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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P31947




SWISS-2DPAGE:  P31947


P31947


General information about the entry
View entry in simple text format
Entry name1433S_HUMAN
Primary accession numberP31947
integrated into SWISS-2DPAGE on January 15, 1999 (release 9)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=14-3-3 protein sigma; AltName: Full=Epithelial cell marker protein 1; AltName: Full=Stratifin;.
Gene nameName=SFN
Synonyms=HME1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=4.60; Mw=26759  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP31947.
Siena-2DPAGEP31947; 1433S_HUMAN.
UniProtKB/Swiss-ProtP31947; 1433S_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry name1433S_HUMAN
Primary accession numberP31947
Secondary accession number(s) Q6FH30 Q6FH51 Q96DH0
Sequence was last modified on July 1, 1993 (version 1)
Annotations were last modified on September 21, 2011 (version 121)
Name and origin of the protein
DescriptionRecName: Full=14-3-3 protein sigma; AltName: Full=Epithelial cell marker protein 1; AltName: Full=Stratifin;
Gene nameName=SFN
Synonyms=HME1
Encoded onName=SFN; Synonyms=HME1
Keywords3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Secreted.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM93010; AAA59546.1; -; mRNA
EMBLX57348; CAA40623.1; -; mRNA
EMBLAF029081; AAC52029.1; -; Genomic_DNA
EMBLAF029082; AAC52030.1; -; mRNA
EMBLCR541905; CAG46703.1; -; mRNA
EMBLCR541926; CAG46724.1; -; mRNA
EMBLAL034380; CAB92118.1; -; Genomic_DNA
EMBLBC000329; AAH00329.1; -; mRNA
EMBLBC000995; AAH00995.1; -; mRNA
EMBLBC001550; AAH01550.1; -; mRNA
EMBLBC002995; AAH02995.1; -; mRNA
EMBLBC023552; AAH23552.1; -; mRNA
IPIIPI00013890; -; .
IPIIPI00411765; -; .
PIRS34753; S34753; .
PIRS38956; S38956; .
RefSeqNP_006133.1; NM_006142.3; .
UniGeneHs.523718; -; .
PDB1YWT; X-ray; 2.40 A; A/B=1-248
PDB1YZ5; X-ray; 2.80 A; A/B=1-248
PDB3IQJ; X-ray; 1.15 A; A=1-231
PDB3IQU; X-ray; 1.05 A; A=1-231
PDB3IQV; X-ray; 1.20 A; A=1-231
PDB3LW1; X-ray; 1.28 A; A=1-248
PDB3MHR; X-ray; 1.15 A; A=1-231
PDB3O8I; X-ray; 2.00 A; A=1-231
PDBsum1YWT; -; .
PDBsum1YZ5; -; .
PDBsum3IQJ; -; .
PDBsum3IQU; -; .
PDBsum3IQV; -; .
PDBsum3LW1; -; .
PDBsum3MHR; -; .
PDBsum3O8I; -; .
ProteinModelPortalP31947; -; .
SMRP31947; 1-231; .
DIPDIP-29861N; -; .
IntActP31947; 21; .
MINTMINT-108060; -; .
STRINGP31947; -; .
PhosphoSiteP31947; -; .
SWISS-2DPAGEP31947; -; .
Aarhus/Ghent-2DPAGE9109; IEF; .
Cornea-2DPAGEP31947; -; .
OGPP31947; -; .
PeptideAtlasP31947; -; .
PRIDEP31947; -; .
EnsemblENST00000339276; ENSP00000340989; ENSG00000175793; .
GeneID2810; -; .
KEGGhsa:2810; -; .
UCSCuc001bnc.1; human; .
CTD2810; -; .
GeneCardsGC01P025443; -; .
H-InvDBHIX0199941; -; .
HGNCHGNC:10773; SFN; .
HPACAB006268; -; .
HPACAB040552; -; .
HPAHPA011105; -; .
MIM601290; gene; .
neXtProtNX_P31947; -; .
PharmGKBPA177; -; .
eggNOGprNOG09142; -; .
GeneTreeENSGT00550000074221; -; .
HOGENOMHBG611720; -; .
HOVERGENHBG050423; -; .
InParanoidP31947; -; .
OMAAFMKSAV; -; .
OrthoDBEOG4XH00X; -; .
PhylomeDBP31947; -; .
Pathway_Interaction_DBa6b1_a6b4_integrin_pathway; a6b1 and a6b4 Integrin signaling; .
Pathway_Interaction_DBpi3kciaktpathway; Class I PI3K signaling events mediated by Akt; .
Pathway_Interaction_DBfoxopathway; FoxO family signaling; .
Pathway_Interaction_DBinsulin_glucose_pathway; Insulin-mediated glucose transport; .
Pathway_Interaction_DBp38_mk2pathway; p38 signaling mediated by MAPKAP kinases; .
Pathway_Interaction_DBnfat_3pathway; Role of Calcineurin-dependent NFAT signaling in lymphocytes; .
Pathway_Interaction_DBpi3kplctrkpathway; Trk receptor signaling mediated by PI3K and PLC-gamma; .
NextBio11071; -; .
ArrayExpressP31947; -; .
BgeeP31947; -; .
CleanExHS_SFN; -; .
GenevestigatorP31947; -; .
GermOnlineENSG00000175793; Homo sapiens; .
GOGO:0005737; C:cytoplasm; IDA:HPA; .
GOGO:0005615; C:extracellular space; TAS:ProtInc; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0019904; F:protein domain specific binding; IEA:InterPro; .
GOGO:0008426; F:protein kinase C inhibitor activity; TAS:ProtInc; .
GOGO:0008630; P:DNA damage response; signal transduction resulting in induction of apoptosis; IDA:HGNC
GOGO:0043154; P:negative regulation of caspase activity; IDA:HGNC; .
GOGO:0001836; P:release of cytochrome c from mitochondria; IDA:HGNC; .
InterProIPR000308; 14-3-3; .
InterProIPR023409; 14-3-3_CS; .
InterProIPR023410; 14-3-3_domain; .
Gene3DG3DSA:1.20.190.20; 14-3-3; 1; .
PANTHERPTHR18860; 14-3-3; 1; .
PfamPF00244; 14-3-3; 1; .
PIRSFPIRSF000868; 14-3-3; 1; .
PRINTSPR00305; 1433ZETA; .
SMARTSM00101; 14_3_3; 1; .
SUPFAMSSF48445; 14-3-3; 1; .
PROSITEPS00796; 1433_1; 1; .
PROSITEPS00797; 1433_2; 1; .



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