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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P17661




SWISS-2DPAGE:  P17661


P17661


General information about the entry
View entry in simple text format
Entry nameDESM_HUMAN
Primary accession numberP17661
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=Desmin;.
Gene nameName=DES
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
Comments
  • SUBUNIT: Homopolymer
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=4.99; Mw=43286  [identification data]

MAPPING (identification):
MALDI tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
HSC-2DPAGEP17661; HUMAN.
REPRODUCTION-2DPAGEP17661; P17661.
REPRODUCTION-2DPAGEIPI00465084; IPI00465084.
UCD-2DPAGEP17661; DESM_HUMAN.
UniProtKB/Swiss-ProtP17661; DESM_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDESM_HUMAN
Primary accession numberP17661
Secondary accession number(s) Q15787 Q8IZR1 Q8IZR6 Q8NES2 Q8NEU6 Q8TAC4 Q8TCX2 Q8TD99 Q9UHN5 Q9UJ80
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on October 19, 2011 (version 125)
Name and origin of the protein
DescriptionRecName: Full=Desmin;
Gene nameName=DES
Encoded onName=DES
KeywordsCardiomyopathy; Coiled coil; Complete proteome; Cytoplasm; Desmin-related myopathy; Disease mutation; Intermediate filament; Muscle protein; Myofibrillar myopathy; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM63391; AAA99221.1; -; Genomic_DNA
EMBLU59167; AAC50680.1; -; mRNA
EMBLAF137053; AAF15400.1; -; mRNA
EMBLAF486807; AAL93205.1; -; mRNA
EMBLAF487828; AAL99078.1; -; mRNA
EMBLAF521879; AAN15036.1; -; mRNA
EMBLAF527578; AAN37810.1; -; mRNA
EMBLAY083345; AAL99215.1; -; mRNA
EMBLAY114212; AAM47026.1; -; Genomic_DNA
EMBLAY125465; AAM95238.1; -; mRNA
EMBLBC032116; AAH32116.1; -; mRNA
EMBLAJ132926; CAB62389.1; -; mRNA
IPIIPI00465084; -; .
PIRJE0063; DMHU; .
RefSeqNP_001918.3; NM_001927.3; .
UniGeneHs.594952; -; .
ProteinModelPortalP17661; -; .
SMRP17661; 106-143; 153-254; 268-411
IntActP17661; 1; .
MINTMINT-215829; -; .
STRINGP17661; -; .
PhosphoSiteP17661; -; .
SWISS-2DPAGEP17661; -; .
REPRODUCTION-2DPAGEIPI00465084; -; .
REPRODUCTION-2DPAGEP17661; -; .
UCD-2DPAGEP17661; -; .
PRIDEP17661; -; .
EnsemblENST00000373960; ENSP00000363071; ENSG00000175084; .
GeneID1674; -; .
KEGGhsa:1674; -; .
UCSCuc002vll.1; human; .
CTD1674; -; .
GeneCardsGC02P212136; -; .
H-InvDBHIX0200296; -; .
HGNCHGNC:2770; DES; .
HPACAB000034; -; .
HPAHPA018803; -; .
MIM125660; gene; .
MIM181400; phenotype; .
MIM601419; phenotype; .
MIM604765; phenotype; .
neXtProtNX_P17661; -; .
Orphanet98909; Desminopathy; .
Orphanet154; Familial isolated dilated cardiomyopathy; .
Orphanet85146; Scapuloperoneal amyotrophy; .
PharmGKBPA27253; -; .
eggNOGprNOG08072; -; .
HOVERGENHBG013015; -; .
InParanoidP17661; -; .
OMASSEMHSK; -; .
OrthoDBEOG4H9XKM; -; .
PhylomeDBP17661; -; .
Pathway_Interaction_DBaurora_b_pathway; Aurora B signaling; .
ReactomeREACT_17044; Muscle contraction; .
NextBio6888; -; .
ArrayExpressP17661; -; .
BgeeP17661; -; .
GenevestigatorP17661; -; .
GermOnlineENSG00000175084; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0030018; C:Z disc; IDA:MGI; .
GOGO:0051419; F:nebulin binding; IPI:BHF-UCL; .
GOGO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc; .
GOGO:0007010; P:cytoskeleton organization; TAS:ProtInc; .
GOGO:0030049; P:muscle filament sliding; TAS:Reactome; .
GOGO:0008016; P:regulation of heart contraction; TAS:ProtInc; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR006821; Intermed_filament_DNA-bd; .
InterProIPR018039; Intermediate_filament_CS; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PfamPF04732; Filament_head; 1; .
PROSITEPS00226; IF; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server