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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis


Searching in 'SWISS-2DPAGE' for entry matching: P17742




SWISS-2DPAGE:  P17742

P17742


General information about the entry
View entry in simple text format
Entry namePPIA_MOUSE
Primary accession numberP17742
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 4)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Peptidyl-prolyl cis-trans isomerase A; Short=PPIase A; EC=5.2.1.8; AltName: Full=Cyclophilin A; AltName: Full=Cyclosporin A-binding protein; AltName: Full=Rotamase A; AltName: Full=SP18;.
Gene nameName=Ppia
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
[2]   MAPPING ON GEL
PubMed=11503206; [NCBI, ExPASy, EBI, Israel, Japan]
Lanne B., Potthast F., Hoglund A., Brockenhuus Von Lowenhielm H., Nystrom A.-C., Nilsson F., Dahllof B.
''''''Thiourea enhances mapping of the proteome from murine white adipose tissue'';'';''
Proteomics 1(1):819-828(2001)
[3]   MAPPING ON GEL
Tonella L., Hoogland C., Sanchez J.-C.
Submitted (OCT-2001) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location 		 
BAT_MOUSE

MAP LOCATIONS:
pI=7.75; Mw=14235

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location 		 
LIVER_MOUSE

MAP LOCATIONS:
pI=7.18; Mw=15283  [identification data]
pI=7.60; Mw=15061  [identification data]
pI=7.01; Mw=14967

MAPPING (identification):
SPOTS 2D-0014IC:, 2D-0014IH: Peptide mass fingerprinting [1]; SPOTS 2D-0014IH:,2D-0014IM: MICROSEQUENCING [1].



MUSCLE_MOUSE {Gastrocnemius muscle}
Mus musculus (Mouse)
Tissue: Gastrocnemius
MUSCLE_MOUSE
  map experimental info
  protein estimated location 		 
MUSCLE_MOUSE

MAP LOCATIONS:
pI=6.93; Mw=14967  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location 		 
WAT_MOUSE

MAP LOCATIONS:
pI=7.04; Mw=13816
pI=7.46; Mw=13456
pI=6.97; Mw=13338

MAPPING (identification):
SPOT 2D-001CDY: GEL MATCHING [3] WITH WAT_MOUSE 2-DE MAP FROM LANNE ET AL [2]; SPOTS 1CE*: MATCHING WITH THE MOUSE LIVER MASTER GEL [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEP17742; P17742.
UCD-2DPAGEP17742; PPIA_MOUSE.
UniProtKB/Swiss-ProtP17742; PPIA_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePPIA_MOUSE
Primary accession numberP17742
Secondary accession number(s) Q9CWJ5 Q9R137
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on September 21, 2011 (version 128)
Name and origin of the protein
DescriptionRecName: Full=Peptidyl-prolyl cis-trans isomerase A; Short=PPIase A; EC=5.2.1.8; AltName: Full=Cyclophilin A; AltName: Full=Cyclosporin A-binding protein; AltName: Full=Rotamase A; AltName: Full=SP18;
Gene nameName=Ppia
Encoded onName=Ppia
KeywordsAcetylation; Complete proteome; Cyclosporin; Cytoplasm; Direct protein sequencing; Isomerase; Isopeptide bond; Phosphoprotein; Reference proteome; Rotamase; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX52803; CAA36989.1; -; mRNA
EMBLAK002236; BAB21954.1; -; mRNA
EMBLAK007981; BAB25387.1; -; mRNA
EMBLAK010649; BAB27089.1; -; mRNA
EMBLAK012531; BAB28300.1; -; mRNA
EMBLAK012663; BAB28392.1; -; mRNA
EMBLAK028210; BAC25817.1; -; mRNA
EMBLBC083076; AAH83076.1; -; mRNA
EMBLAF171073; AAD50996.1; -; Genomic_DNA
IPIIPI00554989; -; .
PIRS10327; CSMSA; .
RefSeqNP_032933.1; NM_008907.1; .
UniGeneMm.5246; -; .
ProteinModelPortalP17742; -; .
SMRP17742; 2-164; .
IntActP17742; 3; .
STRINGP17742; -; .
PhosphoSiteP17742; -; .
SWISS-2DPAGEP17742; -; .
REPRODUCTION-2DPAGEP17742; -; .
UCD-2DPAGEP17742; -; .
PRIDEP17742; -; .
EnsemblENSMUST00000071781; ENSMUSP00000071686; ENSMUSG00000062933; .
EnsemblENSMUST00000132846; ENSMUSP00000117987; ENSMUSG00000071866; .
GeneID268373; -; .
KEGGmmu:268373; -; .
CTD5478; -; .
MGIMGI:97749; Ppia; .
eggNOGroNOG10445; -; .
HOVERGENHBG001065; -; .
InParanoidP17742; -; .
OMAIEDCGEL; -; .
OrthoDBEOG4DJJXN; -; .
PhylomeDBP17742; -; .
NextBio392255; -; .
ArrayExpressP17742; -; .
CleanExMM_PPIA; -; .
GenevestigatorP17742; -; .
GermOnlineENSMUSG00000059583; Mus musculus; .
GermOnlineENSMUSG00000062933; Mus musculus; .
GermOnlineENSMUSG00000071866; Mus musculus; .
GOGO:0005829; C:cytosol; ISS:UniProtKB; .
GOGO:0005634; C:nucleus; ISS:UniProtKB; .
GOGO:0042277; F:peptide binding; IEA:UniProtKB-KW; .
GOGO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW; .
GOGO:0006457; P:protein folding; IEA:UniProtKB-KW; .
GOGO:0045069; P:regulation of viral genome replication; ISS:UniProtKB; .
InterProIPR015891; Cyclophilin-like; .
InterProIPR020892; Pep-Pro_Isoase_cyclophilin_CS; .
InterProIPR002130; PPIase_cyclophilin; .
Gene3DG3DSA:2.40.100.10; PPIase_cyclophilin; 1; .
PfamPF00160; Pro_isomerase; 1; .
PRINTSPR00153; CSAPPISMRASE; .
SUPFAMSSF50891; CSA_PPIase; 1; .
PROSITEPS00170; CSA_PPIASE_1; 1; .
PROSITEPS50072; CSA_PPIASE_2; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server