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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: ROAA_HUMAN



General information about the entry
View entry in simple text format
Entry nameROAA_HUMAN
Primary accession numberQ99729
Secondary accession number(s) Q9BQ99
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein A/B; Short=hnRNP A/B; AltName: Full=APOBEC1-binding protein 1; Short=ABBP-1;.
Gene nameName=HNRNPAB
Synonyms=ABBP1, HNRPAB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=42121  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtQ99729; ROAA_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameROAA_HUMAN
Primary accession numberQ99729
Secondary accession number(s) B3KNN5 D3DWP7 Q04150 Q8N7U3 Q9BQ99
Sequence was last modified on September 11, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 107)
Name and origin of the protein
DescriptionRecName: Full=Heterogeneous nuclear ribonucleoprotein A/B; Short=hnRNP A/B; AltName: Full=APOBEC1-binding protein 1; Short=ABBP-1;
Gene nameName=HNRNPAB
Synonyms=ABBP1, HNRPAB
Encoded onName=HNRNPAB; Synonyms=ABBP1, HNRPAB
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM65028; AAA36575.1; ALT_FRAME; mRNA
EMBLU76713; AAC50956.1; ALT_FRAME; mRNA
EMBLAK054600; BAG51397.1; -; mRNA
EMBLAK097657; BAC05134.1; -; mRNA
EMBLCH471165; EAW53843.1; -; Genomic_DNA
EMBLCH471165; EAW53844.1; -; Genomic_DNA
EMBLCH471165; EAW53845.1; -; Genomic_DNA
EMBLBC001616; AAH01616.1; -; mRNA
EMBLBC002625; AAH02625.1; -; mRNA
EMBLBC004561; AAH04561.1; -; mRNA
EMBLBC009359; AAH09359.1; -; mRNA
EMBLBC036708; AAH36708.1; -; mRNA
IPIIPI00106509; -; .
IPIIPI00329355; -; .
IPIIPI00334587; -; .
IPIIPI00334713; -; .
PIRS17563; S17563; .
RefSeqNP_004490.2; NM_004499.3; .
RefSeqNP_112556.2; NM_031266.2; .
UniGeneHs.591731; -; .
UniGeneHs.715055; -; .
PDB3S7R; X-ray; 2.15 A; A/B=59-144
PDBsum3S7R; -; .
ProteinModelPortalQ99729; -; .
SMRQ99729; 66-233; .
IntActQ99729; 16; .
MINTMINT-4537784; -; .
STRINGQ99729; -; .
PhosphoSiteQ99729; -; .
SWISS-2DPAGEQ99729; -; .
PRIDEQ99729; -; .
EnsemblENST00000358344; ENSP00000351108; ENSG00000197451; .
GeneID3182; -; .
KEGGhsa:3182; -; .
UCSCuc003miu.1; human; .
UCSCuc003miv.1; human; .
CTD3182; -; .
GeneCardsGC05P172357; -; .
MIM602688; gene; .
neXtProtNX_Q99729; -; .
PharmGKBPA162391196; -; .
eggNOGprNOG14512; -; .
GeneTreeENSGT00560000076532; -; .
HOGENOMHBG756718; -; .
HOVERGENHBG002295; -; .
InParanoidQ99729; -; .
OrthoDBEOG42BX9K; -; .
NextBio12628; -; .
ArrayExpressQ99729; -; .
BgeeQ99729; -; .
CleanExHS_HNRNPAB; -; .
GenevestigatorQ99729; -; .
GermOnlineENSG00000197451; Homo sapiens; .
GOGO:0005737; C:cytoplasm; ISS:HGNC; .
GOGO:0005634; C:nucleus; ISS:HGNC; .
GOGO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB; .
GOGO:0003729; F:mRNA binding; TAS:ProtInc; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0001837; P:epithelial to mesenchymal transition; ISS:HGNC; .
GOGO:0045893; P:positive regulation of transcription; DNA-dependent; ISS:HGNC
GOGO:0006351; P:transcription; DNA-dependent; ISS:GOC
InterProIPR012956; CARG-binding_factor_N; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
Gene3DG3DSA:; a_b_plait_nuc_bd; 2; .
PfamPF08143; CBFNT; 1; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
PROSITEPS50102; RRM; 2; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server