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Searching in 'SWISS-2DPAGE' for entry matching: Q02566



General information about the entry
View entry in simple text format
Entry nameMYH6_MOUSE
Primary accession numberQ02566
integrated into SWISS-2DPAGE on October 31, 1999 (release 11)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Myosin-6; AltName: Full=Myosin heavy chain 6; AltName: Full=Myosin heavy chain, cardiac muscle alpha isoform; Short=MyHC-alpha;.
Gene nameName=Myh6
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
  map experimental info
  protein estimated location

pI=5.27; Mw=141926  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtQ02566; MYH6_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameMYH6_MOUSE
Primary accession numberQ02566
Secondary accession number(s) Q64258 Q64738
Sequence was last modified on July 15, 1998 (version 2)
Annotations were last modified on September 21, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Myosin-6; AltName: Full=Myosin heavy chain 6; AltName: Full=Myosin heavy chain, cardiac muscle alpha isoform; Short=MyHC-alpha;
Gene nameName=Myh6
Encoded onName=Myh6; Synonyms=Myhca
KeywordsActin-binding; ATP-binding; Calmodulin-binding; Coiled coil; Complete proteome; Cytoplasm; Isopeptide bond; Methylation; Motor protein; Muscle protein; Myosin; Nucleotide-binding; Polymorphism; Reference proteome; Thick filament; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM76598; AAA37159.1; -; mRNA
EMBLM76599; AAA37160.1; -; mRNA
EMBLM76600; AAA37161.1; -; mRNA
EMBLM76601; AAA37162.1; -; mRNA
EMBLM62404; AAA37424.1; -; Genomic_DNA
IPIIPI00129404; -; .
PIRI49464; I49464; .
RefSeqNP_001157643.1; NM_001164171.1; .
RefSeqNP_034986.1; NM_010856.4; .
UniGeneMm.290003; -; .
ProteinModelPortalQ02566; -; .
SMRQ02566; 3-843; 852-963; .
IntActQ02566; 1; .
STRINGQ02566; -; .
PhosphoSiteQ02566; -; .
SWISS-2DPAGEQ02566; -; .
PRIDEQ02566; -; .
EnsemblENSMUST00000081857; ENSMUSP00000080538; ENSMUSG00000040752; .
GeneID17888; -; .
KEGGmmu:17888; -; .
CTD4624; -; .
MGIMGI:97255; Myh6; .
eggNOGmaNOG18254; -; .
HOGENOMHBG717149; -; .
HOVERGENHBG004704; -; .
InParanoidQ02566; -; .
PhylomeDBQ02566; -; .
NextBio292705; -; .
ArrayExpressQ02566; -; .
BgeeQ02566; -; .
GenevestigatorQ02566; -; .
GermOnlineENSMUSG00000040752; Mus musculus; .
GOGO:0032982; C:myosin filament; IEA:UniProtKB-KW; .
GOGO:0001725; C:stress fiber; IDA:MGI; .
GOGO:0030018; C:Z disc; IDA:MGI; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0005516; F:calmodulin binding; IEA:UniProtKB-KW; .
GOGO:0000146; F:microfilament motor activity; IMP:MGI; .
GOGO:0007512; P:adult heart development; IMP:MGI; .
GOGO:0030509; P:BMP signaling pathway; IDA:MGI; .
GOGO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI; .
GOGO:0048739; P:cardiac muscle fiber development; IMP:MGI; .
GOGO:0001701; P:in utero embryonic development; IMP:MGI; .
GOGO:0043462; P:regulation of ATPase activity; IMP:MGI; .
GOGO:0008217; P:regulation of blood pressure; IMP:MGI; .
GOGO:0002027; P:regulation of heart rate; IMP:MGI; .
GOGO:0002026; P:regulation of the force of heart contraction; IMP:MGI; .
GOGO:0045214; P:sarcomere organization; IMP:MGI; .
GOGO:0006941; P:striated muscle contraction; IMP:MGI; .
GOGO:0007522; P:visceral muscle development; IMP:MGI; .
InterProIPR000048; IQ_motif_EF-hand-BS; .
InterProIPR015650; Myosin_hc; .
InterProIPR001609; Myosin_head_motor_dom; .
InterProIPR004009; Myosin_N; .
InterProIPR002928; Myosin_tail; .
PANTHERPTHR13140:SF22; Myosin_hc; 1; .
PfamPF00063; Myosin_head; 1; .
PfamPF02736; Myosin_N; 1; .
PfamPF01576; Myosin_tail_1; 1; .
SMARTSM00015; IQ; 2; .
SMARTSM00242; MYSc; 1; .
PROSITEPS50096; IQ; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server