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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P08228




SWISS-2DPAGE:  P08228


P08228


General information about the entry
View entry in simple text format
Entry nameSODC_MOUSE
Primary accession numberP08228
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Superoxide dismutase [Cu-Zn]; EC=1.15.1.1;.
Gene nameName=Sod1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=6.15; Mw=14537

MAPPING (identification):
MATCHING [2] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=6.10; Mw=14326

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [2].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=6.07; Mw=12726

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP08228; P08228.
DOSAC-COBS-2DPAGEP08228; SODC_MOUSE.
REPRODUCTION-2DPAGEP08228; P08228.
REPRODUCTION-2DPAGEIPI00130589; IPI00130589.
UCD-2DPAGEP08228; SODC_MOUSE.
UniProtKB/Swiss-ProtP08228; SODC_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameSODC_MOUSE
Primary accession numberP08228
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on September 21, 2011 (version 137)
Name and origin of the protein
DescriptionRecName: Full=Superoxide dismutase [Cu-Zn]; EC=1.15.1.1;
Gene nameName=Sod1
Encoded onName=Sod1
Keywords3D-structure; Acetylation; Antioxidant; Complete proteome; Copper; Cytoplasm; Direct protein sequencing; Disulfide bond; Metal-binding; Oxidoreductase; Phosphoprotein; Reference proteome; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX06683; CAA29880.1; -; mRNA
EMBLM60798; AAA40121.1; -; Genomic_DNA
EMBLM60794; AAA40121.1; JOINED; Genomic_DNA
EMBLM60795; AAA40121.1; JOINED; Genomic_DNA
EMBLM60796; AAA40121.1; JOINED; Genomic_DNA
EMBLM60797; AAA40121.1; JOINED; Genomic_DNA
EMBLM35725; AAA37518.1; -; mRNA
EMBLAK020624; BAB32154.1; -; mRNA
EMBLAK077284; BAC36730.1; -; mRNA
EMBLBC002066; AAH02066.1; -; mRNA
EMBLBC048874; AAH48874.1; -; mRNA
EMBLBC086886; AAH86886.1; -; mRNA
IPIIPI00130589; -; .
PIRJQ0915; JQ0915; .
RefSeqNP_035564.1; NM_011434.1; .
UniGeneMm.276325; -; .
UniGeneMm.466779; -; .
PDB3GTT; X-ray; 2.40 A; A/B/C/D/E/F=2-154
PDB3GTV; X-ray; 2.20 A; A/B/C/D/E/F/G/H/I/J/K/L=82-154
PDBsum3GTT; -; .
PDBsum3GTV; -; .
ProteinModelPortalP08228; -; .
SMRP08228; 2-154; .
DIPDIP-48691N; -; .
IntActP08228; 2; .
STRINGP08228; -; .
PhosphoSiteP08228; -; .
SWISS-2DPAGEP08228; -; .
DOSAC-COBS-2DPAGEP08228; -; .
REPRODUCTION-2DPAGEIPI00130589; -; .
REPRODUCTION-2DPAGEP08228; -; .
UCD-2DPAGEP08228; -; .
PRIDEP08228; -; .
EnsemblENSMUST00000023707; ENSMUSP00000023707; ENSMUSG00000022982; .
GeneID20655; -; .
KEGGmmu:20655; -; .
NMPDRfig|10090.3.peg.1866; -; .
UCSCuc007zvz.1; mouse; .
CTD6647; -; .
MGIMGI:98351; Sod1; .
eggNOGroNOG15892; -; .
GeneTreeENSGT00530000063226; -; .
HOGENOMHBG609879; -; .
HOVERGENHBG000062; -; .
InParanoidP08228; -; .
OMAIHFEQKA; -; .
OrthoDBEOG45HRZM; -; .
PhylomeDBP08228; -; .
NextBio299081; -; .
ArrayExpressP08228; -; .
BgeeP08228; -; .
CleanExMM_SOD1; -; .
GenevestigatorP08228; -; .
GermOnlineENSMUSG00000047905; Mus musculus; .
GOGO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB; .
GOGO:0005829; C:cytosol; ISS:UniProtKB; .
GOGO:0032839; C:dendrite cytoplasm; ISS:UniProtKB; .
GOGO:0031012; C:extracellular matrix; ISS:UniProtKB; .
GOGO:0005615; C:extracellular space; ISS:UniProtKB; .
GOGO:0005739; C:mitochondrion; ISS:UniProtKB; .
GOGO:0043025; C:neuronal cell body; ISS:UniProtKB; .
GOGO:0005634; C:nucleus; ISS:UniProtKB; .
GOGO:0043234; C:protein complex; ISS:UniProtKB; .
GOGO:0051087; F:chaperone binding; ISS:UniProtKB; .
GOGO:0005507; F:copper ion binding; ISS:UniProtKB; .
GOGO:0030346; F:protein phosphatase 2B binding; ISS:UniProtKB; .
GOGO:0004784; F:superoxide dismutase activity; IDA:MGI; .
GOGO:0008270; F:zinc ion binding; ISS:UniProtKB; .
GOGO:0000187; P:activation of MAPK activity; IDA:MGI; .
GOGO:0060088; P:auditory receptor cell stereocilium organization; IMP:MGI; .
GOGO:0007569; P:cell aging; ISS:UniProtKB; .
GOGO:0006879; P:cellular iron ion homeostasis; IMP:MGI; .
GOGO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IDA:MGI; .
GOGO:0006302; P:double-strand break repair; IMP:MGI; .
GOGO:0007566; P:embryo implantation; IMP:MGI; .
GOGO:0006749; P:glutathione metabolic process; IMP:MGI; .
GOGO:0060047; P:heart contraction; IMP:MGI; .
GOGO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI; .
GOGO:0007626; P:locomotory behavior; IMP:MGI; .
GOGO:0046716; P:muscle cell homeostasis; IMP:MGI; .
GOGO:0002262; P:myeloid cell homeostasis; IMP:MGI; .
GOGO:0045541; P:negative regulation of cholesterol biosynthetic process; ISS:UniProtKB; .
GOGO:0043524; P:negative regulation of neuron apoptosis; IMP:MGI; .
GOGO:0060052; P:neurofilament cytoskeleton organization; IMP:MGI; .
GOGO:0001541; P:ovarian follicle development; IMP:MGI; .
GOGO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI; .
GOGO:0001819; P:positive regulation of cytokine production; ISS:UniProtKB; .
GOGO:0008217; P:regulation of blood pressure; IMP:MGI; .
GOGO:0051881; P:regulation of mitochondrial membrane potential; ISS:UniProtKB; .
GOGO:0040014; P:regulation of multicellular organism growth; IMP:MGI; .
GOGO:0060087; P:relaxation of vascular smooth muscle; IMP:MGI; .
GOGO:0019430; P:removal of superoxide radicals; IMP:MGI; .
GOGO:0048678; P:response to axon injury; IMP:MGI; .
GOGO:0042493; P:response to drug; IMP:MGI; .
GOGO:0045471; P:response to ethanol; IMP:MGI; .
GOGO:0009408; P:response to heat; IMP:MGI; .
GOGO:0042542; P:response to hydrogen peroxide; IMP:MGI; .
GOGO:0001895; P:retina homeostasis; IMP:MGI; .
GOGO:0007605; P:sensory perception of sound; IMP:MGI; .
GOGO:0007283; P:spermatogenesis; IMP:MGI; .
GOGO:0042554; P:superoxide anion generation; IDA:MGI; .
InterProIPR024134; SOD_Cu/Zn_/chaperones; .
InterProIPR018152; SOD_Cu/Zn_BS; .
InterProIPR001424; SOD_Cu_Zn_dom; .
Gene3DG3DSA:2.60.40.200; SOD_Cu_Zn; 1; .
PANTHERPTHR10003; SOD_Cu_Zn; 1; .
PfamPF00080; Sod_Cu; 1; .
PRINTSPR00068; CUZNDISMTASE; .
SUPFAMSSF49329; SOD_Cu_Zn; 1; .
PROSITEPS00087; SOD_CU_ZN_1; 1; .
PROSITEPS00332; SOD_CU_ZN_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server