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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P99058



General information about the entry
View entry in simple text format
Entry nameSRSF7_HUMAN
Primary accession numberP99058
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Serine/arginine-rich splicing factor 7; AltName: Full=Splicing factor 9G8; AltName: Full=Splicing factor, arginine/serine-rich 7;.
Gene nameName=SRSF7
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=22406  [identification data]
Mw=22074  [identification data]

MAPPING (identification):
BAND 1D-001VA0: Peptide mass fingerprinting [1];
BAND 1D-001VA1: Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtQ16629; SRSF7_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameSRSF7_HUMAN
Primary accession numberQ16629
Secondary accession number(s) Q564D3
Sequence was last modified on November 1, 1996 (version 1)
Annotations were last modified on October 19, 2011 (version 134)
Name and origin of the protein
DescriptionRecName: Full=Serine/arginine-rich splicing factor 7; AltName: Full=Splicing factor 9G8; AltName: Full=Splicing factor, arginine/serine-rich 7;
Gene nameName=SRSF7
Encoded onName=SRSF7; Synonyms=SFRS7
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Metal-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding; Zinc; Zinc-finger.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLL22253; AAA35495.1; -; mRNA
EMBLL41887; AAA88098.1; -; Genomic_DNA
EMBLAB445102; BAI99737.1; -; mRNA
EMBLAY166860; AAN87842.1; -; mRNA
EMBLBT006745; AAP35391.1; -; mRNA
EMBLAY513287; AAT08040.1; -; mRNA
EMBLAC074366; AAX93102.1; -; Genomic_DNA
EMBLCH471053; EAX00366.1; -; Genomic_DNA
EMBLBC000997; AAH00997.1; -; mRNA
EMBLBC017369; AAH17369.1; -; mRNA
EMBLBC017908; AAH17908.1; -; mRNA
EMBLBC022328; AAH22328.1; -; mRNA
IPIIPI00003377; -; .
IPIIPI00744364; -; .
IPIIPI00917346; -; .
PIRA57198; A57198; .
RefSeqNP_001026854.1; NM_001031684.2; .
RefSeqNP_001182375.1; NM_001195446.1; .
UniGeneHs.309090; -; .
PDB2HVZ; NMR; -; A=12-98
PDBsum2HVZ; -; .
ProteinModelPortalQ16629; -; .
SMRQ16629; 12-98; .
IntActQ16629; 9; .
MINTMINT-3032898; -; .
STRINGQ16629; -; .
PhosphoSiteQ16629; -; .
SWISS-2DPAGEP99058; -; .
PRIDEQ16629; -; .
EnsemblENST00000313117; ENSP00000325905; ENSG00000115875; .
GeneID6432; -; .
KEGGhsa:6432; -; .
UCSCuc002rqz.1; human; .
CTD6432; -; .
GeneCardsGC02M038709; -; .
H-InvDBHIX0001988; -; .
HGNCHGNC:10789; SRSF7; .
MIM600572; gene; .
neXtProtNX_Q16629; -; .
PharmGKBPA165697498; -; .
PharmGKBPA35705; -; .
eggNOGprNOG20589; -; .
HOGENOMHBG756718; -; .
HOVERGENHBG107480; -; .
InParanoidQ16629; -; .
OrthoDBEOG4Z62PZ; -; .
PhylomeDBQ16629; -; .
ReactomeREACT_1675; mRNA Processing; .
ReactomeREACT_1788; Transcription; .
ReactomeREACT_71; Gene Expression; .
ReactomeREACT_78; Post-Elongation Processing of the Transcript; .
NextBio24983; -; .
ArrayExpressQ16629; -; .
BgeeQ16629; -; .
CleanExHS_SFRS7; -; .
GenevestigatorQ16629; -; .
GermOnlineENSG00000115875; Homo sapiens; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0003723; F:RNA binding; IEA:UniProtKB-KW; .
GOGO:0008270; F:zinc ion binding; IEA:InterPro; .
GOGO:0031124; P:mRNA 3'-end processing; TAS:Reactome; .
GOGO:0006406; P:mRNA export from nucleus; TAS:Reactome; .
GOGO:0048025; P:negative regulation of nuclear mRNA splicing; via spliceosome; IDA:UniProtKB
GOGO:0000398; P:nuclear mRNA splicing; via spliceosome; TAS:Reactome
GOGO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
InterProIPR013084; Znf_CCH_retrovir; .
InterProIPR001878; Znf_CCHC; .
Gene3DG3DSA:; a_b_plait_nuc_bd; 1; .
Gene3DG3DSA:; Znf_CCH_retrovir; 1; .
PfamPF00076; RRM_1; 1; .
SMARTSM00360; RRM; 1; .
SMARTSM00343; ZnF_C2HC; 1; .
PROSITEPS50102; RRM; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server