resource logo

SWISS-2DPAGE

Attention: World-2DPAGE is no longer maintained.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P10639




SWISS-2DPAGE:  P10639


P10639


General information about the entry
View entry in simple text format
Entry nameTHIO_MOUSE
Primary accession numberP10639
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 14)
Name and origin of the protein
DescriptionRecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF;.
Gene nameName=Txn
Synonyms=Txn1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=4.93; Mw=11945

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=4.91; Mw=12433  [identification data]

MAPPING (identification):
MICROSEQUENCING [1], AND MASS FINGERPRINTING [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=4.95; Mw=10362

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UCD-2DPAGEP10639; THIO_MOUSE.
UniProtKB/Swiss-ProtP10639; THIO_MOUSE.
World-2DPAGE RepositoryP10639; THIO_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTHIO_MOUSE
Primary accession numberP10639
Secondary accession number(s) Q52KC4 Q9D8R0
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on September 21, 2011 (version 112)
Name and origin of the protein
DescriptionRecName: Full=Thioredoxin; Short=Trx; AltName: Full=ATL-derived factor; Short=ADF;
Gene nameName=Txn
Synonyms=Txn1
Encoded onName=Txn; Synonyms=Txn1
KeywordsAcetylation; Activator; Complete proteome; Cytoplasm; Disulfide bond; Electron transport; Nucleus; Redox-active center; Reference proteome; S-nitrosylation; Secreted; Transcription; Transcription regulation; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX77585; CAA54688.1; -; mRNA
EMBLD21859; BAA04881.1; -; Genomic_DNA
EMBLAK007537; BAB25096.1; -; mRNA
EMBLAK007790; BAB25256.1; -; mRNA
EMBLBC010756; AAH10756.1; -; mRNA
EMBLBC094415; AAH94415.1; -; mRNA
IPIIPI00226993; -; .
PIRJC4068; S04107; .
RefSeqNP_035790.1; NM_011660.3; .
UniGeneMm.260618; -; .
ProteinModelPortalP10639; -; .
SMRP10639; 1-103; .
IntActP10639; 1; .
STRINGP10639; -; .
PhosphoSiteP10639; -; .
SWISS-2DPAGEP10639; -; .
UCD-2DPAGEP10639; -; .
PRIDEP10639; -; .
EnsemblENSMUST00000030051; ENSMUSP00000030051; ENSMUSG00000028367; .
GeneID22166; -; .
KEGGmmu:22166; -; .
CTD22166; -; .
MGIMGI:98874; Txn1; .
GeneTreeENSGT00530000063008; -; .
HOGENOMHBG493509; -; .
HOVERGENHBG009243; -; .
InParanoidP10639; -; .
OMAITTKESW; -; .
OrthoDBEOG47PX7J; -; .
PhylomeDBP10639; -; .
NextBio302106; -; .
ArrayExpressP10639; -; .
BgeeP10639; -; .
CleanExMM_TXN1; -; .
GenevestigatorP10639; -; .
GermOnlineENSMUSG00000028367; Mus musculus; .
GOGO:0005829; C:cytosol; IDA:MGI; .
GOGO:0005576; C:extracellular region; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0005634; C:nucleus; IDA:MGI; .
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0015037; F:peptide disulfide oxidoreductase activity; IDA:MGI; .
GOGO:0005515; F:protein binding; IPI:MGI; .
GOGO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; .
GOGO:0045454; P:cell redox homeostasis; IDA:MGI; .
GOGO:0022900; P:electron transport chain; IEA:UniProtKB-KW; .
GOGO:0006662; P:glycerol ether metabolic process; IEA:InterPro; .
GOGO:0046826; P:negative regulation of protein export from nucleus; IDA:MGI; .
GOGO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB; .
GOGO:0033158; P:regulation of protein import into nucleus; translocation; ISS:UniProtKB
GOGO:0006355; P:regulation of transcription; DNA-dependent; IEA:UniProtKB-KW
GOGO:0009314; P:response to radiation; ISS:UniProtKB; .
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
InterProIPR005746; Thioredoxin; .
InterProIPR012336; Thioredoxin-like_fold; .
InterProIPR017937; Thioredoxin_CS; .
InterProIPR013766; Thioredoxin_domain; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PANTHERPTHR10438; Trx; 1; .
PfamPF00085; Thioredoxin; 1; .
PIRSFPIRSF000077; Thioredoxin; 1; .
PRINTSPR00421; THIOREDOXIN; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS00194; THIOREDOXIN_1; 1; .
PROSITEPS51352; THIOREDOXIN_2; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server