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SWISS-2DPAGE

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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: SERA_MOUSE




SWISS-2DPAGE:  SERA_MOUSE


SERA_MOUSE


General information about the entry
View entry in simple text format
Entry nameSERA_MOUSE
Primary accession numberQ61753
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=D-3-phosphoglycerate dehydrogenase; Short=3-PGDH; EC=1.1.1.95; AltName: Full=A10;.
Gene nameName=Phgdh
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ISLETS_MOUSE {Pancreatic islet cells}
Mus musculus (Mouse)
Tissue: Pancreatic islet
ISLETS_MOUSE
  map experimental info
  protein estimated location
 
ISLETS_MOUSE

MAP LOCATIONS:
pI=6.13; Mw=56734  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
COMPLUYEAST-2DPAGEQ61753; SERA_MOUSE.
REPRODUCTION-2DPAGEQ61753; Q61753.
REPRODUCTION-2DPAGEIPI00228385; IPI00228385.
REPRODUCTION-2DPAGEIPI00225961; IPI00225961.
UniProtKB/Swiss-ProtQ61753; SERA_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameSERA_MOUSE
Primary accession numberQ61753
Secondary accession number(s) Q3TEE5 Q75SV9 Q8C603
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 106)
Name and origin of the protein
DescriptionRecName: Full=D-3-phosphoglycerate dehydrogenase; Short=3-PGDH; EC=1.1.1.95; AltName: Full=A10;
Gene nameName=Phgdh
Encoded onName=Phgdh
KeywordsAcetylation; Amino-acid biosynthesis; Complete proteome; Direct protein sequencing; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Serine biosynthesis.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAB128936; BAD08449.1; -; Genomic_DNA
EMBLAK076815; BAC36494.1; -; mRNA
EMBLAK169684; BAE41303.1; -; mRNA
EMBLBC086668; AAH86668.1; -; mRNA
EMBLBC110673; AAI10674.1; -; mRNA
EMBLL21027; AAB67986.1; -; mRNA
IPIIPI00225961; -; .
RefSeqNP_058662.2; NM_016966.3; .
UniGeneMm.16898; -; .
UniGeneMm.371997; -; .
ProteinModelPortalQ61753; -; .
SMRQ61753; 6-517; .
IntActQ61753; 2; .
STRINGQ61753; -; .
PhosphoSiteQ61753; -; .
SWISS-2DPAGEQ61753; -; .
COMPLUYEAST-2DPAGEQ61753; -; .
REPRODUCTION-2DPAGEIPI00225961; -; .
REPRODUCTION-2DPAGEQ61753; -; .
PRIDEQ61753; -; .
EnsemblENSMUST00000065793; ENSMUSP00000064755; ENSMUSG00000053398; .
GeneID236539; -; .
KEGGmmu:236539; -; .
NMPDRfig|10090.3.peg.26255; -; .
UCSCuc008qps.1; mouse; .
CTD26227; -; .
MGIMGI:1355330; Phgdh; .
eggNOGroNOG06496; -; .
GeneTreeENSGT00530000063021; -; .
HOGENOMHBG731446; -; .
HOVERGENHBG054241; -; .
InParanoidQ61753; -; .
OMATGVFDGY; -; .
OrthoDBEOG4Q2DF9; -; .
PhylomeDBQ61753; -; .
NextBio382995; -; .
ArrayExpressQ61753; -; .
BgeeQ61753; -; .
CleanExMM_PHGDH; -; .
GenevestigatorQ61753; -; .
GermOnlineENSMUSG00000053398; Mus musculus; .
GOGO:0051287; F:NAD binding; IEA:InterPro; .
GOGO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:MGI; .
GOGO:0022402; P:cell cycle process; IMP:MGI; .
GOGO:0009448; P:gamma-aminobutyric acid metabolic process; IMP:MGI; .
GOGO:0021782; P:glial cell development; IMP:MGI; .
GOGO:0006541; P:glutamine metabolic process; IMP:MGI; .
GOGO:0006544; P:glycine metabolic process; IMP:MGI; .
GOGO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW; .
GOGO:0021915; P:neural tube development; IMP:MGI; .
GOGO:0031175; P:neuron projection development; IMP:MGI; .
GOGO:0010468; P:regulation of gene expression; IMP:MGI; .
GOGO:0021510; P:spinal cord development; IMP:MGI; .
GOGO:0019530; P:taurine metabolic process; IMP:MGI; .
GOGO:0006566; P:threonine metabolic process; IMP:MGI; .
InterProIPR006236; D-3-Phosphoglycerate_DH; .
InterProIPR006139; D-isomer_2_OHA_DH_cat_dom; .
InterProIPR006140; D-isomer_2_OHA_DH_NAD-bd; .
InterProIPR016040; NAD(P)-bd_dom; .
Gene3DG3DSA:3.40.50.720; NAD(P)-bd; 2; .
PANTHERPTHR10996:SF20; D3PG_Deh; 1; .
PfamPF00389; 2-Hacid_dh; 1; .
PfamPF02826; 2-Hacid_dh_C; 1; .
TIGRFAMsTIGR01327; PGDH; 1; .
PROSITEPS00065; D_2_HYDROXYACID_DH_1; 1; .
PROSITEPS00670; D_2_HYDROXYACID_DH_2; 1; .
PROSITEPS00671; D_2_HYDROXYACID_DH_3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server