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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P52566



General information about the entry
View entry in simple text format
Entry nameGDIR2_HUMAN
Primary accession numberP52566
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Rho GDP-dissociation inhibitor 2; Short=Rho GDI 2; AltName: Full=Ly-GDI; AltName: Full=Rho-GDI beta;.
Gene nameName=ARHGDIB
Synonyms=GDIA2, GDID4, RAP1GN1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

Homo sapiens (Human)
Tissue: Lymphocyte
  map experimental info
  protein estimated location

pI=5.03; Mw=23952  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP52566; GDIR2_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameGDIR2_HUMAN
Primary accession numberP52566
Secondary accession number(s) B5BU79
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 111)
Name and origin of the protein
DescriptionRecName: Full=Rho GDP-dissociation inhibitor 2; Short=Rho GDI 2; AltName: Full=Ly-GDI; AltName: Full=Rho-GDI beta;
Gene nameName=ARHGDIB
Synonyms=GDIA2, GDID4, RAP1GN1
Encoded onName=ARHGDIB; Synonyms=GDIA2, GDID4, RAP1GN1
Keywords3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; GTPase activation; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLL20688; AAA59539.1; -; mRNA
EMBLX69549; CAA49280.1; -; mRNA
EMBLAF498927; AAM21075.1; -; mRNA
EMBLAB451315; BAG70129.1; -; mRNA
EMBLAB451445; BAG70259.1; -; mRNA
EMBLCH471094; EAW96336.1; -; Genomic_DNA
EMBLBC009200; AAH09200.1; -; mRNA
IPIIPI00003817; -; .
PIRA47742; A47742; .
RefSeqNP_001166.3; NM_001175.4; .
UniGeneHs.504877; -; .
PDB1DS6; X-ray; 2.35 A; B=23-199
PDBsum1DS6; -; .
ProteinModelPortalP52566; -; .
SMRP52566; 23-199; .
DIPDIP-40959N; -; .
IntActP52566; 4; .
MINTMINT-1616342; -; .
STRINGP52566; -; .
PhosphoSiteP52566; -; .
SWISS-2DPAGEP52566; -; .
Aarhus/Ghent-2DPAGE1120; IEF; .
Aarhus/Ghent-2DPAGE8120; IEF; .
OGPP52566; -; .
PRIDEP52566; -; .
EnsemblENST00000228945; ENSP00000228945; ENSG00000111348; .
GeneID397; -; .
KEGGhsa:397; -; .
UCSCuc001rcq.1; human; .
CTD397; -; .
GeneCardsGC12M014864; -; .
H-InvDBHIX0010462; -; .
HPACAB018584; -; .
MIM602843; gene; .
neXtProtNX_P52566; -; .
PharmGKBPA24964; -; .
GeneTreeENSGT00390000006233; -; .
HOGENOMHBG329264; -; .
HOVERGENHBG000206; -; .
InParanoidP52566; -; .
OrthoDBEOG4Q58QJ; -; .
PhylomeDBP52566; -; .
Pathway_Interaction_DBcaspase_pathway; Caspase cascade in apoptosis; .
Pathway_Interaction_DBfaspathway; FAS signaling pathway (CD95); .
ReactomeREACT_11044; Signaling by Rho GTPases; .
NextBio1665; -; .
PMAP-CutDBP52566; -; .
ArrayExpressP52566; -; .
BgeeP52566; -; .
CleanExHS_ARHGDIB; -; .
GenevestigatorP52566; -; .
GermOnlineENSG00000111348; Homo sapiens; .
GOGO:0016023; C:cytoplasmic membrane-bounded vesicle; TAS:ProtInc; .
GOGO:0005856; C:cytoskeleton; TAS:UniProtKB; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW; .
GOGO:0005094; F:Rho GDP-dissociation inhibitor activity; TAS:ProtInc; .
GOGO:0030036; P:actin cytoskeleton organization; TAS:ProtInc; .
GOGO:0006928; P:cellular component movement; TAS:UniProtKB; .
GOGO:0006955; P:immune response; TAS:ProtInc; .
GOGO:0007275; P:multicellular organismal development; TAS:ProtInc; .
GOGO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc; .
GOGO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome; .
GOGO:0007266; P:Rho protein signal transduction; TAS:ProtInc; .
InterProIPR014756; Ig_E-set; .
InterProIPR000406; Rho_GDI; .
Gene3DG3DSA:; Rho_GDI; 1; .
PANTHERPTHR10980; Rho_GDI; 1; .
PfamPF02115; Rho_GDI; 1; .
SUPFAMSSF81296; Ig_E-set; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server