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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: Q60610



General information about the entry
View entry in simple text format
Entry nameTIAM1_MOUSE
Primary accession numberQ60610
integrated into SWISS-2DPAGE on June 30, 1999 (release 10)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=T-lymphoma invasion and metastasis-inducing protein 1; Short=TIAM-1;.
Gene nameName=Tiam1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
  map experimental info
  protein estimated location

pI=6.07; Mw=172342  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtQ60610; TIAM1_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTIAM1_MOUSE
Primary accession numberQ60610
Sequence was last modified on November 1, 1996 (version 1)
Annotations were last modified on October 19, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=T-lymphoma invasion and metastasis-inducing protein 1; Short=TIAM-1;
Gene nameName=Tiam1
Encoded onName=Tiam1; Synonyms=Tiam-1
Keywords3D-structure; Cell junction; Complete proteome; Guanine-nucleotide releasing factor; Lipoprotein; Myristate; Phosphoprotein; Reference proteome; Repeat.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU05245; AAA18830.1; -; mRNA
IPIIPI00119006; -; .
PIRA54146; A54146; .
UniGeneMm.310902; -; .
PDB1FOE; X-ray; 2.80 A; A/C/E/G=1033-1406
PDB3A8N; X-ray; 4.50 A; A=429-702
PDBsum1FOE; -; .
PDBsum3A8N; -; .
ProteinModelPortalQ60610; -; .
SMRQ60610; 433-670; 835-935; 1034-1401
IntActQ60610; 1; .
STRINGQ60610; -; .
PhosphoSiteQ60610; -; .
SWISS-2DPAGEQ60610; -; .
PRIDEQ60610; -; .
UCSCuc007zvu.2; mouse; .
MGIMGI:103306; Tiam1; .
GeneTreeENSGT00600000084055; -; .
HOGENOMHBG506823; -; .
HOVERGENHBG059279; -; .
InParanoidQ60610; -; .
OrthoDBEOG49CQ6T; -; .
NextBio301314; -; .
PMAP-CutDBQ60610; -; .
ArrayExpressQ60610; -; .
BgeeQ60610; -; .
CleanExMM_TIAM1; -; .
GenevestigatorQ60610; -; .
GermOnlineENSMUSG00000002489; Mus musculus; .
GOGO:0005911; C:cell-cell junction; ISS:UniProtKB; .
GOGO:0005622; C:intracellular; IEA:InterPro; .
GOGO:0005057; F:receptor signaling protein activity; IEA:InterPro; .
GOGO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro; .
GOGO:0035556; P:intracellular signal transduction; IEA:InterPro; .
GOGO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro; .
InterProIPR000219; DH-domain; .
InterProIPR001331; GDS_CDC24_CS; .
InterProIPR001478; PDZ/DHR/GLGF; .
InterProIPR011993; PH_type; .
InterProIPR001849; Pleckstrin_homology; .
InterProIPR003116; Raf-like_ras-bd; .
Gene3DG3DSA:; PH_type; 2; .
Gene3DG3DSA:1.20.900.10; RhoGEF; 1; .
PfamPF00595; PDZ; 1; .
PfamPF00169; PH; 1; .
PfamPF02196; RBD; 1; .
PfamPF00621; RhoGEF; 1; .
SMARTSM00228; PDZ; 1; .
SMARTSM00233; PH; 2; .
SMARTSM00455; RBD; 1; .
SMARTSM00325; RhoGEF; 1; .
SUPFAMSSF48065; DH-domain; 1; .
SUPFAMSSF50156; PDZ; 1; .
PROSITEPS00741; DH_1; 1; .
PROSITEPS50010; DH_2; 1; .
PROSITEPS50106; PDZ; 1; .
PROSITEPS50898; RBD; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server