProtKB; .
GOGO:0005739; C:mitochondrion; IDA:UniProtKB; .
GOGO:0005777; C:peroxisome; IDA:UniProtKB; .
GOGO:0043027; F:caspase inhibitor activity; IMP:UniProtKB; .
GOGO:0004601; F:peroxidase activity; IDA:UniProtKB; .
GOGO:0051920; F:peroxiredoxin activity; IEA:EC; .
GOGO:0034614; P:cellular response to reactive oxygen species; IMP:UniProtKB; .
GOGO:0006954; P:inflammatory response; TAS:UniProtKB; .
GOGO:0043066; P:negative regulation of apoptosis; IMP:UniProtKB; .
InterProIPR013740; Redoxin; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PfamPF08534; Redoxin; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS51352; THIOREDOXIN_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server