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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P31930




SWISS-2DPAGE:  P31930


P31930


General information about the entry
View entry in simple text format
Entry nameQCR1_HUMAN
Primary accession numberP31930
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 15)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome b-c1 complex subunit 1, mitochondrial; AltName: Full=Complex III subunit 1; AltName: Full=Core protein I; AltName: Full=Ubiquinol-cytochrome-c reductase complex core protein 1; Flags: Precursor;.
Gene nameName=UQCRC1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
[3]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=5.40; Mw=46098

MAPPING (identification):
MATCHING WITH THE HEPG2 MASTER GEL [3].



HEPG2_HUMAN {HepG2}
Homo sapiens (Human)
Tissue: Hepatoblastoma
HEPG2_HUMAN
  map experimental info
  protein estimated location
 
HEPG2_HUMAN

MAP LOCATIONS:
pI=5.43; Mw=45731

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=5.41; Mw=46211

MAPPING (identification):
MICROSEQUENCING [1].



LYMPHOMA_HUMAN {Lymphoma}
Homo sapiens (Human)
Tissue: Lymphoma
LYMPHOMA_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOMA_HUMAN

MAP LOCATIONS:
pI=5.45; Mw=45667

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
HSC-2DPAGEP31930; HUMAN.
OGP-WWWP31930.
PHCI-2DPAGEP31930; UCR1_HUMAN.
REPRODUCTION-2DPAGEIPI00013847; IPI00013847.
Siena-2DPAGEP31930; UCR1_HUMAN.
UCD-2DPAGEP31930; QCR1_HUMAN.
UniProtKB/Swiss-ProtP31930; QCR1_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameQCR1_HUMAN
Primary accession numberP31930
Secondary accession number(s) B2R7R8 Q96DD2
Sequence was last modified on April 4, 2006 (version 3)
Annotations were last modified on October 19, 2011 (version 121)
Name and origin of the protein
DescriptionRecName: Full=Cytochrome b-c1 complex subunit 1, mitochondrial; AltName: Full=Complex III subunit 1; AltName: Full=Core protein I; AltName: Full=Ubiquinol-cytochrome-c reductase complex core protein 1; Flags: Precursor;
Gene nameName=UQCRC1
Encoded onName=UQCRC1
KeywordsAcetylation; Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Polymorphism; Reference proteome; Respiratory chain; Transit peptide; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLL16842; AAA20046.1; -; mRNA
EMBLD26485; BAA05495.1; -; mRNA
EMBLAK313090; BAG35915.1; -; mRNA
EMBLCH471055; EAW64898.1; -; Genomic_DNA
EMBLBC009586; AAH09586.1; -; mRNA
IPIIPI00013847; -; .
PIRA48043; A48043; .
RefSeqNP_003356.2; NM_003365.2; .
UniGeneHs.119251; -; .
ProteinModelPortalP31930; -; .
SMRP31930; 35-476; .
IntActP31930; 5; .
MINTMINT-3012677; -; .
STRINGP31930; -; .
MEROPSM16.973; -; .
MEROPSM16.981; -; .
PhosphoSiteP31930; -; .
SWISS-2DPAGEP31930; -; .
OGPP31930; -; .
PHCI-2DPAGEP31930; -; .
REPRODUCTION-2DPAGEIPI00013847; -; .
Siena-2DPAGEP31930; -; .
UCD-2DPAGEP31930; -; .
PeptideAtlasP31930; -; .
PRIDEP31930; -; .
EnsemblENST00000203407; ENSP00000203407; ENSG00000010256; .
GeneID7384; -; .
KEGGhsa:7384; -; .
NMPDRfig|9606.3.peg.22483; -; .
UCSCuc003cub.1; human; .
CTD7384; -; .
GeneCardsGC03M048636; -; .
H-InvDBHIX0003290; -; .
HGNCHGNC:12585; UQCRC1; .
HPAHPA002815; -; .
HPAHPA003525; -; .
MIM191328; gene; .
neXtProtNX_P31930; -; .
PharmGKBPA37216; -; .
eggNOGprNOG13385; -; .
GeneTreeENSGT00550000074701; -; .
HOGENOMHBG476859; -; .
HOVERGENHBG006393; -; .
InParanoidP31930; -; .
OMAVANKLCQ; -; .
OrthoDBEOG44BB26; -; .
PhylomeDBP31930; -; .
ReactomeREACT_6305; Respiratory electron transport; ATP synthesis by chemiosmotic coupling; and heat production by uncoupling proteins
DrugBankDB01117; Atovaquone; .
NextBio28912; -; .
ArrayExpressP31930; -; .
BgeeP31930; -; .
CleanExHS_UQCRC1; -; .
GenevestigatorP31930; -; .
GermOnlineENSG00000010256; Homo sapiens; .
GOGO:0004222; F:metalloendopeptidase activity; IEA:InterPro; .
GOGO:0008121; F:ubiquinol-cytochrome-c reductase activity; TAS:ProtInc; .
GOGO:0008270; F:zinc ion binding; IEA:InterPro; .
GOGO:0009060; P:aerobic respiration; TAS:ProtInc; .
GOGO:0006119; P:oxidative phosphorylation; TAS:ProtInc; .
GOGO:0006508; P:proteolysis; IEA:InterPro; .
GOGO:0022904; P:respiratory electron transport chain; TAS:Reactome; .
InterProIPR011249; Metalloenz_metal-bd; .
InterProIPR011237; Pept_M16_core; .
InterProIPR011765; Pept_M16_N; .
InterProIPR007863; Peptidase_M16_C; .
Gene3DG3DSA:3.30.830.10; Pept_M16_core; 2; .
PfamPF00675; Peptidase_M16; 1; .
PfamPF05193; Peptidase_M16_C; 1; .
SUPFAMSSF63411; Metalloenz_metal-bd; 2; .
PROSITEPS00143; INSULINASE; FALSE_NEG; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server