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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P11413



General information about the entry
View entry in simple text format
Entry nameG6PD_HUMAN
Primary accession numberP11413
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 1, 2000 (version 1)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=;.
Gene nameName=G6PD
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
MEDLINE=79188222; PubMed=109131; [NCBI, ExPASy, EBI, Israel, Japan]
Edwards J., Anderson N.G., Nance S.L., Anderson N.L.
''''''Red cell proteins. I. Two-dimensional mapping of human erythrocyte lysate proteins'';'';''
Blood 53(1):1121-1132(1979)
2D PAGE maps for identified proteins
How to interpret a protein

RBC_HUMAN {Red blood cells}
Homo sapiens (Human)
Tissue: Erythrocyte
  map experimental info
  protein estimated location

pI=6.05; Mw=51388
pI=5.91; Mw=51258
pI=5.81; Mw=51129
pI=5.68; Mw=51001

17 VARIANTS [1].

MAPPING (identification):

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP11413; G6PD_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameG6PD_HUMAN
Primary accession numberP11413
Secondary accession number(s) D3DWX9 Q16000 Q16765 Q8IU70 Q8IU88 Q8IUA6 Q96PQ2
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on September 21, 2011 (version 167)
Name and origin of the protein
DescriptionRecName: Full=Glucose-6-phosphate 1-dehydrogenase; Short=G6PD; EC=;
Gene nameName=G6PD
Encoded onName=G6PD
Keywords3D-structure; Acetylation; Alternative splicing; Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Disease mutation; Glucose metabolism; Hereditary hemolytic anemia; NADP; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX03674; CAA27309.1; -; mRNA
EMBLM65234; AAA63175.1; ALT_INIT; Genomic_DNA
EMBLM26749; AAA63175.1; JOINED; Genomic_DNA
EMBLM26750; AAA63175.1; JOINED; Genomic_DNA
EMBLM65225; AAA63175.1; JOINED; Genomic_DNA
EMBLM65226; AAA63175.1; JOINED; Genomic_DNA
EMBLM65227; AAA63175.1; JOINED; Genomic_DNA
EMBLM65228; AAA63175.1; JOINED; Genomic_DNA
EMBLM65229; AAA63175.1; JOINED; Genomic_DNA
EMBLM65230; AAA63175.1; JOINED; Genomic_DNA
EMBLM65231; AAA63175.1; JOINED; Genomic_DNA
EMBLM65233; AAA63175.1; JOINED; Genomic_DNA
EMBLM65232; AAA63175.1; JOINED; Genomic_DNA
EMBLM21248; AAA52500.1; -; mRNA
EMBLM19866; AAA52501.1; -; mRNA
EMBLX55448; CAA39089.1; -; Genomic_DNA
EMBLL44140; AAA92653.1; -; Genomic_DNA
EMBLAF277315; AAL27011.1; -; Genomic_DNA
EMBLCH471172; EAW72682.1; -; Genomic_DNA
EMBLCH471172; EAW72686.1; -; Genomic_DNA
EMBLBC000337; AAH00337.1; -; mRNA
EMBLM27940; AAA52504.1; -; mRNA
EMBLS58359; AAB26169.1; -; mRNA
EMBLX53815; CAA37811.1; -; Genomic_DNA
EMBLS64462; AAB20299.1; -; Genomic_DNA
EMBLAY158096; AAN76367.1; -; Genomic_DNA
EMBLAY158097; AAN76368.1; -; Genomic_DNA
EMBLAY158098; AAN76369.1; -; Genomic_DNA
EMBLAY158099; AAN76370.1; -; Genomic_DNA
EMBLAY158100; AAN76371.1; -; Genomic_DNA
EMBLAY158101; AAN76372.1; -; Genomic_DNA
EMBLAY158102; AAN76373.1; -; Genomic_DNA
EMBLAY158103; AAN76374.1; -; Genomic_DNA
EMBLAY158104; AAN76375.1; -; Genomic_DNA
EMBLAY158105; AAN76376.1; -; Genomic_DNA
EMBLAY158106; AAN76377.1; -; Genomic_DNA
EMBLAY158107; AAN76378.1; -; Genomic_DNA
EMBLAY158108; AAN76379.1; -; Genomic_DNA
EMBLAY158109; AAN76380.1; -; Genomic_DNA
EMBLAY158110; AAN76381.1; -; Genomic_DNA
EMBLAY158111; AAN76382.1; -; Genomic_DNA
EMBLAY158112; AAN76383.1; -; Genomic_DNA
EMBLAY158113; AAN76384.1; -; Genomic_DNA
EMBLAY158114; AAN76385.1; -; Genomic_DNA
EMBLAY158115; AAN76386.1; -; Genomic_DNA
EMBLAY158116; AAN76387.1; -; Genomic_DNA
EMBLAY158117; AAN76388.1; -; Genomic_DNA
EMBLAY158118; AAN76389.1; -; Genomic_DNA
EMBLAY158119; AAN76390.1; -; Genomic_DNA
EMBLAY158120; AAN76391.1; -; Genomic_DNA
EMBLAY158121; AAN76392.1; -; Genomic_DNA
EMBLAY158122; AAN76393.1; -; Genomic_DNA
EMBLAY158123; AAN76394.1; -; Genomic_DNA
EMBLAY158124; AAN76395.1; -; Genomic_DNA
EMBLAY158125; AAN76396.1; -; Genomic_DNA
EMBLAY158126; AAN76397.1; -; Genomic_DNA
EMBLAY158127; AAN76398.1; -; Genomic_DNA
EMBLAY158128; AAN76399.1; -; Genomic_DNA
EMBLAY158129; AAN76400.1; -; Genomic_DNA
EMBLAY158130; AAN76401.1; -; Genomic_DNA
EMBLAY158131; AAN76402.1; -; Genomic_DNA
EMBLAY158132; AAN76403.1; -; Genomic_DNA
EMBLAY158133; AAN76404.1; -; Genomic_DNA
EMBLAY158134; AAN76405.1; -; Genomic_DNA
EMBLAY158135; AAN76406.1; -; Genomic_DNA
EMBLAY158136; AAN76407.1; -; Genomic_DNA
EMBLAY158137; AAN76408.1; -; Genomic_DNA
EMBLAY158138; AAN76409.1; -; Genomic_DNA
EMBLAY158139; AAN76410.1; -; Genomic_DNA
EMBLAY158140; AAN76411.1; -; Genomic_DNA
EMBLAY158141; AAN76412.1; -; Genomic_DNA
EMBLAY158142; AAN76413.1; -; Genomic_DNA
EMBLM12996; AAA52499.1; -; mRNA
EMBLM23423; AAB59390.1; -; Genomic_DNA
IPIIPI00216008; -; .
IPIIPI00289800; -; .
IPIIPI00853547; -; .
PIRA40309; DEHUG6; .
RefSeqNP_000393.4; NM_000402.3; .
RefSeqNP_001035810.1; NM_001042351.1; .
UniGeneHs.461047; -; .
UniGeneHs.684904; -; .
PDB1QKI; X-ray; 3.00 A; A/B/C/D/E/F/G/H=2-515
PDB2BH9; X-ray; 2.50 A; A=28-514
PDB2BHL; X-ray; 2.90 A; A/B=28-515
PDBsum1QKI; -; .
PDBsum2BH9; -; .
PDBsum2BHL; -; .
ProteinModelPortalP11413; -; .
SMRP11413; 28-515; .
STRINGP11413; -; .
PhosphoSiteP11413; -; .
SWISS-2DPAGEP11413; -; .
PRIDEP11413; -; .
EnsemblENST00000291567; ENSP00000291567; ENSG00000160211; .
EnsemblENST00000393562; ENSP00000377192; ENSG00000160211; .
EnsemblENST00000393564; ENSP00000377194; ENSG00000160211; .
GeneID2539; -; .
KEGGhsa:2539; -; .
UCSCuc004fly.1; human; .
CTD2539; -; .
GeneCardsGC0XM142336; -; .
H-InvDBHIX0203292; -; .
HGNCHGNC:4057; G6PD; .
HPAHPA000247; -; .
HPAHPA000834; -; .
MIM305900; gene+phenotype; .
neXtProtNX_P11413; -; .
Orphanet362; Glucose-6-phosphate-dehydrogenase deficiency; .
PharmGKBPA28469; -; .
HOVERGENHBG000856; -; .
OrthoDBEOG4VHK69; -; .
PhylomeDBP11413; -; .
ReactomeREACT_474; Metabolism of carbohydrates; .
NextBio10021; -; .
ArrayExpressP11413; -; .
BgeeP11413; -; .
CleanExHS_G6PD; -; .
GenevestigatorP11413; -; .
GermOnlineENSG00000160211; Homo sapiens; .
GOGO:0005813; C:centrosome; IDA:HPA; .
GOGO:0005829; C:cytosol; IDA:BHF-UCL; .
GOGO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL; .
GOGO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA; .
GOGO:0005536; F:glucose binding; IDA:BHF-UCL; .
GOGO:0004345; F:glucose-6-phosphate dehydrogenase activity; IMP:BHF-UCL; .
GOGO:0050661; F:NADP binding; IDA:BHF-UCL; .
GOGO:0042803; F:protein homodimerization activity; IPI:BHF-UCL; .
GOGO:0034599; P:cellular response to oxidative stress; IMP:BHF-UCL; .
GOGO:0006695; P:cholesterol biosynthetic process; IMP:BHF-UCL; .
GOGO:0001816; P:cytokine production; IMP:BHF-UCL; .
GOGO:0043249; P:erythrocyte maturation; IMP:BHF-UCL; .
GOGO:0051156; P:glucose 6-phosphate metabolic process; IMP:BHF-UCL; .
GOGO:0006749; P:glutathione metabolic process; IMP:BHF-UCL; .
GOGO:0010734; P:negative regulation of protein glutathionylation; IMP:BHF-UCL; .
GOGO:0009051; P:pentose-phosphate shunt; oxidative branch; IMP:BHF-UCL
GOGO:0046390; P:ribose phosphate biosynthetic process; IMP:BHF-UCL; .
InterProIPR001282; G6P_DH; .
InterProIPR019796; G6P_DH_AS; .
InterProIPR022675; G6P_DH_C; .
InterProIPR022674; G6P_DH_NAD-bd; .
InterProIPR016040; NAD(P)-bd_dom; .
Gene3DG3DSA:; NAD(P)-bd; 1; .
PfamPF02781; G6PD_C; 1; .
PfamPF00479; G6PD_N; 1; .
PIRSFPIRSF000110; G6PD; 1; .
TIGRFAMsTIGR00871; Zwf; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server