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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: PPIB_HUMAN SWISS-2DPAGE:  PPIB_HUMAN PPIB_HUMAN General information about the entry View entry in simple text format Entry name PPIB_HUMAN Primary accession number P23284 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on March 31, 2004 (version 1) General Annotations were last modified on  May 19, 2011 (version 6) Name and origin of the protein Description RecName: Full=Peptidyl-prolyl cis-trans isomerase B; Short=PPIase B; EC=5.2.1.8; AltName: Full=CYP-S1; AltName: Full=Cyclophilin B; AltName: Full=Rotamase B; AltName: Full=S-cyclophilin; Short=SCYLP; Flags: Precursor;. Gene name Name=PPIB Synonyms=CYPB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001VA6: Mw=20347   [identification data] MAPPING (identification): Tandem mass spectrometry and peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references OGP-WWW P23284. REPRODUCTION-2DPAGE IPI00646304; IPI00646304. UniProtKB/Swiss-Prot P23284; PPIB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name PPIB_HUMAN Primary accession number P23284 Secondary accession number(s) A8K534 Q6IBH5 Q9BVK5 Sequence was last modified on  November 25, 2008 (version 2) Annotations were last modified on  October 19, 2011 (version 123) Name and origin of the protein Description RecName: Full=Peptidyl-prolyl cis-trans isomerase B; Short=PPIase B; EC=5.2.1.8; AltName: Full=CYP-S1; AltName: Full=Cyclophilin B; AltName: Full=Rotamase B; AltName: Full=S-cyclophilin; Short=SCYLP; Flags: Precursor; Gene name Name=PPIB Synonyms=CYPB Encoded on Name=PPIB; Synonyms=CYPB Keywords 3D-structure; Complete proteome; Cyclosporin; Direct protein sequencing; Disease mutation; Dwarfism; Endoplasmic reticulum; Glycoprotein; Isomerase; Osteogenesis imperfecta; Polymorphism; Reference proteome; Rotamase; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M63573; AAA36601.1; -; mRNA EMBL AK291149; BAF83838.1; -; mRNA EMBL CR456829; CAG33110.1; -; mRNA EMBL AY962310; AAX44050.1; -; Genomic_DNA EMBL AC100840; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471082; EAW77669.1; -; Genomic_DNA EMBL BC001125; AAH01125.1; -; mRNA EMBL BC008848; AAH08848.1; -; mRNA EMBL BC020800; AAH20800.1; -; mRNA EMBL BC032138; AAH32138.1; -; mRNA EMBL M60857; AAA52150.1; ALT_INIT; mRNA EMBL M60457; AAA35733.1; -; mRNA IPI IPI00646304; -; . PIR A39118; CSHUB; . RefSeq NP_000933.1; NM_000942.4; . UniGene Hs.434937; -; . PDB 1CYN; X-ray; 1.85 A; A=39-216 PDB 3ICH; X-ray; 1.20 A; A=34-216 PDB 3ICI; X-ray; 1.70 A; A/B=34-216 PDBsum 1CYN; -; . PDBsum 3ICH; -; . PDBsum 3ICI; -; . ProteinModelPortal P23284; -; . SMR P23284; 32-216; . IntAct P23284; 10; . MINT MINT-1142578; -; . STRING P23284; -; . PhosphoSite P23284; -; . SWISS-2DPAGE P23284; -; . Aarhus/Ghent-2DPAGE 117; NEPHGE; . OGP P23284; -; . REPRODUCTION-2DPAGE IPI00646304; -; . PRIDE P23284; -; . Ensembl ENST00000300026; ENSP00000300026; ENSG00000166794; . GeneID 5479; -; . KEGG hsa:5479; -; . UCSC uc002and.1; human; . CTD 5479; -; . GeneCards GC15M041272; -; . H-InvDB HIX0012337; -; . HGNC HGNC:9255; PPIB; . HPA CAB011487; -; . HPA HPA012720; -; . MIM 123841; gene; . MIM 259440; phenotype; . neXtProt NX_P23284; -; . Orphanet 216804; Osteogenesis imperfecta type 2; . Orphanet 216812; Osteogenesis imperfecta type 3; . Orphanet 216820; Osteogenesis imperfecta type 4; . PharmGKB PA33580; -; . eggNOG prNOG11714; -; . GeneTree ENSGT00550000074120; -; . HOGENOM HBG610621; -; . HOVERGEN HBG001065; -; . InParanoid P23284; -; . OMA KGPKVTA; -; . OrthoDB EOG43XV4N; -; . PhylomeDB P23284; -; . Pathway_Interaction_DB syndecan_1_pathway; Syndecan-1-mediated signaling events; . DrugBank DB00172; L-Proline; . NextBio 21210; -; . ArrayExpress P23284; -; . Bgee P23284; -; . CleanEx HS_PPIB; -; . Genevestigator P23284; -; . GermOnline ENSG00000166794; Homo sapiens; . GO GO:0005788; C:endoplasmic reticulum lumen; NAS:UniProtKB; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0042277; F:peptide binding; IEA:UniProtKB-KW; . GO GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; NAS:UniProtKB; . GO GO:0051082; F:unfolded protein binding; TAS:ProtInc; . GO GO:0006457; P:protein folding; IEA:UniProtKB-KW; . InterPro IPR015891; Cyclophilin-like; . InterPro IPR020892; Pep-Pro_Isoase_cyclophilin_CS; . InterPro IPR002130; PPIase_cyclophilin; . Gene3D G3DSA:2.40.100.10; PPIase_cyclophilin; 1; . Pfam PF00160; Pro_isomerase; 1; . PRINTS PR00153; CSAPPISMRASE; . SUPFAM SSF50891; CSA_PPIase; 1; . PROSITE PS00170; CSA_PPIASE_1; 1; . PROSITE PS50072; CSA_PPIASE_2; 1; . SWISS-2DPAGE (search AC)