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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P23284




SWISS-2DPAGE:  P23284


P23284


General information about the entry
View entry in simple text format
Entry namePPIB_HUMAN
Primary accession numberP23284
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Peptidyl-prolyl cis-trans isomerase B; Short=PPIase B; EC=5.2.1.8; AltName: Full=CYP-S1; AltName: Full=Cyclophilin B; AltName: Full=Rotamase B; AltName: Full=S-cyclophilin; Short=SCYLP; Flags: Precursor;.
Gene nameName=PPIB
Synonyms=CYPB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=20347  [identification data]

MAPPING (identification):
Tandem mass spectrometry and peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP23284.
REPRODUCTION-2DPAGEIPI00646304; IPI00646304.
UniProtKB/Swiss-ProtP23284; PPIB_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePPIB_HUMAN
Primary accession numberP23284
Secondary accession number(s) A8K534 Q6IBH5 Q9BVK5
Sequence was last modified on November 25, 2008 (version 2)
Annotations were last modified on October 19, 2011 (version 123)
Name and origin of the protein
DescriptionRecName: Full=Peptidyl-prolyl cis-trans isomerase B; Short=PPIase B; EC=5.2.1.8; AltName: Full=CYP-S1; AltName: Full=Cyclophilin B; AltName: Full=Rotamase B; AltName: Full=S-cyclophilin; Short=SCYLP; Flags: Precursor;
Gene nameName=PPIB
Synonyms=CYPB
Encoded onName=PPIB; Synonyms=CYPB
Keywords3D-structure; Complete proteome; Cyclosporin; Direct protein sequencing; Disease mutation; Dwarfism; Endoplasmic reticulum; Glycoprotein; Isomerase; Osteogenesis imperfecta; Polymorphism; Reference proteome; Rotamase; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM63573; AAA36601.1; -; mRNA
EMBLAK291149; BAF83838.1; -; mRNA
EMBLCR456829; CAG33110.1; -; mRNA
EMBLAY962310; AAX44050.1; -; Genomic_DNA
EMBLAC100840; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471082; EAW77669.1; -; Genomic_DNA
EMBLBC001125; AAH01125.1; -; mRNA
EMBLBC008848; AAH08848.1; -; mRNA
EMBLBC020800; AAH20800.1; -; mRNA
EMBLBC032138; AAH32138.1; -; mRNA
EMBLM60857; AAA52150.1; ALT_INIT; mRNA
EMBLM60457; AAA35733.1; -; mRNA
IPIIPI00646304; -; .
PIRA39118; CSHUB; .
RefSeqNP_000933.1; NM_000942.4; .
UniGeneHs.434937; -; .
PDB1CYN; X-ray; 1.85 A; A=39-216
PDB3ICH; X-ray; 1.20 A; A=34-216
PDB3ICI; X-ray; 1.70 A; A/B=34-216
PDBsum1CYN; -; .
PDBsum3ICH; -; .
PDBsum3ICI; -; .
ProteinModelPortalP23284; -; .
SMRP23284; 32-216; .
IntActP23284; 10; .
MINTMINT-1142578; -; .
STRINGP23284; -; .
PhosphoSiteP23284; -; .
SWISS-2DPAGEP23284; -; .
Aarhus/Ghent-2DPAGE117; NEPHGE; .
OGPP23284; -; .
REPRODUCTION-2DPAGEIPI00646304; -; .
PRIDEP23284; -; .
EnsemblENST00000300026; ENSP00000300026; ENSG00000166794; .
GeneID5479; -; .
KEGGhsa:5479; -; .
UCSCuc002and.1; human; .
CTD5479; -; .
GeneCardsGC15M041272; -; .
H-InvDBHIX0012337; -; .
HGNCHGNC:9255; PPIB; .
HPACAB011487; -; .
HPAHPA012720; -; .
MIM123841; gene; .
MIM259440; phenotype; .
neXtProtNX_P23284; -; .
Orphanet216804; Osteogenesis imperfecta type 2; .
Orphanet216812; Osteogenesis imperfecta type 3; .
Orphanet216820; Osteogenesis imperfecta type 4; .
PharmGKBPA33580; -; .
eggNOGprNOG11714; -; .
GeneTreeENSGT00550000074120; -; .
HOGENOMHBG610621; -; .
HOVERGENHBG001065; -; .
InParanoidP23284; -; .
OMAKGPKVTA; -; .
OrthoDBEOG43XV4N; -; .
PhylomeDBP23284; -; .
Pathway_Interaction_DBsyndecan_1_pathway; Syndecan-1-mediated signaling events; .
DrugBankDB00172; L-Proline; .
NextBio21210; -; .
ArrayExpressP23284; -; .
BgeeP23284; -; .
CleanExHS_PPIB; -; .
GenevestigatorP23284; -; .
GermOnlineENSG00000166794; Homo sapiens; .
GOGO:0005788; C:endoplasmic reticulum lumen; NAS:UniProtKB; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0042277; F:peptide binding; IEA:UniProtKB-KW; .
GOGO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; NAS:UniProtKB; .
GOGO:0051082; F:unfolded protein binding; TAS:ProtInc; .
GOGO:0006457; P:protein folding; IEA:UniProtKB-KW; .
InterProIPR015891; Cyclophilin-like; .
InterProIPR020892; Pep-Pro_Isoase_cyclophilin_CS; .
InterProIPR002130; PPIase_cyclophilin; .
Gene3DG3DSA:2.40.100.10; PPIase_cyclophilin; 1; .
PfamPF00160; Pro_isomerase; 1; .
PRINTSPR00153; CSAPPISMRASE; .
SUPFAMSSF50891; CSA_PPIase; 1; .
PROSITEPS00170; CSA_PPIASE_1; 1; .
PROSITEPS50072; CSA_PPIASE_2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server