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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P19784




SWISS-2DPAGE:  P19784


P19784


General information about the entry
View entry in simple text format
Entry nameCSK22_HUMAN
Primary accession numberP19784
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 4)
Name and origin of the protein
DescriptionRecName: Full=Casein kinase II subunit alpha'; Short=CK II alpha'; EC=2.7.11.1;.
Gene nameName=CSNK2A2
Synonyms=CK2A2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
Comments
  • SUBUNIT: TETRAMER COMPOSED OF AN ALPHA CHAIN, AN ALPHA' AND TWO BETA CHAINS
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=38269  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP19784; CSK22_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCSK22_HUMAN
Primary accession numberP19784
Sequence was last modified on February 1, 1991 (version 1)
Annotations were last modified on October 19, 2011 (version 123)
Name and origin of the protein
DescriptionRecName: Full=Casein kinase II subunit alpha'; Short=CK II alpha'; EC=2.7.11.1;
Gene nameName=CSNK2A2
Synonyms=CK2A2
Encoded onName=CSNK2A2; Synonyms=CK2A2
Keywords3D-structure; Acetylation; ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase; Wnt signaling pathway.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM55268; AAA51548.1; -; mRNA
EMBLBC008812; AAH08812.1; -; mRNA
IPIIPI00020602; -; .
PIRB35838; B35838; .
RefSeqNP_001887.1; NM_001896.2; .
UniGeneHs.82201; -; .
PDB3E3B; X-ray; 3.20 A; X=1-334
PDB3OFM; X-ray; 2.00 A; A=1-350
PDB3RP0; X-ray; 3.00 A; A/B/C/D=331-350
PDBsum3E3B; -; .
PDBsum3OFM; -; .
PDBsum3RP0; -; .
ProteinModelPortalP19784; -; .
SMRP19784; 8-332; .
DIPDIP-318N; -; .
IntActP19784; 8; .
MINTMINT-5004107; -; .
STRINGP19784; -; .
PhosphoSiteP19784; -; .
SWISS-2DPAGEP19784; -; .
PeptideAtlasP19784; -; .
PRIDEP19784; -; .
EnsemblENST00000262506; ENSP00000262506; ENSG00000070770; .
GeneID1459; -; .
KEGGhsa:1459; -; .
UCSCuc002enc.1; human; .
CTD1459; -; .
GeneCardsGC16M044059; -; .
H-InvDBHIX0013086; -; .
HGNCHGNC:2459; CSNK2A2; .
MIM115442; gene; .
neXtProtNX_P19784; -; .
PharmGKBPA26959; -; .
eggNOGprNOG16169; -; .
GeneTreeENSGT00390000004215; -; .
HOGENOMHBG755340; -; .
HOVERGENHBG107282; -; .
InParanoidP19784; -; .
OMAPSWGNQD; -; .
OrthoDBEOG4J118H; -; .
PhylomeDBP19784; -; .
BRENDA2.7.11.1; 2681; .
Pathway_Interaction_DBnfkappabatypicalpathway; Atypical NF-kappaB pathway; .
Pathway_Interaction_DBp38alphabetadownstreampathway; Signaling mediated by p38-alpha and p38-beta; .
ReactomeREACT_18266; Axon guidance; .
NextBio5997; -; .
ArrayExpressP19784; -; .
BgeeP19784; -; .
CleanExHS_CSNK2A2; -; .
GenevestigatorP19784; -; .
GermOnlineENSG00000070770; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0047485; F:protein N-terminus binding; IPI:UniProtKB; .
GOGO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW; .
InterProIPR011009; Kinase-like_dom; .
InterProIPR000719; Prot_kinase_cat_dom; .
InterProIPR017441; Protein_kinase_ATP_BS; .
InterProIPR017442; Se/Thr_kinase-like_dom; .
InterProIPR008271; Ser/Thr_kinase_AS; .
InterProIPR002290; Ser/Thr_kinase_dom; .
PfamPF00069; Pkinase; 1; .
SMARTSM00220; S_TKc; 1; .
SUPFAMSSF56112; Kinase_like; 1; .
PROSITEPS00107; PROTEIN_KINASE_ATP; 1; .
PROSITEPS50011; PROTEIN_KINASE_DOM; 1; .
PROSITEPS00108; PROTEIN_KINASE_ST; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server