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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P04117




SWISS-2DPAGE:  P04117


P04117


General information about the entry
View entry in simple text format
Entry nameFABP4_MOUSE
Primary accession numberP04117
integrated into SWISS-2DPAGE on April 1, 2000 (release 12)
2D Annotations were last modified onMay 15, 2003 (version 3)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Fatty acid-binding protein, adipocyte; AltName: Full=3T3-L1 lipid-binding protein; AltName: Full=Adipocyte lipid-binding protein; Short=ALBP; AltName: Full=Adipocyte-type fatty acid-binding protein; Short=A-FABP; Short=AFABP; AltName: Full=Fatty acid-binding protein 4; AltName: Full=Myelin P2 protein homolog; AltName: Full=P15; AltName: Full=P2 adipocyte protein; AltName: Full=Protein 422;.
Gene nameName=Fabp4
Synonyms=Ap2
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
[2]   MAPPING ON GEL
PubMed=11503206; [NCBI, ExPASy, EBI, Israel, Japan]
Lanne B., Potthast F., Hoglund A., Brockenhuus Von Lowenhielm H., Nystrom A.-C., Nilsson F., Dahllof B.
''''''Thiourea enhances mapping of the proteome from murine white adipose tissue'';'';''
Proteomics 1(1):819-828(2001)
[3]   MAPPING ON GEL
Tonella L., Hoogland C., Sanchez J.-C.
Submitted (OCT-2001) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=9.22; Mw=12860
pI=8.66; Mw=12742
pI=8.96; Mw=12801
pI=8.38; Mw=12742

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=8.32; Mw=10828  [identification data]
pI=8.63; Mw=10956  [identification data]
pI=6.83; Mw=10062

MAPPING (identification):
SPOTS 2D-001CI*: Peptide mass fingerprinting [1];
SPOT 2D-001CKF: GEL MATCHING [3] WITH WAT_MOUSE 2-DE MAP FROM LANNE ET AL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from license@isb-sib.ch).
Cross-references
UniProtKB/Swiss-ProtP04117; FABP4_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameFABP4_MOUSE
Primary accession numberP04117
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 129)
Name and origin of the protein
DescriptionRecName: Full=Fatty acid-binding protein, adipocyte; AltName: Full=3T3-L1 lipid-binding protein; AltName: Full=Adipocyte lipid-binding protein; Short=ALBP; AltName: Full=Adipocyte-type fatty acid-binding protein; Short=A-FABP; Short=AFABP; AltName: Full=Fatty acid-binding protein 4; AltName: Full=Myelin P2 protein homolog; AltName: Full=P15; AltName: Full=P2 adipocyte protein; AltName: Full=Protein 422;
Gene nameName=Fabp4
Synonyms=Ap2
Encoded onName=Fabp4; Synonyms=Ap2
Keywords3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Lipid-binding; Nucleus; Phosphoprotein; Reference proteome; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLK02109; AAA39416.1; -; mRNA
EMBLM13264; AAA39870.1; -; Genomic_DNA
EMBLM13261; AAA39870.1; JOINED; Genomic_DNA
EMBLM13262; AAA39870.1; JOINED; Genomic_DNA
EMBLM13263; AAA39870.1; JOINED; Genomic_DNA
EMBLM13385; AAA39417.1; -; Genomic_DNA
EMBLAK003143; BAB22601.1; -; mRNA
EMBLBC054426; AAH54426.1; -; mRNA
EMBLM20497; AAA37188.1; -; Genomic_DNA
EMBLM28726; AAA37112.1; -; mRNA
IPIIPI00116705; -; .
PIRB25952; B25952; .
RefSeqNP_077717.1; NM_024406.2; .
UniGeneMm.582; -; .
PDB1A18; X-ray; 2.40 A; A=2-131
PDB1A2D; X-ray; 2.40 A; A/B=2-131
PDB1AB0; X-ray; 1.90 A; A=3-131
PDB1ACD; X-ray; 2.70 A; A=3-131
PDB1ADL; X-ray; 1.60 A; A=2-132
PDB1ALB; X-ray; 2.50 A; A=2-132
PDB1G74; X-ray; 1.70 A; A=2-132
PDB1G7N; X-ray; 1.50 A; A=2-132
PDB1LIB; X-ray; 1.70 A; A=2-132
PDB1LIC; X-ray; 1.60 A; A=2-132
PDB1LID; X-ray; 1.60 A; A=2-132
PDB1LIE; X-ray; 1.60 A; A=2-132
PDB1LIF; X-ray; 1.60 A; A=2-132
PDB2ANS; X-ray; 2.50 A; A/B=2-132
PDB2Q9S; X-ray; 2.30 A; A=1-132
PDB2QM9; X-ray; 2.31 A; A/B=1-132
PDB3HK1; X-ray; 1.70 A; A=2-132
PDB3JS1; X-ray; 1.81 A; A/B=2-132
PDB3JSQ; X-ray; 2.30 A; A=2-132
PDBsum1A18; -; .
PDBsum1A2D; -; .
PDBsum1AB0; -; .
PDBsum1ACD; -; .
PDBsum1ADL; -; .
PDBsum1ALB; -; .
PDBsum1G74; -; .
PDBsum1G7N; -; .
PDBsum1LIB; -; .
PDBsum1LIC; -; .
PDBsum1LID; -; .
PDBsum1LIE; -; .
PDBsum1LIF; -; .
PDBsum2ANS; -; .
PDBsum2Q9S; -; .
PDBsum2QM9; -; .
PDBsum3HK1; -; .
PDBsum3JS1; -; .
PDBsum3JSQ; -; .
ProteinModelPortalP04117; -; .
SMRP04117; 2-132; .
STRINGP04117; -; .
PhosphoSiteP04117; -; .
SWISS-2DPAGEP04117; -; .
PRIDEP04117; -; .
EnsemblENSMUST00000029041; ENSMUSP00000029041; ENSMUSG00000062515; .
GeneID11770; -; .
KEGGmmu:11770; -; .
CTD2167; -; .
MGIMGI:88038; Fabp4; .
HOGENOMHBG714759; -; .
HOVERGENHBG005633; -; .
InParanoidP04117; -; .
OMAGQEFDEI; -; .
OrthoDBEOG4QC16R; -; .
PhylomeDBP04117; -; .
NextBio279545; -; .
ArrayExpressP04117; -; .
BgeeP04117; -; .
CleanExMM_FABP4; -; .
GenevestigatorP04117; -; .
GermOnlineENSMUSG00000062515; Mus musculus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0008289; F:lipid binding; IEA:UniProtKB-KW; .
GOGO:0005215; F:transporter activity; IEA:InterPro; .
GOGO:0050873; P:brown fat cell differentiation; IDA:MGI; .
GOGO:0071285; P:cellular response to lithium ion; IDA:MGI; .
GOGO:0042632; P:cholesterol homeostasis; IMP:MGI; .
GOGO:0001816; P:cytokine production; IMP:MGI; .
GOGO:0006469; P:negative regulation of protein kinase activity; IMP:MGI; .
GOGO:0045892; P:negative regulation of transcription; DNA-dependent; IMP:MGI
GOGO:0050729; P:positive regulation of inflammatory response; IMP:MGI; .
GOGO:0050872; P:white fat cell differentiation; IDA:MGI; .
InterProIPR012674; Calycin; .
InterProIPR011038; Calycin-like; .
InterProIPR000463; Fatty_acid-bd; .
InterProIPR000566; Lipocln_cytosolic_FA-bd_dom; .
Gene3DG3DSA:2.40.128.20; Calycin; 1; .
PfamPF00061; Lipocalin; 1; .
PRINTSPR00178; FATTYACIDBP; .
SUPFAMSSF50814; Calycin; 1; .
PROSITEPS00214; FABP; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server