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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P11679



General information about the entry
View entry in simple text format
Entry nameK2C8_MOUSE
Primary accession numberP11679
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 2)
General Annotations were last modified on May 19, 2011 (version 10)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type II cytoskeletal 8; AltName: Full=Cytokeratin endo A; AltName: Full=Cytokeratin-8; Short=CK-8; AltName: Full=Keratin-8; Short=K8; AltName: Full=Type-II keratin Kb8;.
Gene nameName=Krt8
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ISLETS_MOUSE {Pancreatic islet cells}
Mus musculus (Mouse)
Tissue: Pancreatic islet
  map experimental info
  protein estimated location

pI=5.36; Mw=55957  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Mus musculus (Mouse)
Tissue: Liver
  map experimental info
  protein estimated location

pI=5.70; Mw=53059

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP11679; K2C8_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameK2C8_MOUSE
Primary accession numberP11679
Secondary accession number(s) Q3KQK5 Q3TGI1 Q3TJE1 Q3TKY7 Q61463 Q61518 Q61519
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on September 21, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type II cytoskeletal 8; AltName: Full=Cytokeratin endo A; AltName: Full=Cytokeratin-8; Short=CK-8; AltName: Full=Keratin-8; Short=K8; AltName: Full=Type-II keratin Kb8;
Gene nameName=Krt8
Encoded onName=Krt8; Synonyms=Krt2-8
KeywordsAcetylation; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Glycoprotein; Intermediate filament; Keratin; Nucleus; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX12789; CAA31278.1; -; mRNA
EMBLX15662; CAA33697.1; -; Genomic_DNA
EMBLM21836; AAA37550.1; -; mRNA
EMBLM21836; AAA37551.1; ALT_INIT; mRNA
EMBLM22831; AAA37548.1; -; mRNA
EMBLD90360; BAA14375.1; -; Genomic_DNA
EMBLAK077597; BAC36888.1; -; mRNA
EMBLAK145546; BAE26499.1; -; mRNA
EMBLAK145679; BAE26585.1; -; mRNA
EMBLAK145777; BAE26646.1; -; mRNA
EMBLAK146948; BAE27557.1; -; mRNA
EMBLAK147044; BAE27630.1; -; mRNA
EMBLAK166737; BAE38980.1; -; mRNA
EMBLAK166768; BAE39006.1; -; mRNA
EMBLAK166854; BAE39072.1; -; mRNA
EMBLAK166960; BAE39143.1; -; mRNA
EMBLAK166993; BAE39172.1; -; mRNA
EMBLAK167120; BAE39268.1; -; mRNA
EMBLAK167269; BAE39382.1; -; mRNA
EMBLAK167471; BAE39554.1; -; mRNA
EMBLAK168522; BAE40401.1; -; mRNA
EMBLAK168540; BAE40418.1; -; mRNA
EMBLAK168561; BAE40434.1; -; mRNA
EMBLAK168726; BAE40567.1; -; mRNA
EMBLAK168910; BAE40723.1; -; mRNA
EMBLAK169136; BAE40915.1; -; mRNA
EMBLAK169691; BAE41308.1; -; mRNA
EMBLBC094009; AAH94009.1; -; mRNA
EMBLBC106154; AAI06155.1; -; mRNA
IPIIPI00322209; -; .
PIRJS0658; JS0658; .
PIRJT0407; JT0407; .
PIRS05474; S05474; .
RefSeqNP_112447.2; NM_031170.2; .
UniGeneMm.358618; -; .
ProteinModelPortalP11679; -; .
SMRP11679; 95-132; 137-244; 261-403
STRINGP11679; -; .
PhosphoSiteP11679; -; .
SWISS-2DPAGEP11679; -; .
PRIDEP11679; -; .
EnsemblENSMUST00000023952; ENSMUSP00000023952; ENSMUSG00000049382; .
GeneID16691; -; .
KEGGmmu:16691; -; .
UCSCuc007xui.1; mouse; .
CTD3856; -; .
MGIMGI:96705; Krt8; .
eggNOGroNOG13579; -; .
GeneTreeENSGT00550000074388; -; .
HOVERGENHBG013015; -; .
InParanoidP11679; -; .
OrthoDBEOG4XKV78; -; .
PhylomeDBP11679; -; .
NextBio290445; -; .
ArrayExpressP11679; -; .
BgeeP11679; -; .
CleanExMM_KRT8; -; .
GenevestigatorP11679; -; .
GermOnlineENSMUSG00000049382; Mus musculus; .
GOGO:0045095; C:keratin filament; IEA:InterPro; .
GOGO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; .
GOGO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell; .
GOGO:0042383; C:sarcolemma; IDA:MGI; .
GOGO:0030018; C:Z disc; IDA:MGI; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0006915; P:apoptosis; IMP:MGI; .
GOGO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI; .
GOGO:0000904; P:cell morphogenesis involved in differentiation; TAS:UniProtKB; .
GOGO:0051707; P:response to other organism; IMP:MGI; .
GOGO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:MGI; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR018039; Intermediate_filament_CS; .
InterProIPR003054; Keratin_II; .
InterProIPR009053; Prefoldin; .
PANTHERPTHR23239; IF; 1; .
PANTHERPTHR23239:SF18; Keratin_II; 1; .
PfamPF00038; Filament; 1; .
SUPFAMSSF46579; Prefoldin; 1; .
PROSITEPS00226; IF; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server