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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P30047



General information about the entry
View entry in simple text format
Entry nameGFRP_HUMAN
Primary accession numberP30047
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=GTP cyclohydrolase 1 feedback regulatory protein; Short=GFRP; AltName: Full=GTP cyclohydrolase I feedback regulatory protein; AltName: Full=p35;.
Gene nameName=GCHFR
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
2D PAGE maps for identified proteins
How to interpret a protein

Homo sapiens (Human)
Tissue: Liver
  map experimental info
  protein estimated location

pI=6.61; Mw=10141

MAPPING (identification):

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP30047; GFRP_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameGFRP_HUMAN
Primary accession numberP30047
Secondary accession number(s) B2R4L6 Q2M1Q2 Q99749
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 81)
Name and origin of the protein
DescriptionRecName: Full=GTP cyclohydrolase 1 feedback regulatory protein; Short=GFRP; AltName: Full=GTP cyclohydrolase I feedback regulatory protein; AltName: Full=p35;
Gene nameName=GCHFR
Encoded onName=GCHFR; Synonyms=GFRP
KeywordsComplete proteome; Cytoplasm; Direct protein sequencing; Membrane; Nucleus; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU78190; AAB37337.1; -; Genomic_DNA
EMBLAK311872; BAG34813.1; -; mRNA
EMBLCH471125; EAW92443.1; -; Genomic_DNA
EMBLBC112262; AAI12263.1; -; mRNA
EMBLBC112264; AAI12265.1; -; mRNA
IPIIPI00217253; -; .
RefSeqNP_005249.1; NM_005258.2; .
UniGeneHs.631717; -; .
ProteinModelPortalP30047; -; .
SMRP30047; 2-84; .
IntActP30047; 1; .
STRINGP30047; -; .
PhosphoSiteP30047; -; .
SWISS-2DPAGEP30047; -; .
PeptideAtlasP30047; -; .
PRIDEP30047; -; .
EnsemblENST00000260447; ENSP00000260447; ENSG00000137880; .
GeneID2644; -; .
KEGGhsa:2644; -; .
UCSCuc001zmr.1; human; .
CTD2644; -; .
GeneCardsGC15P017904; -; .
H-InvDBHIX0038162; -; .
MIM602437; gene; .
neXtProtNX_P30047; -; .
PharmGKBPA28609; -; .
eggNOGprNOG21237; -; .
HOGENOMHBG713091; -; .
HOVERGENHBG000233; -; .
InParanoidP30047; -; .
OrthoDBEOG4B5P6V; -; .
PhylomeDBP30047; -; .
NextBio10430; -; .
ArrayExpressP30047; -; .
BgeeP30047; -; .
CleanExHS_GCHFR; -; .
GenevestigatorP30047; -; .
GermOnlineENSG00000137880; Homo sapiens; .
GOGO:0005829; C:cytosol; IEA:UniProtKB-SubCell; .
GOGO:0030425; C:dendrite; IDA:UniProtKB; .
GOGO:0042470; C:melanosome; IDA:UniProtKB; .
GOGO:0031965; C:nuclear membrane; IDA:UniProtKB; .
GOGO:0009890; P:negative regulation of biosynthetic process; IEA:InterPro; .
GOGO:0042133; P:neurotransmitter metabolic process; TAS:ProtInc; .
GOGO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc; .
InterProIPR009112; GTP_CycHdrlase_I_reg; .
Gene3DG3DSA:3.30.1410.10; GTP_cyclohydro_I_reg; 1; .
PfamPF06399; GFRP; 1; .
ProDomPD028559; GTP_CycHdrlase_I_reg; 1; .
SUPFAMSSF69761; GTP_cyclohydro_I_reg; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server