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SWISS-2DPAGE

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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: RLA2_HUMAN




SWISS-2DPAGE:  RLA2_HUMAN


RLA2_HUMAN


General information about the entry
View entry in simple text format
Entry nameRLA2_HUMAN
Primary accession numberP05387
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 16)
Name and origin of the protein
DescriptionRecName: Full=60S acidic ribosomal protein P2; AltName: Full=Renal carcinoma antigen NY-REN-44;.
Gene nameName=RPLP2
Synonyms=D11S2243E, RPP2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=97295305; PubMed=9150947; [NCBI, Expasy, EBI, Israel, Japan]
Sarto C., Marocchi A., Sanchez J.-C., Giannone D., Frutiger S., Golaz O., Wilkins M.R., Doro G., Cappellano F., Hughes G.J., Hochstrasser D.F., Mocarelli P.
''''''Renal cell carcinoma and normal kidney protein expression'';'';''
Electrophoresis 18(1):599-604(1997)
[3]   MAPPING ON GEL
Tonella L., Hoogland C., Appel R.D., Sanchez J.-C., Hochstrasser D.F.
Submitted (JUL-1997) to SWISS-2DPAGE
[4]   MAPPING ON GEL
MEDLINE=96314065; PubMed=8740185; [NCBI, Expasy, EBI, Israel, Japan]
Lutomski D., Caron M., Cornillot J.D., Bourin P., Dupuy C., Pontet M., Bladier D., Joubert-Caron R.
''''''Identification of different galectins by immunoblotting after two- dimensional polyacrylamide get electrophoresis with immobilized pH gradients'';'';''
Electrophoresis 17(1):600-606(1996)
Comments
  • SUBUNIT: DIMER P1 AND P2
2D PAGE maps for identified proteins
How to interpret a protein

HL60_HUMAN {Promyelocytic leukemia cells}
Homo sapiens (Human)
Tissue: Promyelocytic leukemia
HL60_HUMAN
  map experimental info
  protein estimated location
 
HL60_HUMAN

MAP LOCATIONS:
pI=4.28; Mw=12956

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [3][4].



KIDNEY_HUMAN {Kidney}
Homo sapiens (Human)
Tissue: Kidney
KIDNEY_HUMAN
  map experimental info
  protein estimated location
 
KIDNEY_HUMAN

MAP LOCATIONS:
pI=4.40; Mw=14034

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=4.38; Mw=13616

MAPPING (identification):
MICROSEQUENCING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
PHCI-2DPAGEP05387; RLA2_HUMAN.
UniProtKB/Swiss-ProtP05387; RLA2_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRLA2_HUMAN
Primary accession numberP05387
Sequence was last modified on November 1, 1988 (version 1)
Annotations were last modified on October 19, 2011 (version 132)
Name and origin of the protein
DescriptionRecName: Full=60S acidic ribosomal protein P2; AltName: Full=Renal carcinoma antigen NY-REN-44;
Gene nameName=RPLP2
Synonyms=D11S2243E, RPP2
Encoded onName=RPLP2; Synonyms=D11S2243E, RPP2
Keywords3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM17887; AAA36472.1; -; mRNA
EMBLAB061837; BAB79475.1; -; Genomic_DNA
EMBLBC005354; AAH05354.1; -; mRNA
EMBLBC005920; AAH05920.1; -; mRNA
EMBLBC007573; AAH07573.1; -; mRNA
EMBLBC062314; AAH62314.1; -; mRNA
IPIIPI00008529; -; .
PIRC27125; R6HUP2; .
RefSeqNP_000995.1; NM_001004.3; .
UniGeneHs.437594; -; .
PDB1S4J; NMR; -; A=103-115
PDB2JDL; X-ray; 2.20 A; C/D=105-115
PDB2W1O; NMR; -; A/B=1-69
PDBsum1S4J; -; .
PDBsum2JDL; -; .
PDBsum2W1O; -; .
ProteinModelPortalP05387; -; .
SMRP05387; 1-69; .
IntActP05387; 13; .
MINTMINT-4999550; -; .
STRINGP05387; -; .
Allergome1276; Hom s P2; .
PhosphoSiteP05387; -; .
SWISS-2DPAGEP05387; -; .
PHCI-2DPAGEP05387; -; .
PeptideAtlasP05387; -; .
PRIDEP05387; -; .
EnsemblENST00000321153; ENSP00000322419; ENSG00000177600; .
GeneID6181; -; .
KEGGhsa:6181; -; .
UCSCuc001lrq.1; human; .
CTD6181; -; .
GeneCardsGC11P000625; -; .
H-InvDBHIX0018031; -; .
H-InvDBHIX0200997; -; .
HGNCHGNC:10377; RPLP2; .
MIM180530; gene; .
neXtProtNX_P05387; -; .
PharmGKBPA34776; -; .
eggNOGprNOG21412; -; .
HOGENOMHBG744999; -; .
HOVERGENHBG014761; -; .
InParanoidP05387; -; .
OMAAVLGGNE; -; .
OrthoDBEOG4F4SCS; -; .
PhylomeDBP05387; -; .
ReactomeREACT_13698; Regulation of beta-cell development; .
ReactomeREACT_15380; Diabetes pathways; .
ReactomeREACT_17015; Metabolism of proteins; .
ReactomeREACT_1762; 3' -UTR-mediated translational regulation; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_6167; Influenza Infection; .
ReactomeREACT_71; Gene Expression; .
NextBio24001; -; .
ArrayExpressP05387; -; .
BgeeP05387; -; .
CleanExHS_RPLP2; -; .
GenevestigatorP05387; -; .
GermOnlineENSG00000177600; Homo sapiens; .
GOGO:0022625; C:cytosolic large ribosomal subunit; TAS:ProtInc; .
GOGO:0003723; F:RNA binding; TAS:ProtInc; .
GOGO:0003735; F:structural constituent of ribosome; TAS:ProtInc; .
GOGO:0031018; P:endocrine pancreas development; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0006414; P:translational elongation; TAS:Reactome; .
GOGO:0006415; P:translational termination; TAS:Reactome; .
GOGO:0019083; P:viral transcription; TAS:Reactome; .
InterProIPR001813; Ribosomal_60S; .
PfamPF00428; Ribosomal_60s; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server