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SWISS-2DPAGE

Attention: World-2DPAGE is no longer maintained.
It will be discontinued on 31-May-2024.

Swiss-2DPAGE data (text records and image files) will continue to be available from https://ftp.expasy.org/databases/swiss-2dpage/.


SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P68369




SWISS-2DPAGE:  P68369


P68369


General information about the entry
View entry in simple text format
Entry nameTBA1A_MOUSE
Primary accession numberP68369
Secondary accession number(s) P02551
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 13)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;.
Gene nameName=Tuba1a
Synonyms=Tuba1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, Expasy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
MEDLINE=93162044; PubMed=1286668; [NCBI, Expasy, EBI, Israel, Japan]
Giometti C.S., Taylor J., Tollaksen S.L.
''''''Mouse liver protein database: a catalog of proteins detected by two- dimensional gel electrophoresis'';'';''
Electrophoresis 13(1):970-991(1992)
[3]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.11; Mw=53504  [identification data]

MAPPING (identification):
MATCHING [3] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1], AND WITH GIOMETTI MOUSE LIVER 2-DE MAP [2], AND MASS FINGERPRINTING [3].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=5.11; Mw=56111

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [3].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=5.08; Mw=53967

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [3].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP68369; TBA1A_MOUSE.
World-2DPAGE RepositoryP68369; TBA1A_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTBA1A_MOUSE
Primary accession numberP68369
Secondary accession number(s) P02551 P05210 P05212 Q3TGF0 Q3TIW2 Q3TPJ1 Q3ULN1 Q5XJF8
Sequence was last modified on July 21, 1986 (version 1)
Annotations were last modified on September 21, 2011 (version 82)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain;
Gene nameName=Tuba1a
Synonyms=Tuba1
Encoded onName=Tuba1a; Synonyms=Tuba1
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM13445; AAA40499.1; -; mRNA
EMBLAK077529; BAC36848.1; -; mRNA
EMBLAK145404; BAE26417.1; -; mRNA
EMBLAK146983; BAE27586.1; -; mRNA
EMBLAK164335; BAE37745.1; -; mRNA
EMBLAK167687; BAE39734.1; -; mRNA
EMBLAK168762; BAE40598.1; -; mRNA
EMBLAK169610; BAE41258.1; -; mRNA
EMBLBC056169; AAH56169.1; -; mRNA
EMBLBC083343; AAH83343.1; -; mRNA
EMBLBC083345; AAH83345.1; -; mRNA
EMBLBC085256; AAH85256.1; -; mRNA
EMBLM28729; AAA40506.1; -; mRNA
EMBLBC083344; AAH83344.1; -; mRNA
IPIIPI00110753; -; .
PIRI77424; I77424; .
RefSeqNP_035783.1; NM_011653.2; .
UniGeneMm.439690; -; .
ProteinModelPortalP68369; -; .
SMRP68369; 1-440; .
IntActP68369; 6; .
MINTMINT-3288915; -; .
STRINGP68369; -; .
PhosphoSiteP68369; -; .
SWISS-2DPAGEP68369; -; .
PRIDEP68369; -; .
EnsemblENSMUST00000097014; ENSMUSP00000094778; ENSMUSG00000072235; .
GeneID22142; -; .
KEGGmmu:22142; -; .
CTD7846; -; .
MGIMGI:98869; Tuba1a; .
GeneTreeENSGT00600000084100; -; .
HOVERGENHBG000089; -; .
InParanoidP68369; -; .
OMAANHEANS; -; .
OrthoDBEOG44J2HZ; -; .
PhylomeDBP68369; -; .
NextBio302038; -; .
PMAP-CutDBP68369; -; .
ArrayExpressP68369; -; .
BgeeP68369; -; .
CleanExMM_TUBA1A; -; .
GenevestigatorP68369; -; .
GermOnlineENSMUSG00000072235; Mus musculus; .
GOGO:0005881; C:cytoplasmic microtubule; IDA:MGI; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR002452; Alpha_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:1.10.287.600; Tubulin_C; 1; .
Gene3DG3DSA:3.40.50.1440; Tubulin_FtsZ; 1; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
PRINTSPR01162; ALPHATUBULIN; .
PRINTSPR01161; TUBULIN; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .
PROSITEPS00227; TUBULIN; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server