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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P24549




SWISS-2DPAGE:  P24549


P24549


General information about the entry
View entry in simple text format
Entry nameAL1A1_MOUSE
Primary accession numberP24549
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 2)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Retinal dehydrogenase 1; Short=RALDH 1; Short=RalDH1; EC=1.2.1.36; AltName: Full=ALDH-E1; AltName: Full=ALHDII; AltName: Full=Aldehyde dehydrogenase family 1 member A1; AltName: Full=Aldehyde dehydrogenase, cytosolic;.
Gene nameName=Aldh1a1
Synonyms=Ahd-2, Ahd2, Aldh1
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue
BAT_MOUSE
  map experimental info
  protein estimated location
 
BAT_MOUSE

MAP LOCATIONS:
pI=7.09; Mw=53128

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [1].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=7.83; Mw=52764
pI=7.30; Mw=52035
pI=7.49; Mw=52180
pI=7.65; Mw=52472
pI=7.09; Mw=52035

MAPPING (identification):
Peptide mass fingerprinting [1].



WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue
WAT_MOUSE
  map experimental info
  protein estimated location
 
WAT_MOUSE

MAP LOCATIONS:
pI=7.08; Mw=52138
pI=6.98; Mw=51975
pI=7.35; Mw=52138

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
REPRODUCTION-2DPAGEP24549; P24549.
REPRODUCTION-2DPAGEIPI00626662; IPI00626662.
UniProtKB/Swiss-ProtP24549; AL1A1_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameAL1A1_MOUSE
Primary accession numberP24549
Secondary accession number(s) Q7TQJ0 Q811J0
Sequence was last modified on January 23, 2007 (version 5)
Annotations were last modified on September 21, 2011 (version 119)
Name and origin of the protein
DescriptionRecName: Full=Retinal dehydrogenase 1; Short=RALDH 1; Short=RalDH1; EC=1.2.1.36; AltName: Full=ALDH-E1; AltName: Full=ALHDII; AltName: Full=Aldehyde dehydrogenase family 1 member A1; AltName: Full=Aldehyde dehydrogenase, cytosolic;
Gene nameName=Aldh1a1
Synonyms=Ahd-2, Ahd2, Aldh1
Encoded onName=Aldh1a1; Synonyms=Ahd-2, Ahd2, Aldh1
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; NAD; Oxidoreductase; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM74570; AAA37202.1; -; mRNA
EMBLM74571; AAA37203.1; -; Genomic_DNA
EMBLS75713; AAB32754.2; -; mRNA
EMBLS77047; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC044729; AAH44729.1; ALT_INIT; mRNA
EMBLBC054386; AAH54386.1; -; mRNA
IPIIPI00626662; -; .
PIRJQ1004; JQ1004; .
RefSeqNP_038495.2; NM_013467.3; .
UniGeneMm.250866; -; .
ProteinModelPortalP24549; -; .
SMRP24549; 9-501; .
IntActP24549; 1; .
STRINGP24549; -; .
PhosphoSiteP24549; -; .
SWISS-2DPAGEP24549; -; .
REPRODUCTION-2DPAGEIPI00626662; -; .
REPRODUCTION-2DPAGEP24549; -; .
PRIDEP24549; -; .
EnsemblENSMUST00000087638; ENSMUSP00000084918; ENSMUSG00000053279; .
GeneID11668; -; .
KEGGmmu:11668; -; .
UCSCuc008gyn.1; mouse; .
CTD216; -; .
MGIMGI:1353450; Aldh1a1; .
eggNOGroNOG04915; -; .
GeneTreeENSGT00550000074289; -; .
HOGENOMHBG752218; -; .
HOVERGENHBG000097; -; .
InParanoidP24549; -; .
OMANFPLVMF; -; .
OrthoDBEOG4Z8XW6; -; .
PhylomeDBP24549; -; .
BRENDA1.2.1.36; 3474; .
NextBio279287; -; .
ArrayExpressP24549; -; .
BgeeP24549; -; .
CleanExMM_ALDH1A1; -; .
GenevestigatorP24549; -; .
GermOnlineENSMUSG00000053279; Mus musculus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:MGI; .
GOGO:0001758; F:retinal dehydrogenase activity; IEA:EC; .
GOGO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:MGI; .
GOGO:0002072; P:optic cup morphogenesis involved in camera-type eye development; IGI:MGI; .
GOGO:0043065; P:positive regulation of apoptosis; IGI:MGI; .
GOGO:0042493; P:response to drug; IDA:MGI; .
GOGO:0042572; P:retinol metabolic process; IMP:MGI; .
InterProIPR016161; Ald_DH/histidinol_DH; .
InterProIPR016163; Ald_DH_C; .
InterProIPR016160; Ald_DH_CS; .
InterProIPR016162; Ald_DH_N; .
InterProIPR015590; Aldehyde_DH_dom; .
Gene3DG3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1; .
Gene3DG3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1; .
PfamPF00171; Aldedh; 1; .
SUPFAMSSF53720; Aldehyde_DH/Histidinol_DH; 1; .
PROSITEPS00070; ALDEHYDE_DEHYDR_CYS; 1; .
PROSITEPS00687; ALDEHYDE_DEHYDR_GLU; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server