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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: RL21_HUMAN




SWISS-2DPAGE:  RL21_HUMAN


RL21_HUMAN


General information about the entry
View entry in simple text format
Entry nameRL21_HUMAN
Primary accession numberP46778
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L21;.
Gene nameName=RPL21
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=23274  [identification data]
Mw=22406  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP46778; RL21_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRL21_HUMAN
Primary accession numberP46778
Secondary accession number(s) Q16699
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 121)
Name and origin of the protein
DescriptionRecName: Full=60S ribosomal protein L21;
Gene nameName=RPL21
Encoded onName=RPL21
KeywordsComplete proteome; Direct protein sequencing; Disease mutation; Hypotrichosis; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX89401; CAA61582.1; -; mRNA
EMBLU14967; AAA85655.1; -; mRNA
EMBLAB061826; BAB79464.1; -; Genomic_DNA
EMBLBC001603; AAH01603.1; -; mRNA
EMBLBC007505; AAH07505.1; -; mRNA
EMBLBC062981; AAH62981.1; -; mRNA
EMBLBC070184; AAH70184.1; -; mRNA
EMBLBC070323; AAH70323.1; -; mRNA
EMBLBC070330; AAH70330.1; -; mRNA
EMBLU25789; AAA93231.1; -; mRNA
EMBLL38826; AAA80462.1; -; Genomic_DNA
EMBLAB007176; BAA25835.1; -; Genomic_DNA
IPIIPI00247583; -; .
PIRS55913; S55913; .
RefSeqNP_000973.2; NM_000982.3; .
UniGeneHs.381123; -; .
UniGeneHs.535873; -; .
ProteinModelPortalP46778; -; .
SMRP46778; 4-99; .
IntActP46778; 18; .
STRINGP46778; -; .
PhosphoSiteP46778; -; .
SWISS-2DPAGEP46778; -; .
PRIDEP46778; -; .
EnsemblENST00000272274; ENSP00000351021; ENSG00000122026; .
EnsemblENST00000311549; ENSP00000346027; ENSG00000122026; .
EnsemblENST00000319826; ENSP00000370574; ENSG00000122026; .
EnsemblENST00000326092; ENSP00000370569; ENSG00000122026; .
GeneID6144; -; .
KEGGhsa:6144; -; .
UCSCuc001ura.1; human; .
CTD6144; -; .
H-InvDBHIX0032888; -; .
H-InvDBHIX0056900; -; .
H-InvDBHIX0096689; -; .
HGNCHGNC:10313; RPL21; .
MIM603636; gene; .
neXtProtNX_P46778; -; .
PharmGKBPA34683; -; .
eggNOGprNOG12825; -; .
HOVERGENHBG001518; -; .
InParanoidP46778; -; .
OMAGNILPKR; -; .
OrthoDBEOG4K6G5D; -; .
PhylomeDBP46778; -; .
ReactomeREACT_13698; Regulation of beta-cell development; .
ReactomeREACT_15380; Diabetes pathways; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_1762; 3' -UTR-mediated translational regulation; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_6167; Influenza Infection; .
ReactomeREACT_71; Gene Expression; .
NextBio23871; -; .
BgeeP46778; -; .
CleanExHS_RPL21; -; .
GenevestigatorP46778; -; .
GermOnlineENSG00000122026; Homo sapiens; .
GOGO:0022625; C:cytosolic large ribosomal subunit; TAS:ProtInc; .
GOGO:0003723; F:RNA binding; TAS:ProtInc; .
GOGO:0003735; F:structural constituent of ribosome; TAS:ProtInc; .
GOGO:0031018; P:endocrine pancreas development; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0006414; P:translational elongation; TAS:Reactome; .
GOGO:0006415; P:translational termination; TAS:Reactome; .
GOGO:0019083; P:viral transcription; TAS:Reactome; .
InterProIPR001147; Ribosomal_L21e; .
InterProIPR018259; Ribosomal_L21e_CS; .
InterProIPR008991; Translation_prot_SH3-like; .
PANTHERPTHR20981; Ribosomal_L21e; 1; .
PfamPF01157; Ribosomal_L21e; 1; .
SUPFAMSSF50104; Transl_SH3_like; 1; .
PROSITEPS01171; RIBOSOMAL_L21E; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server