World-2DPAGE Home
Home  |  Contact


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P11499




SWISS-2DPAGE:  P11499


P11499


General information about the entry
View entry in simple text format
Entry nameHS90B_MOUSE
Primary accession numberP11499
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein HSP 90-beta; AltName: Full=Heat shock 84 kDa; Short=HSP 84; Short=HSP84; AltName: Full=Tumor-specific transplantation 84 kDa antigen; Short=TSTA;.
Gene nameName=Hsp90ab1
Synonyms=Hsp84, Hsp84-1, Hspcb
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.02; Mw=82305

MAPPING (identification):
MATCHING [2] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location
 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=5.04; Mw=85913

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [2].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=5.02; Mw=85913
pI=5.04; Mw=85913
pI=4.99; Mw=85301

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP11499; HS90B_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameHS90B_MOUSE
Primary accession numberP11499
Secondary accession number(s) O89078 Q3UIQ7
Sequence was last modified on July 27, 2011 (version 3)
Annotations were last modified on October 19, 2011 (version 132)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein HSP 90-beta; AltName: Full=Heat shock 84 kDa; Short=HSP 84; Short=HSP84; AltName: Full=Tumor-specific transplantation 84 kDa antigen; Short=TSTA;
Gene nameName=Hsp90ab1
Synonyms=Hsp84, Hsp84-1, Hspcb
Encoded onName=Hsp90ab1; Synonyms=Hsp84, Hsp84-1, Hspcb
KeywordsAcetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Reference proteome; S-nitrosylation; Stress response; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM36829; AAA37866.1; -; mRNA
EMBLM18186; AAA37865.1; -; mRNA
EMBLAK146809; BAE27449.1; -; mRNA
EMBLAC163677; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLU89426; AAC36532.1; -; mRNA
EMBLS46109; AAB23704.1; -; mRNA
IPIIPI00554929; -; .
PIRA35569; HHMS84; .
PIRI57523; I57523; .
RefSeqNP_032328.2; NM_008302.3; .
UniGeneMm.2180; -; .
ProteinModelPortalP11499; -; .
DIPDIP-461N; -; .
IntActP11499; 8; .
MINTMINT-152750; -; .
STRINGP11499; -; .
PhosphoSiteP11499; -; .
SWISS-2DPAGEP11499; -; .
PRIDEP11499; -; .
EnsemblENSMUST00000024739; ENSMUSP00000024739; ENSMUSG00000023944; .
GeneID15516; -; .
MGIMGI:96247; Hsp90ab1; .
eggNOGroNOG11308; -; .
HOGENOMHBG631012; -; .
HOVERGENHBG007374; -; .
InParanoidP11499; -; .
OrthoDBEOG42V8FM; -; .
PhylomeDBP11499; -; .
ArrayExpressP11499; -; .
BgeeP11499; -; .
GenevestigatorP11499; -; .
GermOnlineENSMUSG00000023944; Mus musculus; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0005739; C:mitochondrion; IDA:MGI; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0030235; F:nitric-oxide synthase regulator activity; ISS:UniProtKB; .
GOGO:0030911; F:TPR domain binding; ISS:UniProtKB; .
GOGO:0051082; F:unfolded protein binding; IEA:InterPro; .
GOGO:0001890; P:placenta development; IMP:MGI; .
GOGO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:UniProtKB; .
GOGO:0006457; P:protein folding; IEA:InterPro; .
GOGO:0006950; P:response to stress; IEA:UniProtKB-KW; .
InterProIPR003594; ATPase-like_ATP-bd; .
InterProIPR019805; Heat_shock_protein_90_CS; .
InterProIPR001404; Hsp90; .
InterProIPR020575; Hsp90_N; .
InterProIPR020568; Ribosomal_S5_D2-typ_fold; .
Gene3DG3DSA:3.30.565.10; ATP_bd_ATPase; 2; .
PANTHERPTHR11528; Hsp90; 1; .
PfamPF02518; HATPase_c; 1; .
PfamPF00183; HSP90; 1; .
PIRSFPIRSF002583; Hsp90; 1; .
PRINTSPR00775; HEATSHOCK90; .
SMARTSM00387; HATPase_c; 1; .
SUPFAMSSF55874; ATP_bd_ATPase; 1; .
SUPFAMSSF54211; Ribosomal_S5_D2-typ_fold; 1; .
PROSITEPS00298; HSP90; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server