World-2DPAGE Home
Home  |  Contact

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P63038




SWISS-2DPAGE:  P63038


P63038


General information about the entry
View entry in simple text format
Entry nameCH60_MOUSE
Primary accession numberP63038
Secondary accession number(s) P19226
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 2)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor;.
Gene nameName=Hspd1
Synonyms=Hsp60
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
MEDLINE=93162044; PubMed=1286668; [NCBI, ExPASy, EBI, Israel, Japan]
Giometti C.S., Taylor J., Tollaksen S.L.
''''''Mouse liver protein database: a catalog of proteins detected by two- dimensional gel electrophoresis'';'';''
Electrophoresis 13(1):970-991(1992)
[3]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=5.28; Mw=56387
pI=5.27; Mw=56035
pI=5.30; Mw=55859
pI=5.36; Mw=55685
pI=5.33; Mw=55685

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [3].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.26; Mw=58289
pI=5.32; Mw=58000  [identification data]
pI=5.29; Mw=58144  [identification data]

MAPPING (identification):
MATCHING WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1], AND WITH GIOMETTI MOUSE LIVER 2-DE MAP [2], AND MICROSEQUENCING [3]; SPOTS 2D-00139S, 2D-0013A6: Peptide mass fingerprinting [3].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=5.28; Mw=59263
pI=5.31; Mw=59121  [identification data]

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [3];
SPOT 2D-0016QJ: Peptide mass fingerprinting [3].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=5.26; Mw=59338
pI=5.28; Mw=59225
pI=5.31; Mw=59225

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [3].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
COMPLUYEAST-2DPAGEP63038; CH60_MOUSE.
HSC-2DPAGEP19227; RAT.
REPRODUCTION-2DPAGEIPI00308885; IPI00308885.
REPRODUCTION-2DPAGEP63038; P63038.
UCD-2DPAGEP63038; CH60_MOUSE.
UniProtKB/Swiss-ProtP63038; CH60_MOUSE.
World-2DPAGE RepositoryP63038; CH60_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCH60_MOUSE
Primary accession numberP63038
Secondary accession number(s) P19226 P19227 P97602 Q3KQP2 Q3UIP0 Q8C2C7 Q8VEF4
Sequence was last modified on August 31, 2004 (version 1)
Annotations were last modified on September 21, 2011 (version 82)
Name and origin of the protein
DescriptionRecName: Full=60 kDa heat shock protein, mitochondrial; AltName: Full=60 kDa chaperonin; AltName: Full=Chaperonin 60; Short=CPN60; AltName: Full=HSP-65; AltName: Full=Heat shock protein 60; Short=HSP-60; Short=Hsp60; AltName: Full=Mitochondrial matrix protein P1; Flags: Precursor;
Gene nameName=Hspd1
Synonyms=Hsp60
Encoded onName=Hspd1; Synonyms=Hsp60
KeywordsAcetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Direct protein sequencing; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX55023; CAA38762.1; -; mRNA
EMBLAK088844; BAC40607.1; -; mRNA
EMBLAK143882; BAE25581.1; -; mRNA
EMBLAK146831; BAE27466.1; -; mRNA
EMBLBC016400; AAH16400.1; -; mRNA
EMBLBC018545; AAH18545.1; -; mRNA
EMBLBC106112; AAI06113.1; ALT_SEQ; mRNA
EMBLX53584; CAA37653.1; -; mRNA
IPIIPI00308885; -; .
IPIIPI00845678; -; .
PIRS13084; HHMS60; .
RefSeqNP_034607.3; NM_010477.4; .
UniGeneMm.1777; -; .
ProteinModelPortalP63038; -; .
SMRP63038; 27-554; .
IntActP63038; 5; .
MINTMINT-1860238; -; .
STRINGP63038; -; .
SWISS-2DPAGEP63038; -; .
REPRODUCTION-2DPAGEIPI00308885; -; .
REPRODUCTION-2DPAGEP63038; -; .
UCD-2DPAGEP19227; -; .
UCD-2DPAGEP63038; -; .
PRIDEP63038; -; .
EnsemblENSMUST00000027123; ENSMUSP00000027123; ENSMUSG00000025980; .
GeneID15510; -; .
KEGGmmu:15510; -; .
UCSCuc007bab.2; mouse; .
CTD3329; -; .
MGIMGI:96242; Hspd1; .
eggNOGroNOG14286; -; .
GeneTreeENSGT00390000005727; -; .
HOVERGENHBG001982; -; .
InParanoidP63038; -; .
OMAVQSIIPA; -; .
OrthoDBEOG4PK27J; -; .
PhylomeDBP63038; -; .
NextBio288418; -; .
PMAP-CutDBP63038; -; .
BgeeP63038; -; .
CleanExMM_HSPD1; -; .
GenevestigatorP63038; -; .
GermOnlineENSMUSG00000025980; Mus musculus; .
GOGO:0005743; C:mitochondrial inner membrane; IDA:MGI; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0044459; C:plasma membrane part; IDA:MGI; .
GOGO:0030141; C:stored secretory granule; IDA:MGI; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0001530; F:lipopolysaccharide binding; IDA:BHF-UCL; .
GOGO:0032727; P:positive regulation of interferon-alpha production; IDA:MGI; .
GOGO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL; .
GOGO:0050870; P:positive regulation of T cell activation; IDA:BHF-UCL; .
GOGO:0042110; P:T cell activation; IDA:MGI; .
InterProIPR018370; Chaperonin_Cpn60_CS; .
InterProIPR001844; Chaprnin_Cpn60; .
InterProIPR002423; Cpn60/TCP-1; .
PANTHERPTHR11353; Cpn60/TCP-1; 1; .
PfamPF00118; Cpn60_TCP1; 1; .
PRINTSPR00298; CHAPERONIN60; .
SUPFAMSSF48592; GroEL-ATPase; 1; .
TIGRFAMsTIGR02348; GroEL; 1; .
PROSITEPS00296; CHAPERONINS_CPN60; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server