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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: SAMP_HUMAN




SWISS-2DPAGE:  SAMP_HUMAN


SAMP_HUMAN


General information about the entry
View entry in simple text format
Entry nameSAMP_HUMAN
Primary accession numberP02743
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Serum amyloid P-component; Short=SAP; AltName: Full=9.5S alpha-1-glycoprotein; Contains: RecName: Full=Serum amyloid P-component(1-203); Flags: Precursor;.
Gene nameName=APCS
Synonyms=PTX2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=94147970; PubMed=8313871; [NCBI, Expasy, EBI, Israel, Japan]
Golaz O., Hughes G.J., Frutiger S., Paquet N., Bairoch A., Pasquali C., Sanchez J.-C., Tissot J.-D., Appel R.D., Walzer C., Balant L.P., Hochstrasser D.F.
''''''Plasma and red blood cell protein maps: update 1993'';'';''
Electrophoresis 14(1):1223-1231(1993)
Comments
  • SUBUNIT: HOMOPENTAMER
2D PAGE maps for identified proteins
How to interpret a protein

PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=5.55; Mw=26280

NORMAL LEVEL:
30-80 MG/L [1].

PATHOLOGICAL LEVEL:
DECREASED DURING LIVER CIRRHOSIS [1].

MAPPING (identification):
MICROSEQUENCING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP02743; P02743.
DOSAC-COBS-2DPAGEP02743; SAMP_HUMAN.
OGP-WWWP02743.
REPRODUCTION-2DPAGEIPI00022391; IPI00022391.
REPRODUCTION-2DPAGEP02743; P02743.
Siena-2DPAGEP02743; SAMP_HUMAN.
UniProtKB/Swiss-ProtP02743; SAMP_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameSAMP_HUMAN
Primary accession numberP02743
Sequence was last modified on February 1, 1995 (version 2)
Annotations were last modified on September 21, 2011 (version 140)
Name and origin of the protein
DescriptionRecName: Full=Serum amyloid P-component; Short=SAP; AltName: Full=9.5S alpha-1-glycoprotein; Contains: RecName: Full=Serum amyloid P-component(1-203); Flags: Precursor;
Gene nameName=APCS
Synonyms=PTX2
Encoded onName=APCS; Synonyms=PTX2
Keywords3D-structure; Acetylation; Amyloid; Calcium; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Lectin; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Secreted; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD00097; BAA00060.1; -; Genomic_DNA
EMBLM10944; AAA60302.1; -; mRNA
EMBLX04608; CAA28275.1; -; mRNA
EMBLCR450313; CAG29309.1; -; mRNA
EMBLAL445528; CAH73651.1; -; Genomic_DNA
EMBLBT006750; AAP35396.1; -; mRNA
EMBLBC007039; AAH07039.1; -; mRNA
EMBLBC007058; AAH07058.1; -; mRNA
IPIIPI00022391; -; .
PIRA25503; YLHUP; .
RefSeqNP_001630.1; NM_001639.3; .
UniGeneHs.507080; -; .
PDB1GYK; X-ray; 2.20 A; A/B/C/D/E=20-223
PDB1LGN; X-ray; 2.80 A; A/B/C/D/E=20-223
PDB1SAC; X-ray; 2.00 A; A/B/C/D/E=20-223
PDB2A3W; X-ray; 2.20 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=20-223
PDB2A3X; X-ray; 3.00 A; A/B/C/D/E/F/G/H/I/J=20-223
PDB2A3Y; X-ray; 2.00 A; A/B/C/D/E=20-223
PDB2W08; X-ray; 1.70 A; A/B/C/D/E=20-223
PDB3D5O; X-ray; 2.80 A; A/B/C/D/E=20-223
PDB3KQR; X-ray; 1.50 A; A/B/C/D/E=20-223
PDBsum1GYK; -; .
PDBsum1LGN; -; .
PDBsum1SAC; -; .
PDBsum2A3W; -; .
PDBsum2A3X; -; .
PDBsum2A3Y; -; .
PDBsum2W08; -; .
PDBsum3D5O; -; .
PDBsum3KQR; -; .
ProteinModelPortalP02743; -; .
SMRP02743; 20-223; .
IntActP02743; 1; .
STRINGP02743; -; .
TCDB1.C.92.1.2; pentraxin family; .
GlycoSuiteDBP02743; -; .
SWISS-2DPAGEP02743; -; .
Cornea-2DPAGEP02743; -; .
DOSAC-COBS-2DPAGEP02743; -; .
OGPP02743; -; .
REPRODUCTION-2DPAGEIPI00022391; -; .
REPRODUCTION-2DPAGEP02743; -; .
PeptideAtlasP02743; -; .
PRIDEP02743; -; .
EnsemblENST00000255040; ENSP00000255040; ENSG00000132703; .
GeneID325; -; .
KEGGhsa:325; -; .
UCSCuc001ftv.1; human; .
CTD325; -; .
GeneCardsGC01P130914; -; .
H-InvDBHIX0001200; -; .
HGNCHGNC:584; APCS; .
HPACAB007817; -; .
MIM104770; gene; .
neXtProtNX_P02743; -; .
PharmGKBPA24877; -; .
eggNOGprNOG11978; -; .
GeneTreeENSGT00550000074240; -; .
HOGENOMHBG716040; -; .
HOVERGENHBG005405; -; .
InParanoidP02743; -; .
OMAFTLCFRA; -; .
OrthoDBEOG4R23VS; -; .
PhylomeDBP02743; -; .
ReactomeREACT_75925; Amyloids; .
NextBio1333; -; .
ArrayExpressP02743; -; .
BgeeP02743; -; .
CleanExHS_APCS; -; .
GenevestigatorP02743; -; .
GermOnlineENSG00000132703; Homo sapiens; .
GOGO:0005615; C:extracellular space; IDA:BHF-UCL; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0005529; F:sugar binding; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; TAS:ProtInc; .
GOGO:0006953; P:acute-phase response; TAS:ProtInc; .
GOGO:0051131; P:chaperone-mediated protein complex assembly; TAS:ProtInc; .
GOGO:0006457; P:protein folding; TAS:ProtInc; .
InterProIPR008985; ConA-like_lec_gl; .
InterProIPR013320; ConA-like_subgrp; .
InterProIPR001759; Pentaxin; .
Gene3DG3DSA:2.60.120.200; ConA_like_subgrp; 1; .
PfamPF00354; Pentaxin; 1; .
PRINTSPR00895; PENTAXIN; .
SMARTSM00159; PTX; 1; .
SUPFAMSSF49899; ConA_like_lec_gl; 1; .
PROSITEPS00289; PENTAXIN; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server