World-2DPAGE Home
Home  |  Contact

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P11352




SWISS-2DPAGE:  P11352


P11352


General information about the entry
View entry in simple text format
Entry nameGPX1_MOUSE
Primary accession numberP11352
integrated into SWISS-2DPAGE on June 30, 1999 (release 10)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;.
Gene nameName=Gpx1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=6.03; Mw=22834  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEIPI00319652; IPI00319652.
REPRODUCTION-2DPAGEP11352; P11352.
UniProtKB/Swiss-ProtP11352; GPX1_MOUSE.
World-2DPAGE RepositoryP11352; GPX1_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameGPX1_MOUSE
Primary accession numberP11352
Secondary accession number(s) P12079 Q544W3 Q9CR54
Sequence was last modified on February 26, 2008 (version 2)
Annotations were last modified on September 21, 2011 (version 123)
Name and origin of the protein
DescriptionRecName: Full=Glutathione peroxidase 1; Short=GPx-1; Short=GSHPx-1; EC=1.11.1.9; AltName: Full=Cellular glutathione peroxidase;
Gene nameName=Gpx1
Encoded onName=Gpx1
KeywordsAcetylation; Complete proteome; Cytoplasm; Oxidoreductase; Peroxidase; Phosphoprotein; Reference proteome; Selenocysteine.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX03920; CAA27558.1; -; Genomic_DNA
EMBLAK002245; BAC55244.1; -; mRNA
EMBLAK010999; BAC55252.1; -; mRNA
EMBLAK011019; BAC55253.1; -; mRNA
EMBLAK028171; BAC55257.1; -; mRNA
EMBLAK150548; BAE29650.1; -; mRNA
EMBLAK154833; BAE32862.1; -; mRNA
EMBLAK160388; BAE35760.1; -; mRNA
EMBLX15667; CAB43535.1; ALT_SEQ; mRNA
IPIIPI00319652; -; .
PIRA25106; OPMSE; .
PIRS05317; S05317; .
RefSeqNP_032186.2; NM_008160.6; .
UniGeneMm.1090; -; .
ProteinModelPortalP11352; -; .
SMRP11352; 11-195; .
STRINGP11352; -; .
PeroxiBase3709; MmGPx01; .
PhosphoSiteP11352; -; .
SWISS-2DPAGEP11352; -; .
REPRODUCTION-2DPAGEIPI00319652; -; .
REPRODUCTION-2DPAGEP11352; -; .
PRIDEP11352; -; .
EnsemblENSMUST00000082429; ENSMUSP00000081010; ENSMUSG00000063856; .
GeneID14775; -; .
KEGGmmu:14775; -; .
CTD2876; -; .
MGIMGI:104887; Gpx1; .
eggNOGmaNOG14464; -; .
HOGENOMHBG648990; -; .
HOVERGENHBG004333; -; .
InParanoidP11352; -; .
OMACRNDISW; -; .
OrthoDBEOG4SBF08; -; .
PhylomeDBP11352; -; .
NextBio286877; -; .
ArrayExpressP11352; -; .
BgeeP11352; -; .
CleanExMM_GPX1; -; .
GenevestigatorP11352; -; .
GermOnlineENSMUSG00000063856; Mus musculus; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0004602; F:glutathione peroxidase activity; IDA:MGI; .
GOGO:0060055; P:angiogenesis involved in wound healing; IMP:MGI; .
GOGO:0043534; P:blood vessel endothelial cell migration; IMP:MGI; .
GOGO:0001885; P:endothelial cell development; IMP:MGI; .
GOGO:0045444; P:fat cell differentiation; IMP:MGI; .
GOGO:0060047; P:heart contraction; IMP:MGI; .
GOGO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI; .
GOGO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI; .
GOGO:0051450; P:myoblast proliferation; IMP:MGI; .
GOGO:0014902; P:myotube differentiation; IMP:MGI; .
GOGO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI; .
GOGO:0018158; P:protein oxidation; IMP:MGI; .
GOGO:0043523; P:regulation of neuron apoptosis; IMP:MGI; .
GOGO:0033194; P:response to hydroperoxide; IMP:MGI; .
GOGO:0009636; P:response to toxin; IMP:MGI; .
GOGO:0009410; P:response to xenobiotic stimulus; IMP:MGI; .
GOGO:0007605; P:sensory perception of sound; IMP:MGI; .
GOGO:0048741; P:skeletal muscle fiber development; IMP:MGI; .
GOGO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI; .
GOGO:0006641; P:triglyceride metabolic process; IMP:MGI; .
GOGO:0042311; P:vasodilation; IMP:MGI; .
InterProIPR000889; Glutathione_peroxidase; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 1; .
PANTHERPTHR11592; Glut_peroxidase; 1; .
PfamPF00255; GSHPx; 1; .
PIRSFPIRSF000303; Glutathion_perox; 1; .
PRINTSPR01011; GLUTPROXDASE; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
PROSITEPS00460; GLUTATHIONE_PEROXID_1; 1; .
PROSITEPS00763; GLUTATHIONE_PEROXID_2; 1; .
PROSITEPS51355; GLUTATHIONE_PEROXID_3; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server