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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: TCPB_HUMAN



General information about the entry
View entry in simple text format
Entry nameTCPB_HUMAN
Primary accession numberP78371
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;.
Gene nameName=CCT2
Synonyms=99D8.1, CCTB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

pI=6.56; Mw=55522  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP78371; TCPB_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTCPB_HUMAN
Primary accession numberP78371
Secondary accession number(s) Q14D36 Q6IAT3
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on September 21, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;
Gene nameName=CCT2
Synonyms=99D8.1, CCTB
Encoded onName=CCT2; Synonyms=99D8.1, CCTB
KeywordsAcetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAF026293; AAC96012.1; -; mRNA
EMBLAF026166; AAC98906.1; -; mRNA
EMBLBT019966; AAV38769.1; -; mRNA
EMBLCR457071; CAG33352.1; -; mRNA
EMBLBC113514; AAI13515.1; -; mRNA
EMBLBC113516; AAI13517.1; -; mRNA
EMBLU91327; AAB67249.1; -; Genomic_DNA
IPIIPI00297779; -; .
RefSeqNP_006422.1; NM_006431.2; .
UniGeneHs.189772; -; .
ProteinModelPortalP78371; -; .
SMRP78371; 14-526; .
IntActP78371; 29; .
MINTMINT-1133770; -; .
STRINGP78371; -; .
PhosphoSiteP78371; -; .
SWISS-2DPAGEP78371; -; .
OGPP78371; -; .
UCD-2DPAGEP78371; -; .
PeptideAtlasP78371; -; .
PRIDEP78371; -; .
EnsemblENST00000299300; ENSP00000299300; ENSG00000166226; .
GeneID10576; -; .
KEGGhsa:10576; -; .
UCSCuc001svb.1; human; .
CTD10576; -; .
GeneCardsGC12P067028; -; .
H-InvDBHIX0036680; -; .
HGNCHGNC:1615; CCT2; .
HPACAB009850; -; .
HPAHPA003197; -; .
HPAHPA003198; -; .
MIM605139; gene; .
neXtProtNX_P78371; -; .
PharmGKBPA26179; -; .
eggNOGprNOG11386; -; .
HOGENOMHBG497503; -; .
HOVERGENHBG001052; -; .
InParanoidP78371; -; .
OrthoDBEOG47WNNK; -; .
PhylomeDBP78371; -; .
ReactomeREACT_17015; Metabolism of proteins; .
NextBio40141; -; .
ArrayExpressP78371; -; .
BgeeP78371; -; .
CleanExHS_CCT2; -; .
GenevestigatorP78371; -; .
GermOnlineENSG00000166226; Homo sapiens; .
GOGO:0005634; C:nucleus; IDA:HPA; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; NAS:UniProtKB; .
GOGO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome; .
InterProIPR012716; Chap_CCT_beta; .
InterProIPR017998; Chaperone_TCP-1; .
InterProIPR002194; Chaperonin_TCP-1_CS; .
InterProIPR002423; Cpn60/TCP-1; .
PANTHERPTHR11353:SF23; Chap_CCT_beta; 1; .
PANTHERPTHR11353; Cpn60/TCP-1; 1; .
PfamPF00118; Cpn60_TCP1; 1; .
SUPFAMSSF48592; GroEL-ATPase; 1; .
TIGRFAMsTIGR02341; Chap_CCT_beta; 1; .
PROSITEPS00750; TCP1_1; 1; .
PROSITEPS00751; TCP1_2; 1; .
PROSITEPS00995; TCP1_3; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server