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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: TCTP_HUMAN




SWISS-2DPAGE:  TCTP_HUMAN


TCTP_HUMAN


General information about the entry
View entry in simple text format
Entry nameTCTP_HUMAN
Primary accession numberP13693
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMay 15, 2003 (version 3)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Translationally-controlled tumor protein; Short=TCTP; AltName: Full=Fortilin; AltName: Full=Histamine-releasing factor; Short=HRF; AltName: Full=p23;.
Gene nameName=TPT1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J.
''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';''
Electrophoresis 13(1):992-1001(1992)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
[3]   MAPPING ON GEL
MEDLINE=94147970; PubMed=8313871; [NCBI, Expasy, EBI, Israel, Japan]
Golaz O., Hughes G.J., Frutiger S., Paquet N., Bairoch A., Pasquali C., Sanchez J.-C., Tissot J.-D., Appel R.D., Walzer C., Balant L.P., Hochstrasser D.F.
''''''Plasma and red blood cell protein maps: update 1993'';'';''
Electrophoresis 14(1):1223-1231(1993)
[4]   MAPPING ON GEL
MEDLINE=96007935; PubMed=7498158; [NCBI, Expasy, EBI, Israel, Japan]
Gravel P., Sanchez J.-C., Walzer C., Golaz O., Hochstrasser D.F., Balant L.P., Hughes G.J., Garcia-Sevilla J., Guimon J.
''''''Human blood platelet protein map established by two-dimensional polyacrylamide gel electrophoresis'';'';''
Electrophoresis 16(1):1152-1159(1995)
[5]   MAPPING ON GEL
MEDLINE=98163346; PubMed=9504818; [NCBI, Expasy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.
''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';''
Electrophoresis 18(1):2842-2848(1997)
[6]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

CEC_HUMAN {Colorectal epithelia cells}
Homo sapiens (Human)
Tissue: Colon epithelium
CEC_HUMAN
  map experimental info
  protein estimated location
 
CEC_HUMAN

MAP LOCATIONS:
pI=4.75; Mw=21091

MAPPING (identification):
IMMUNODETECTION [5].



DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=4.86; Mw=22200

MAPPING (identification):
GEL MATCHING WITH HEPG2 MASTER AND IMMUNOBLOTTING [6].



ELC_HUMAN {Erythroleukemia Cell}
Homo sapiens (Human)
Tissue: Erythroleukemia
ELC_HUMAN
  map experimental info
  protein estimated location
 
ELC_HUMAN

MAP LOCATIONS:
pI=4.72; Mw=22134

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



HEPG2_HUMAN {HepG2}
Homo sapiens (Human)
Tissue: Hepatoblastoma
HEPG2_HUMAN
  map experimental info
  protein estimated location
 
HEPG2_HUMAN

MAP LOCATIONS:
pI=4.86; Mw=22200

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



LIVER_HUMAN {Liver}
Homo sapiens (Human)
Tissue: Liver
LIVER_HUMAN
  map experimental info
  protein estimated location
 
LIVER_HUMAN

MAP LOCATIONS:
pI=4.86; Mw=22045

MAPPING (identification):
MICROSEQUENCING [1].



LYMPHOMA_HUMAN {Lymphoma}
Homo sapiens (Human)
Tissue: Lymphoma
LYMPHOMA_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOMA_HUMAN

MAP LOCATIONS:
pI=4.75; Mw=21895
pI=4.81; Mw=21724

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].



PLATELET_HUMAN {Platelet}
Homo sapiens (Human)
Tissue: Platelet
PLATELET_HUMAN
  map experimental info
  protein estimated location
 
PLATELET_HUMAN

MAP LOCATIONS:
pI=4.84; Mw=21800

MAPPING (identification):
MATCHING WITH RBC AND LIVER MASTERS [4].



RBC_HUMAN {Red blood cells}
Homo sapiens (Human)
Tissue: Erythrocyte
RBC_HUMAN
  map experimental info
  protein estimated location
 
RBC_HUMAN

MAP LOCATIONS:
pI=4.85; Mw=21148

MAPPING (identification):
MICROSEQUENCING [3].



U937_HUMAN {Macrophage Like Cell Line}
Homo sapiens (Human)
Tissue: Histiocytic lymphoma
U937_HUMAN
  map experimental info
  protein estimated location
 
U937_HUMAN

MAP LOCATIONS:
pI=4.87; Mw=21874

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP13693; P13693.
DOSAC-COBS-2DPAGEP13693; TCTP_HUMAN.
OGP-WWWP13693.
REPRODUCTION-2DPAGEIPI00550900; IPI00550900.
Siena-2DPAGEP13693; TCTP_HUMAN.
UniProtKB/Swiss-ProtP13693; TCTP_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTCTP_HUMAN
Primary accession numberP13693
Secondary accession number(s) B2R7E5 Q6YLS2 Q7Z4J4 Q96EE2 Q9UC70
Sequence was last modified on January 1, 1990 (version 1)
Annotations were last modified on October 19, 2011 (version 130)
Name and origin of the protein
DescriptionRecName: Full=Translationally-controlled tumor protein; Short=TCTP; AltName: Full=Fortilin; AltName: Full=Histamine-releasing factor; Short=HRF; AltName: Full=p23;
Gene nameName=TPT1
Encoded onName=TPT1
Keywords3D-structure; Acetylation; Calcium; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX16064; CAA34200.1; -; mRNA
EMBLAJ400717; CAB87812.1; -; Genomic_DNA
EMBLAY334563; AAQ01550.1; -; mRNA
EMBLAY117678; AAM51565.1; -; mRNA
EMBLCR457036; CAG33317.1; -; mRNA
EMBLAK312951; BAG35792.1; -; mRNA
EMBLAL138963; CAH72034.1; -; Genomic_DNA
EMBLCH471075; EAX08732.1; -; Genomic_DNA
EMBLBC003352; AAH03352.1; -; mRNA
EMBLBC012431; AAH12431.1; -; mRNA
EMBLBC052333; AAH52333.1; -; mRNA
IPIIPI00550900; -; .
PIRS06590; S06590; .
RefSeqNP_003286.1; NM_003295.2; .
UniGeneHs.374596; -; .
PDB1YZ1; X-ray; 2.00 A; A/B/C/D=1-172
PDB2HR9; NMR; -; A=1-172
PDB3EBM; X-ray; 2.60 A; A/B/C/D=1-172
PDBsum1YZ1; -; .
PDBsum2HR9; -; .
PDBsum3EBM; -; .
ProteinModelPortalP13693; -; .
SMRP13693; 1-172; .
IntActP13693; 23; .
MINTMINT-2634453; -; .
STRINGP13693; -; .
Allergome3816; Hom s TCTP; .
PhosphoSiteP13693; -; .
SWISS-2DPAGEP13693; -; .
Aarhus/Ghent-2DPAGE8114; IEF; .
Aarhus/Ghent-2DPAGE9119; IEF; .
DOSAC-COBS-2DPAGEP13693; -; .
OGPP13693; -; .
REPRODUCTION-2DPAGEIPI00550900; -; .
Siena-2DPAGEP13693; -; .
PRIDEP13693; -; .
EnsemblENST00000309246; ENSP00000339051; ENSG00000133112; .
EnsemblENST00000379060; ENSP00000368350; ENSG00000133112; .
GeneID7178; -; .
KEGGhsa:7178; -; .
UCSCuc001uzy.1; human; .
CTD7178; -; .
GeneCardsGC13M026712; -; .
H-InvDBHIX0011286; -; .
H-InvDBHIX0028410; -; .
H-InvDBHIX0034276; -; .
HGNCHGNC:12022; TPT1; .
HPACAB008364; -; .
MIM600763; gene; .
neXtProtNX_P13693; -; .
PharmGKBPA36701; -; .
eggNOGprNOG17188; -; .
HOVERGENHBG002282; -; .
InParanoidP13693; -; .
OrthoDBEOG4FJ89Z; -; .
PhylomeDBP13693; -; .
NextBio28136; -; .
ArrayExpressP13693; -; .
BgeeP13693; -; .
CleanExHS_TPT1; -; .
GenevestigatorP13693; -; .
GermOnlineENSG00000133112; Homo sapiens; .
GOGO:0005615; C:extracellular space; IDA:MGI; .
GOGO:0005771; C:multivesicular body; IDA:MGI; .
GOGO:0005509; F:calcium ion binding; IDA:UniProtKB; .
GOGO:0006916; P:anti-apoptosis; TAS:UniProtKB; .
GOGO:0006816; P:calcium ion transport; IC:UniProtKB; .
GOGO:0006874; P:cellular calcium ion homeostasis; IC:UniProtKB; .
GOGO:0009615; P:response to virus; IEP:UniProtKB; .
InterProIPR011057; Mss4-like; .
InterProIPR011323; Mss4/transl-control_tumor; .
InterProIPR018103; Translation_control_tumour_CS; .
InterProIPR018105; Translational_control_tumour_p; .
Gene3DG3DSA:2.170.150.10; Mss4/transl-control_tumor; 1; .
PANTHERPTHR11991; TCTP; 1; .
PfamPF00838; TCTP; 1; .
PRINTSPR01653; TCTPROTEIN; .
SUPFAMSSF51316; Mss4_like; 1; .
PROSITEPS01002; TCTP_1; 1; .
PROSITEPS01003; TCTP_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server