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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P02790




SWISS-2DPAGE:  P02790


P02790


General information about the entry
View entry in simple text format
Entry nameHEMO_HUMAN
Primary accession numberP02790
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 1, 2000 (version 1)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Hemopexin; AltName: Full=Beta-1B-glycoprotein; Flags: Precursor;.
Gene nameName=HPX
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=78094420; PubMed=271964; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Anderson N.G.
''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';''
Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
Comments
  • SUBUNIT: SINGLE CHAIN
2D PAGE maps for identified proteins
How to interpret a protein

CSF_HUMAN {Cerebrospinal Fluid}
Homo sapiens (Human)
Tissue: Cerebrospinal fluid
CSF_HUMAN
  map experimental info
  protein estimated location
 
CSF_HUMAN

MAP LOCATIONS:
pI=5.34; Mw=77746
pI=5.43; Mw=76342
pI=5.51; Mw=74964
pI=5.58; Mw=73076
pI=5.67; Mw=71495

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [2].



HEPG2SP_HUMAN {HepG2 Secreted Proteins}
Homo sapiens (Human)
Tissue: Hepatoblastoma
HEPG2SP_HUMAN
  map experimental info
  protein estimated location
 
HEPG2SP_HUMAN

MAP LOCATIONS:
pI=5.37; Mw=71095
pI=5.34; Mw=71625
pI=5.31; Mw=71360
pI=5.41; Mw=70832
pI=5.45; Mw=70309
pI=5.49; Mw=67000
pI=5.41; Mw=66781
pI=5.45; Mw=66563

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [2].



PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=5.25; Mw=77155
pI=5.33; Mw=76277
pI=5.43; Mw=74551
pI=5.53; Mw=73703
pI=5.59; Mw=72036
pI=4.48; Mw=19274
pI=4.56; Mw=18289

NORMAL LEVEL:
500-1150 MG/L.

PATHOLOGICAL LEVEL:
DECREASED DURING HAEMOLYTIC ANAEMIAS.

MAPPING (identification):
IMMUNOBLOTTING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP02790; P02790.
DOSAC-COBS-2DPAGEP02790; HEMO_HUMAN.
REPRODUCTION-2DPAGEIPI00022488; IPI00022488.
Siena-2DPAGEP02790; HEMO_HUMAN.
UniProtKB/Swiss-ProtP02790; HEMO_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameHEMO_HUMAN
Primary accession numberP02790
Secondary accession number(s) B2R957
Sequence was last modified on October 1, 1996 (version 2)
Annotations were last modified on September 21, 2011 (version 120)
Name and origin of the protein
DescriptionRecName: Full=Hemopexin; AltName: Full=Beta-1B-glycoprotein; Flags: Precursor;
Gene nameName=HPX
Encoded onName=HPX
KeywordsComplete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Heme; Host-virus interaction; Iron; Metal-binding; Polymorphism; Reference proteome; Repeat; Secreted; Signal; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM36803; AAA58678.1; -; Genomic_DNA
EMBLM36796; AAA58678.1; JOINED; Genomic_DNA
EMBLM36799; AAA58678.1; JOINED; Genomic_DNA
EMBLM36800; AAA58678.1; JOINED; Genomic_DNA
EMBLM36801; AAA58678.1; JOINED; Genomic_DNA
EMBLM36802; AAA58678.1; JOINED; Genomic_DNA
EMBLAK313648; BAG36404.1; -; mRNA
EMBLJ03048; AAA52704.1; -; mRNA
EMBLX02537; CAA26382.1; ALT_INIT; mRNA
IPIIPI00022488; -; .
PIRI56456; OQHU; .
RefSeqNP_000604.1; NM_000613.2; .
UniGeneHs.426485; -; .
ProteinModelPortalP02790; -; .
SMRP02790; 48-462; .
IntActP02790; 1; .
STRINGP02790; -; .
PhosphoSiteP02790; -; .
SWISS-2DPAGEP02790; -; .
Cornea-2DPAGEP02790; -; .
DOSAC-COBS-2DPAGEP02790; -; .
REPRODUCTION-2DPAGEIPI00022488; -; .
Siena-2DPAGEP02790; -; .
PeptideAtlasP02790; -; .
PRIDEP02790; -; .
EnsemblENST00000265983; ENSP00000265983; ENSG00000110169; .
GeneID3263; -; .
KEGGhsa:3263; -; .
UCSCuc001mdg.1; human; .
CTD3263; -; .
GeneCardsGC11M006112; -; .
H-InvDBHIX0009399; -; .
HGNCHGNC:5171; HPX; .
HPACAB016725; -; .
MIM142290; gene; .
neXtProtNX_P02790; -; .
PharmGKBPA29441; -; .
eggNOGprNOG07404; -; .
HOGENOMHBG445745; -; .
HOVERGENHBG005956; -; .
InParanoidP02790; -; .
OMACHRGECQ; -; .
OrthoDBEOG4R502N; -; .
PhylomeDBP02790; -; .
NextBio12957; -; .
ArrayExpressP02790; -; .
BgeeP02790; -; .
CleanExHS_HPX; -; .
GenevestigatorP02790; -; .
GermOnlineENSG00000110169; Homo sapiens; .
GOGO:0005615; C:extracellular space; TAS:ProtInc; .
GOGO:0015232; F:heme transporter activity; TAS:ProtInc; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0006879; P:cellular iron ion homeostasis; TAS:ProtInc; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
InterProIPR000585; Hemopexin/matrixin; .
InterProIPR018486; Hemopexin/matrixin_CS; .
InterProIPR018487; Hemopexin/matrixin_repeat; .
InterProIPR016358; Hemopexin_chordata; .
Gene3DG3DSA:2.110.10.10; Hemopexin; 2; .
PfamPF00045; Hemopexin; 5; .
PIRSFPIRSF002551; Hemopexin_chordata; 1; .
SMARTSM00120; HX; 5; .
SUPFAMSSF50923; Hemopexin; 2; .
PROSITEPS00024; HEMOPEXIN; 2; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server