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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P28072




SWISS-2DPAGE:  P28072


P28072


General information about the entry
View entry in simple text format
Entry namePSB6_HUMAN
Primary accession numberP28072
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 13)
Name and origin of the protein
DescriptionRecName: Full=Proteasome subunit beta type-6; EC=3.4.25.1; AltName: Full=Macropain delta chain; AltName: Full=Multicatalytic endopeptidase complex delta chain; AltName: Full=Proteasome delta chain; AltName: Full=Proteasome subunit Y; Flags: Precursor;.
Gene nameName=PSMB6
Synonyms=LMPY, Y
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=96007935; PubMed=7498158; [NCBI, ExPASy, EBI, Israel, Japan]
Gravel P., Sanchez J.-C., Walzer C., Golaz O., Hochstrasser D.F., Balant L.P., Hughes G.J., Garcia-Sevilla J., Guimon J.
''''''Human blood platelet protein map established by two-dimensional polyacrylamide gel electrophoresis'';'';''
Electrophoresis 16(1):1152-1159(1995)
[2]   MAPPING ON GEL
MEDLINE=94147970; PubMed=8313871; [NCBI, ExPASy, EBI, Israel, Japan]
Golaz O., Hughes G.J., Frutiger S., Paquet N., Bairoch A., Pasquali C., Sanchez J.-C., Tissot J.-D., Appel R.D., Walzer C., Balant L.P., Hochstrasser D.F.
''''''Plasma and red blood cell protein maps: update 1993'';'';''
Electrophoresis 14(1):1223-1231(1993)
[3]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_HUMAN {Platelet}
Homo sapiens (Human)
Tissue: Platelet
PLATELET_HUMAN
  map experimental info
  protein estimated location
 
PLATELET_HUMAN

MAP LOCATIONS:
pI=4.88; Mw=23182

MAPPING (identification):
MATCHING WITH THE RBC MASTER GEL [1].



RBC_HUMAN {Red blood cells}
Homo sapiens (Human)
Tissue: Erythrocyte
RBC_HUMAN
  map experimental info
  protein estimated location
 
RBC_HUMAN

MAP LOCATIONS:
pI=4.90; Mw=22700

MAPPING (identification):
MICROSEQUENCING [2].



U937_HUMAN {Macrophage Like Cell Line}
Homo sapiens (Human)
Tissue: Histiocytic lymphoma
U937_HUMAN
  map experimental info
  protein estimated location
 
U937_HUMAN

MAP LOCATIONS:
pI=4.90; Mw=22748

MAPPING (identification):
MATCHING WITH THE LIVER MASTER GEL [3].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP28072.
PHCI-2DPAGEP28072; PSB6_HUMAN.
Siena-2DPAGEP28072; PSB6_HUMAN.
UniProtKB/Swiss-ProtP28072; PSB6_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePSB6_HUMAN
Primary accession numberP28072
Secondary accession number(s) Q96J55
Sequence was last modified on May 10, 2002 (version 4)
Annotations were last modified on October 19, 2011 (version 129)
Name and origin of the protein
DescriptionRecName: Full=Proteasome subunit beta type-6; EC=3.4.25.1; AltName: Full=Macropain delta chain; AltName: Full=Multicatalytic endopeptidase complex delta chain; AltName: Full=Proteasome delta chain; AltName: Full=Proteasome subunit Y; Flags: Precursor;
Gene nameName=PSMB6
Synonyms=LMPY, Y
Encoded onName=PSMB6; Synonyms=LMPY, Y
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Hydrolase; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD29012; BAA06098.1; -; mRNA
EMBLBC000835; AAH00835.1; -; mRNA
EMBLX61971; CAA43963.1; -; mRNA
IPIIPI00000811; -; .
PIRB54589; B54589; .
PIRS17522; S17522; .
RefSeqNP_002789.1; NM_002798.1; .
UniGeneHs.77060; -; .
ProteinModelPortalP28072; -; .
SMRP28072; 35-236; .
IntActP28072; 6; .
MINTMINT-5004163; -; .
STRINGP28072; -; .
PhosphoSiteP28072; -; .
SWISS-2DPAGEP28072; -; .
OGPP28072; -; .
PHCI-2DPAGEP28072; -; .
PeptideAtlasP28072; -; .
PRIDEP28072; -; .
EnsemblENST00000270586; ENSP00000270586; ENSG00000142507; .
GeneID5694; -; .
KEGGhsa:5694; -; .
UCSCuc002fzb.1; human; .
CTD5694; -; .
GeneCardsGC17P004587; -; .
H-InvDBHIX0202476; -; .
HGNCHGNC:9543; PSMB6; .
HPAHPA023312; -; .
MIM600307; gene; .
neXtProtNX_P28072; -; .
PharmGKBPA33888; -; .
eggNOGprNOG16286; -; .
HOGENOMHBG314521; -; .
HOVERGENHBG000123; -; .
InParanoidP28072; -; .
OMAGTSIMAV; -; .
OrthoDBEOG40CHHX; -; .
PhylomeDBP28072; -; .
ReactomeREACT_11045; Signaling by Wnt; .
ReactomeREACT_13; Metabolism of amino acids and derivatives; .
ReactomeREACT_13505; Proteasome mediated degradation of PAK-2p34; .
ReactomeREACT_152; Cell Cycle; Mitotic; .
ReactomeREACT_1538; Cell Cycle Checkpoints; .
ReactomeREACT_21257; Metabolism of RNA; .
ReactomeREACT_383; DNA Replication; .
ReactomeREACT_578; Apoptosis; .
ReactomeREACT_6185; HIV Infection; .
ReactomeREACT_6850; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; .
ReactomeREACT_6900; Immune System; .
NextBio22118; -; .
ArrayExpressP28072; -; .
BgeeP28072; -; .
CleanExHS_PSMB6; -; .
GenevestigatorP28072; -; .
GermOnlineENSG00000142507; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0005839; C:proteasome core complex; NAS:UniProtKB; .
GOGO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW; .
GOGO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; .
GOGO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome; .
GOGO:0006915; P:apoptosis; TAS:Reactome; .
GOGO:0006977; P:DNA damage response; signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome
GOGO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome; .
GOGO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; .
GOGO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome; .
GOGO:0016071; P:mRNA metabolic process; TAS:Reactome; .
GOGO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; .
GOGO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; .
GOGO:0000209; P:protein polyubiquitination; TAS:Reactome; .
GOGO:0042981; P:regulation of apoptosis; TAS:Reactome; .
GOGO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; .
GOGO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome; .
GOGO:0016032; P:viral reproduction; TAS:Reactome; .
InterProIPR000243; Pept_T1A_subB; .
InterProIPR016050; Proteasome_bsu_CS; .
InterProIPR001353; Proteasome_sua/b; .
InterProIPR023333; Proteasome_suB-type; .
PfamPF00227; Proteasome; 1; .
PRINTSPR00141; PROTEASOME; .
PROSITEPS00854; PROTEASOME_B_1; 1; .
PROSITEPS51476; PROTEASOME_B_2; 1; .



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