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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P05109




SWISS-2DPAGE:  P05109


P05109


General information about the entry
View entry in simple text format
Entry nameS10A8_HUMAN
Primary accession numberP05109
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Protein S100-A8; AltName: Full=Calgranulin-A; AltName: Full=Calprotectin L1L subunit; AltName: Full=Cystic fibrosis antigen; Short=CFAG; AltName: Full=Leukocyte L1 complex light chain; AltName: Full=Migration inhibitory factor-related protein 8; Short=MRP-8; Short=p8; AltName: Full=S100 calcium-binding protein A8; AltName: Full=Urinary stone protein band A;.
Gene nameName=S100A8
Synonyms=CAGA, CFAG, MRP8
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
Comments
  • SUBUNIT: Homodimer
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=73806  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
PMMA-2DPAGEP05109.
Siena-2DPAGEP05109; S10A8_HUMAN.
UniProtKB/Swiss-ProtP05109; S10A8_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameS10A8_HUMAN
Primary accession numberP05109
Secondary accession number(s) A8K5L3 D3DV37 Q5SY70 Q9UC84 Q9UC92 Q9UCJ0 Q9UCM6
Sequence was last modified on January 1, 1988 (version 1)
Annotations were last modified on October 19, 2011 (version 130)
Name and origin of the protein
DescriptionRecName: Full=Protein S100-A8; AltName: Full=Calgranulin-A; AltName: Full=Calprotectin L1L subunit; AltName: Full=Cystic fibrosis antigen; Short=CFAG; AltName: Full=Leukocyte L1 complex light chain; AltName: Full=Migration inhibitory factor-related protein 8; Short=MRP-8; Short=p8; AltName: Full=S100 calcium-binding protein A8; AltName: Full=Urinary stone protein band A;
Gene nameName=S100A8
Synonyms=CAGA, CFAG, MRP8
Encoded onName=S100A8; Synonyms=CAGA, CFAG, MRP8
Keywords3D-structure; Antimicrobial; Calcium; Cell membrane; Chemotaxis; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Reference proteome; Repeat; Secreted.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLY00278; CAA68390.1; -; mRNA
EMBLX06234; CAA29580.1; -; mRNA
EMBLM21005; AAA36327.1; -; Genomic_DNA
EMBLAK291328; BAF84017.1; -; mRNA
EMBLCR407674; CAG28602.1; -; mRNA
EMBLBT007378; AAP36042.1; -; mRNA
EMBLAL591704; CAI19497.1; -; Genomic_DNA
EMBLCH471121; EAW53330.1; -; Genomic_DNA
EMBLCH471121; EAW53331.1; -; Genomic_DNA
EMBLBC005928; AAH05928.1; -; mRNA
IPIIPI00007047; -; .
PIRA31848; BCHUCF; .
RefSeqNP_002955.2; NM_002964.4; .
UniGeneHs.416073; -; .
PDB1MR8; X-ray; 1.90 A; A/B=1-93
PDB1XK4; X-ray; 1.80 A; A/B/E/F/I/J=1-93
PDBsum1MR8; -; .
PDBsum1XK4; -; .
ProteinModelPortalP05109; -; .
SMRP05109; 1-90; .
DIPDIP-1165N; -; .
IntActP05109; 24; .
MINTMINT-1151603; -; .
STRINGP05109; -; .
SWISS-2DPAGEP05109; -; .
Aarhus/Ghent-2DPAGE1003; IEF; .
PMMA-2DPAGEP05109; -; .
PeptideAtlasP05109; -; .
PRIDEP05109; -; .
EnsemblENST00000368732; ENSP00000357721; ENSG00000143546; .
EnsemblENST00000368733; ENSP00000357722; ENSG00000143546; .
GeneID6279; -; .
KEGGhsa:6279; -; .
UCSCuc001fbs.1; human; .
CTD6279; -; .
GeneCardsGC01M124725; -; .
H-InvDBHIX0001079; -; .
HGNCHGNC:10498; S100A8; .
HPACAB002791; -; .
HPAHPA024372; -; .
MIM123885; gene; .
neXtProtNX_P05109; -; .
PharmGKBPA34910; -; .
eggNOGprNOG21380; -; .
GeneTreeENSGT00590000083207; -; .
HOVERGENHBG001479; -; .
InParanoidP05109; -; .
OMAKDADTWF; -; .
OrthoDBEOG4V9TS7; -; .
PhylomeDBP05109; -; .
NextBio24373; -; .
ArrayExpressP05109; -; .
BgeeP05109; -; .
CleanExHS_S100A8; -; .
GenevestigatorP05109; -; .
GermOnlineENSG00000143546; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0005509; F:calcium ion binding; TAS:ProtInc; .
GOGO:0005515; F:protein binding; IPI:IntAct; .
GOGO:0006935; P:chemotaxis; IEA:UniProtKB-KW; .
InterProIPR011992; EF-hand-like_dom; .
InterProIPR018247; EF_Hand_1_Ca_BS; .
InterProIPR018249; EF_HAND_2; .
InterProIPR001751; S100/CaBP-9k_CS; .
InterProIPR013787; S100_Ca-bd_sub; .
Gene3DG3DSA:1.10.238.10; EF-Hand_type; 1; .
PfamPF01023; S_100; 1; .
PROSITEPS00018; EF_HAND_1; 1; .
PROSITEPS50222; EF_HAND_2; 1; .
PROSITEPS00303; S100_CABP; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server