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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P30050



General information about the entry
View entry in simple text format
Entry nameRL12_HUMAN
Primary accession numberP30050
integrated into SWISS-2DPAGE on September 1, 1997 (release 6)
2D Annotations were last modified onMay 15, 2003 (version 3)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L12;.
Gene nameName=RPL12
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
MEDLINE=98163346; PubMed=9504818; [NCBI, ExPASy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.
''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';''
Electrophoresis 18(1):2842-2848(1997)
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=20822  [identification data]
Mw=20347  [identification data]

MAPPING (identification):
Tandem mass spectrometry [2].

CEC_HUMAN {Colorectal epithelia cells}
Homo sapiens (Human)
Tissue: Colon epithelium
  map experimental info
  protein estimated location

pI=5.31; Mw=11038

MAPPING (identification):

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP30050; RL12_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRL12_HUMAN
Primary accession numberP30050
Secondary accession number(s) Q5VVV2 Q6PB27
Sequence was last modified on April 1, 1993 (version 1)
Annotations were last modified on October 19, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L12;
Gene nameName=RPL12
Encoded onName=RPL12
KeywordsAcetylation; Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLL06505; AAA36157.1; -; mRNA
EMBLAL445222; CAH72929.1; -; Genomic_DNA
EMBLCH471090; EAW87669.1; -; Genomic_DNA
EMBLBC050644; AAH50644.1; -; mRNA
EMBLBC059950; AAH59950.1; -; mRNA
EMBLBC094831; AAH94831.1; -; mRNA
EMBLBC105603; AAI05604.1; -; mRNA
IPIIPI00024933; -; .
IPIIPI00816063; -; .
PIRS35531; S35531; .
RefSeqNP_000967.1; NM_000976.3; .
UniGeneHs.408054; -; .
ProteinModelPortalP30050; -; .
SMRP30050; 2-144; .
IntActP30050; 14; .
MINTMINT-2802291; -; .
STRINGP30050; -; .
PhosphoSiteP30050; -; .
SWISS-2DPAGEP30050; -; .
PRIDEP30050; -; .
EnsemblENST00000361436; ENSP00000354739; ENSG00000197958; .
GeneID6136; -; .
KEGGhsa:6136; -; .
UCSCuc004bqy.1; human; .
CTD6136; -; .
GeneCardsGC09M099825; -; .
H-InvDBHIX0008398; -; .
HGNCHGNC:10302; RPL12; .
HPAHPA003403; -; .
MIM180475; gene; .
neXtProtNX_P30050; -; .
PharmGKBPA34665; -; .
eggNOGprNOG06408; -; .
HOVERGENHBG007231; -; .
InParanoidP30050; -; .
OrthoDBEOG473PSB; -; .
PhylomeDBP30050; -; .
ReactomeREACT_13698; Regulation of beta-cell development; .
ReactomeREACT_15380; Diabetes pathways; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_1762; 3' -UTR-mediated translational regulation; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_6167; Influenza Infection; .
ReactomeREACT_71; Gene Expression; .
NextBio23835; -; .
ArrayExpressP30050; -; .
BgeeP30050; -; .
CleanExHS_RPL12; -; .
GenevestigatorP30050; -; .
GermOnlineENSG00000197958; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005840; C:ribosome; IEA:UniProtKB-KW; .
GOGO:0003723; F:RNA binding; IEA:UniProtKB-KW; .
GOGO:0003735; F:structural constituent of ribosome; IEA:InterPro; .
GOGO:0031018; P:endocrine pancreas development; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0006414; P:translational elongation; TAS:Reactome; .
GOGO:0006415; P:translational termination; TAS:Reactome; .
GOGO:0019083; P:viral transcription; TAS:Reactome; .
InterProIPR000911; Ribosomal_L11; .
InterProIPR020783; Ribosomal_L11_C; .
InterProIPR020785; Ribosomal_L11_CS; .
InterProIPR020784; Ribosomal_L11_N; .
Gene3DG3DSA:; Ribosomal_L11; 1; .
Gene3DG3DSA:3.30.1550.10; Ribosomal_L11_N; 1; .
PANTHERPTHR11661; Ribosomal_L11; 1; .
PfamPF00298; Ribosomal_L11; 1; .
PfamPF03946; Ribosomal_L11_N; 1; .
SMARTSM00649; RL11; 1; .
SUPFAMSSF46906; Ribosomal_L11; 1; .
SUPFAMSSF54747; Ribosomal_L11; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server