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SWISS-2DPAGE

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It will be discontinued on 31-May-2024.

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: PRPS3_HUMAN




SWISS-2DPAGE:  PRPS3_HUMAN


PRPS3_HUMAN


General information about the entry
View entry in simple text format
Entry namePRPS3_HUMAN
Primary accession numberP21108
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Ribose-phosphate pyrophosphokinase 3; EC=2.7.6.1; AltName: Full=Phosphoribosyl pyrophosphate synthase 1-like 1; Short=PRPS1-like 1; AltName: Full=Phosphoribosyl pyrophosphate synthase III; Short=PRS-III;.
Gene nameName=PRPS1L1
Synonyms=PRPS3, PRPSL
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=94147970; PubMed=8313871; [NCBI, Expasy, EBI, Israel, Japan]
Golaz O., Hughes G.J., Frutiger S., Paquet N., Bairoch A., Pasquali C., Sanchez J.-C., Tissot J.-D., Appel R.D., Walzer C., Balant L.P., Hochstrasser D.F.
''''''Plasma and red blood cell protein maps: update 1993'';'';''
Electrophoresis 14(1):1223-1231(1993)
2D PAGE maps for identified proteins
How to interpret a protein

RBC_HUMAN {Red blood cells}
Homo sapiens (Human)
Tissue: Erythrocyte
RBC_HUMAN
  map experimental info
  protein estimated location
 
RBC_HUMAN

MAP LOCATIONS:
pI=6.62; Mw=31524
pI=6.76; Mw=31524
pI=6.94; Mw=31524

MAPPING (identification):
MICROSEQUENCING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP21108; PRPS3_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePRPS3_HUMAN
Primary accession numberP21108
Secondary accession number(s) Q6P5P6
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on September 21, 2011 (version 102)
Name and origin of the protein
DescriptionRecName: Full=Ribose-phosphate pyrophosphokinase 3; EC=2.7.6.1; AltName: Full=Phosphoribosyl pyrophosphate synthase 1-like 1; Short=PRPS1-like 1; AltName: Full=Phosphoribosyl pyrophosphate synthase III; Short=PRS-III;
Gene nameName=PRPS1L1
Synonyms=PRPS3, PRPSL
Encoded onName=PRPS1L1; Synonyms=PRPS3, PRPSL
KeywordsAcetylation; ATP-binding; Complete proteome; Direct protein sequencing; Kinase; Magnesium; Metal-binding; Nucleotide biosynthesis; Nucleotide-binding; Polymorphism; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM57423; AAB59463.1; -; mRNA
EMBLBC062797; AAH62797.2; -; mRNA
IPIIPI00218371; -; .
PIRA37893; KIHUR3; .
RefSeqNP_787082.1; NM_175886.2; .
UniGeneHs.169284; -; .
ProteinModelPortalP21108; -; .
SMRP21108; 3-313; .
STRINGP21108; -; .
PhosphoSiteP21108; -; .
SWISS-2DPAGEP21108; -; .
PRIDEP21108; -; .
EnsemblENST00000430993; ENSP00000390134; ENSG00000229937; .
GeneID221823; -; .
KEGGhsa:221823; -; .
NMPDRfig|9606.3.peg.28305; -; .
UCSCuc003stz.1; human; .
CTD221823; -; .
GeneCardsGC07M018032; -; .
H-InvDBHIX0033604; -; .
HGNCHGNC:9463; PRPS1L1; .
MIM611566; gene; .
neXtProtNX_P21108; -; .
PharmGKBPA33818; -; .
eggNOGprNOG18675; -; .
GeneTreeENSGT00550000074583; -; .
HOGENOMHBG519284; -; .
HOVERGENHBG001520; -; .
InParanoidP21108; -; .
PhylomeDBP21108; -; .
ReactomeREACT_474; Metabolism of carbohydrates; .
NextBio91465; -; .
ArrayExpressP21108; -; .
CleanExHS_PRPS1L1; -; .
GenevestigatorP21108; -; .
GermOnlineENSG00000153287; Homo sapiens; .
GOGO:0005524; F:ATP binding; ISS:UniProtKB; .
GOGO:0016301; F:kinase activity; IEA:UniProtKB-KW; .
GOGO:0000287; F:magnesium ion binding; IEA:InterPro; .
GOGO:0042803; F:protein homodimerization activity; ISS:UniProtKB; .
GOGO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB; .
GOGO:0009116; P:nucleoside metabolic process; IEA:InterPro; .
GOGO:0009156; P:ribonucleoside monophosphate biosynthetic process; NAS:UniProtKB; .
InterProIPR000842; PRib_PP_synth_CS; .
InterProIPR000836; PRibTrfase; .
InterProIPR005946; Rib-P_diPkinase; .
PfamPF00156; Pribosyltran; 1; .
TIGRFAMsTIGR01251; RibP_PPkin; 1; .
PROSITEPS00114; PRPP_SYNTHASE; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server