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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: P11725



General information about the entry
View entry in simple text format
Entry nameOTC_MOUSE
Primary accession numberP11725
integrated into SWISS-2DPAGE on October 31, 1999 (release 11)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Ornithine carbamoyltransferase, mitochondrial; EC=; AltName: Full=Ornithine transcarbamylase; Short=OTCase; Flags: Precursor;.
Gene nameName=Otc
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

Mus musculus (Mouse)
Tissue: Liver
  map experimental info
  protein estimated location

pI=6.80; Mw=36427  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP11725; OTC_MOUSE.
World-2DPAGE RepositoryP11725; OTC_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameOTC_MOUSE
Primary accession numberP11725
Sequence was last modified on October 1, 1989 (version 1)
Annotations were last modified on September 21, 2011 (version 113)
Name and origin of the protein
DescriptionRecName: Full=Ornithine carbamoyltransferase, mitochondrial; EC=; AltName: Full=Ornithine transcarbamylase; Short=OTCase; Flags: Precursor;
Gene nameName=Otc
Encoded onName=Otc
KeywordsAcetylation; Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Disease mutation; Mitochondrion; Reference proteome; Transferase; Transit peptide; Urea cycle.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM17030; AAA39865.1; -; mRNA
EMBLM12716; AAA39864.1; ALT_SEQ; Genomic_DNA
EMBLX07092; CAA30121.1; -; Genomic_DNA
EMBLX07093; CAA30121.1; JOINED; Genomic_DNA
EMBLX07094; CAA30121.1; JOINED; Genomic_DNA
EMBLX07095; CAA30121.1; JOINED; Genomic_DNA
EMBLX07096; CAA30121.1; JOINED; Genomic_DNA
EMBLX07097; CAA30121.1; JOINED; Genomic_DNA
EMBLX07098; CAA30121.1; JOINED; Genomic_DNA
EMBLX07099; CAA30121.1; JOINED; Genomic_DNA
EMBLX07100; CAA30121.1; JOINED; Genomic_DNA
IPIIPI00116603; -; .
PIRA43609; OWMS; .
RefSeqNP_032795.1; NM_008769.3; .
UniGeneMm.2611; -; .
ProteinModelPortalP11725; -; .
SMRP11725; 34-354; .
STRINGP11725; -; .
PhosphoSiteP11725; -; .
SWISS-2DPAGEP11725; -; .
PRIDEP11725; -; .
EnsemblENSMUST00000049910; ENSMUSP00000056152; ENSMUSG00000031173; .
GeneID18416; -; .
KEGGmmu:18416; -; .
CTD5009; -; .
MGIMGI:97448; Otc; .
eggNOGroNOG05084; -; .
HOGENOMHBG579429; -; .
HOVERGENHBG007881; -; .
InParanoidP11725; -; .
OrthoDBEOG4GB76C; -; .
PhylomeDBP11725; -; .
NextBio294052; -; .
ArrayExpressP11725; -; .
BgeeP11725; -; .
CleanExMM_OTC; -; .
GenevestigatorP11725; -; .
GermOnlineENSMUSG00000031173; Mus musculus; .
GOGO:0005743; C:mitochondrial inner membrane; IDA:MGI; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0009348; C:ornithine carbamoyltransferase complex; IEA:InterPro; .
GOGO:0004585; F:ornithine carbamoyltransferase activity; IEA:EC; .
GOGO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW; .
GOGO:0000050; P:urea cycle; IEA:UniProtKB-KW; .
InterProIPR006132; Asp/Orn_carbamoyltranf_P-bd; .
InterProIPR006130; Asp/Orn_carbamoylTrfase; .
InterProIPR006131; Asp_carbamoyltransf_Asp/Orn-bd; .
InterProIPR002292; Orn_carbamltrans; .
PfamPF00185; OTCace; 1; .
PfamPF02729; OTCace_N; 1; .
SUPFAMSSF53671; Asp/Orn_carbamoyltranf; 1; .
TIGRFAMsTIGR00658; Orni_carb_tr; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server