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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: RM12_HUMAN




SWISS-2DPAGE:  RM12_HUMAN


RM12_HUMAN


General information about the entry
View entry in simple text format
Entry nameRM12_HUMAN
Primary accession numberP52815
integrated into SWISS-2DPAGE on September 1, 1997 (release 6)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 13)
Name and origin of the protein
DescriptionRecName: Full=39S ribosomal protein L12, mitochondrial; Short=L12mt; Short=MRP-L12; AltName: Full=5c5-2; Flags: Precursor;.
Gene nameName=MRPL12
Synonyms=RPML12
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=98163346; PubMed=9504818; [NCBI, Expasy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.
''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';''
Electrophoresis 18(1):2842-2848(1997)
[2]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

CEC_HUMAN {Colorectal epithelia cells}
Homo sapiens (Human)
Tissue: Colon epithelium
CEC_HUMAN
  map experimental info
  protein estimated location
 
CEC_HUMAN

MAP LOCATIONS:
pI=5.01; Mw=17498

MAPPING (identification):
MICROSEQUENCING [1].



DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=5.08; Mw=17837  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP52815; P52815.
DOSAC-COBS-2DPAGEP52815; RM12_HUMAN.
UniProtKB/Swiss-ProtP52815; RM12_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameRM12_HUMAN
Primary accession numberP52815
Secondary accession number(s) Q969U0 Q9HCA2 Q9UQJ3
Sequence was last modified on May 15, 2002 (version 2)
Annotations were last modified on October 19, 2011 (version 111)
Name and origin of the protein
DescriptionRecName: Full=39S ribosomal protein L12, mitochondrial; Short=L12mt; Short=MRP-L12; AltName: Full=5c5-2; Flags: Precursor;
Gene nameName=MRPL12
Synonyms=RPML12
Encoded onName=MRPL12; Synonyms=RPML12
KeywordsComplete proteome; Mitochondrion; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX79865; CAA56249.1; -; mRNA
EMBLAF059736; AAG32154.1; -; Genomic_DNA
EMBLBC002344; AAH02344.1; -; mRNA
EMBLBC007497; AAH07497.1; -; mRNA
EMBLAF105278; AAD16894.1; ALT_FRAME; mRNA
IPIIPI01015060; -; .
RefSeqNP_002940.2; NM_002949.3; .
UniGeneHs.109059; -; .
ProteinModelPortalP52815; -; .
SMRP52815; 64-198; .
IntActP52815; 4; .
MINTMINT-1150069; -; .
STRINGP52815; -; .
SWISS-2DPAGEP52815; -; .
DOSAC-COBS-2DPAGEP52815; -; .
PeptideAtlasP52815; -; .
PRIDEP52815; -; .
EnsemblENST00000333676; ENSP00000333837; ENSG00000183093; .
GeneID6182; -; .
KEGGhsa:6182; -; .
UCSCuc002kbh.1; human; .
CTD6182; -; .
GeneCardsGC17P075116; -; .
HGNCHGNC:10378; MRPL12; .
HPAHPA022853; -; .
HPAHPA023043; -; .
MIM602375; gene; .
neXtProtNX_P52815; -; .
PharmGKBPA30941; -; .
eggNOGprNOG16405; -; .
HOGENOMHBG746222; -; .
HOVERGENHBG001832; -; .
InParanoidP52815; -; .
OMAAPVMAMP; -; .
OrthoDBEOG4R5044; -; .
PhylomeDBP52815; -; .
NextBio24005; -; .
ArrayExpressP52815; -; .
BgeeP52815; -; .
CleanExHS_MRPL12; -; .
GenevestigatorP52815; -; .
GermOnlineENSG00000183093; Homo sapiens; .
GOGO:0005762; C:mitochondrial large ribosomal subunit; IDA:UniProtKB; .
GOGO:0005515; F:protein binding; IPI:HGNC; .
GOGO:0003723; F:RNA binding; TAS:ProtInc; .
GOGO:0003735; F:structural constituent of ribosome; TAS:ProtInc; .
GOGO:0045893; P:positive regulation of transcription; DNA-dependent; IDA:HGNC
GOGO:0006390; P:transcription from mitochondrial promoter; IDA:HGNC; .
GOGO:0006412; P:translation; IEA:InterPro; .
InterProIPR015607; Ribosomal_L12_mit; .
InterProIPR014719; Ribosomal_L7/12_C/ClpS-like; .
InterProIPR013823; Ribosomal_L7/L12_C; .
InterProIPR008932; Ribosomal_L7/L12_oligo; .
Gene3DG3DSA:3.30.1390.10; Ribosomal_L7/12_C/ClpS-like; 1; .
PANTHERPTHR11809:SF2; Ribosomal_L12_mit; 1; .
PfamPF00542; Ribosomal_L12; 1; .
ProDomPD001326; Ribosomal_L7/L12_C; 1; .
SUPFAMSSF48300; Ribosomal_L12/7; 1; .
SUPFAMSSF54736; Ribosomal_L7/12_C/ClpS-like; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server