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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: Q13185



General information about the entry
View entry in simple text format
Entry nameCBX3_HUMAN
Primary accession numberQ13185
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Chromobox protein homolog 3; AltName: Full=HECH; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma; AltName: Full=Modifier 2 protein;.
Gene nameName=CBX3
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

pI=5.27; Mw=22283  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtQ13185; CBX3_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCBX3_HUMAN
Primary accession numberQ13185
Secondary accession number(s) Q96CD7 Q99409 Q9BVS3 Q9P0Z6
Sequence was last modified on October 17, 2006 (version 4)
Annotations were last modified on October 19, 2011 (version 125)
Name and origin of the protein
DescriptionRecName: Full=Chromobox protein homolog 3; AltName: Full=HECH; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma; AltName: Full=Modifier 2 protein;
Gene nameName=CBX3
Encoded onName=CBX3
Keywords3D-structure; Acetylation; Chromatin regulator; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU26312; AAB48101.1; -; mRNA
EMBLAB030905; BAA83340.1; -; mRNA
EMBLAF136630; AAF62370.1; -; mRNA
EMBLBC000954; AAH00954.1; -; mRNA
EMBLBC014380; AAH14380.1; -; mRNA
IPIIPI00297579; -; .
RefSeqNP_009207.2; NM_007276.4; .
RefSeqNP_057671.2; NM_016587.3; .
UniGeneHs.381189; -; .
PDB2L11; NMR; -; A=29-81
PDB3DM1; X-ray; 2.40 A; A/C/E/G=29-86
PDB3KUP; X-ray; 1.77 A; A/B/C/D=110-173
PDBsum2L11; -; .
PDBsum3DM1; -; .
PDBsum3KUP; -; .
ProteinModelPortalQ13185; -; .
SMRQ13185; 29-81; 112-173; .
DIPDIP-5985N; -; .
IntActQ13185; 11; .
MINTMINT-5002782; -; .
STRINGQ13185; -; .
PhosphoSiteQ13185; -; .
SWISS-2DPAGEQ13185; -; .
PeptideAtlasQ13185; -; .
PRIDEQ13185; -; .
EnsemblENST00000337620; ENSP00000336687; ENSG00000122565; .
EnsemblENST00000396386; ENSP00000379670; ENSG00000122565; .
GeneID11335; -; .
KEGGhsa:11335; -; .
UCSCuc003sxt.1; human; .
CTD11335; -; .
GeneCardsGC07P026207; -; .
H-InvDBHIX0006535; -; .
HGNCHGNC:1553; CBX3; .
HPACAB001973; -; .
HPAHPA004902; -; .
MIM604477; gene; .
neXtProtNX_Q13185; -; .
GeneTreeENSGT00510000046310; -; .
HOGENOMHBG314523; -; .
HOVERGENHBG000400; -; .
InParanoidQ13185; -; .
OrthoDBEOG4N30QB; -; .
PhylomeDBQ13185; -; .
NextBio43065; -; .
ArrayExpressQ13185; -; .
BgeeQ13185; -; .
CleanExHS_CBX3; -; .
GenevestigatorQ13185; -; .
GermOnlineENSG00000122565; Homo sapiens; .
GOGO:0000779; C:condensed chromosome; centromeric region; ISS:UniProtKB
GOGO:0031618; C:nuclear centromeric heterochromatin; ISS:UniProtKB; .
GOGO:0005719; C:nuclear euchromatin; IDA:UniProtKB; .
GOGO:0005637; C:nuclear inner membrane; NAS:UniProtKB; .
GOGO:0005819; C:spindle; IDA:UniProtKB; .
GOGO:0019899; F:enzyme binding; IPI:UniProtKB; .
GOGO:0019904; F:protein domain specific binding; IPI:UniProtKB; .
GOGO:0006338; P:chromatin remodeling; NAS:UniProtKB; .
GOGO:0045892; P:negative regulation of transcription; DNA-dependent; IDA:UniProtKB
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterProIPR017984; Chromo_dom_subgr; .
InterProIPR023780; Chromo_domain; .
InterProIPR000953; Chromo_domain/shadow; .
InterProIPR008251; Chromo_shadow; .
InterProIPR018125; Chromo_shadow_sbgrp; .
InterProIPR016197; Chromodomain-like; .
InterProIPR023779; Chromodomain_CS; .
PfamPF00385; Chromo; 1; .
PfamPF01393; Chromo_shadow; 1; .
SMARTSM00298; CHROMO; 2; .
SMARTSM00300; ChSh; 1; .
SUPFAMSSF54160; Chromodomain-like; 2; .
PROSITEPS00598; CHROMO_1; 1; .
PROSITEPS50013; CHROMO_2; 2; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server