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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P35232




SWISS-2DPAGE:  P35232


P35232


General information about the entry
View entry in simple text format
Entry namePHB_HUMAN
Primary accession numberP35232
integrated into SWISS-2DPAGE on January 15, 1999 (release 9)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Prohibitin;.
Gene nameName=PHB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
DLD1_HUMAN
  map experimental info
  protein estimated location
 
DLD1_HUMAN

MAP LOCATIONS:
pI=5.36; Mw=27132  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].



LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=5.40; Mw=26439  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP35232; P35232.
DOSAC-COBS-2DPAGEP35232; PHB_HUMAN.
OGP-WWWP35232.
PMMA-2DPAGEP35232; PHB_HUMAN.
REPRODUCTION-2DPAGEIPI00017334; IPI00017334.
REPRODUCTION-2DPAGEP35232; P35232.
Siena-2DPAGEP35232; PHB_HUMAN.
UCD-2DPAGEP35232; PHB_HUMAN.
UniProtKB/Swiss-ProtP35232; PHB_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry namePHB_HUMAN
Primary accession numberP35232
Secondary accession number(s) Q4VBQ0
Sequence was last modified on February 1, 1994 (version 1)
Annotations were last modified on October 19, 2011 (version 115)
Name and origin of the protein
DescriptionRecName: Full=Prohibitin;
Gene nameName=PHB
Encoded onName=PHB
Keywords3D-structure; Acetylation; Coiled coil; Complete proteome; Direct protein sequencing; DNA synthesis; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Polymorphism; Proto-oncogene; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLS85655; AAB21614.1; -; mRNA
EMBLL14272; AAO18340.1; -; Genomic_DNA
EMBLBT007411; AAP36079.1; -; mRNA
EMBLBC013401; AAH13401.1; -; mRNA
EMBLBC095460; AAH95460.1; -; mRNA
IPIIPI00017334; -; .
PIRI52690; I52690; .
RefSeqNP_002625.1; NM_002634.2; .
UniGeneHs.514303; -; .
PDB1LU7; Model; -; A=1-272
PDBsum1LU7; -; .
ProteinModelPortalP35232; -; .
DIPDIP-24248N; -; .
IntActP35232; 39; .
MINTMINT-1158239; -; .
STRINGP35232; -; .
PhosphoSiteP35232; -; .
SWISS-2DPAGEP35232; -; .
DOSAC-COBS-2DPAGEP35232; -; .
OGPP35232; -; .
PMMA-2DPAGEP35232; -; .
REPRODUCTION-2DPAGEIPI00017334; -; .
REPRODUCTION-2DPAGEP35232; -; .
UCD-2DPAGEP35232; -; .
PeptideAtlasP35232; -; .
PRIDEP35232; -; .
EnsemblENST00000300408; ENSP00000300408; ENSG00000167085; .
GeneID5245; -; .
KEGGhsa:5245; -; .
UCSCuc002iox.1; human; .
CTD5245; -; .
GeneCardsGC17M042846; -; .
H-InvDBHIX0013960; -; .
HGNCHGNC:8912; PHB; .
HPAHPA003280; -; .
MIM176705; gene; .
neXtProtNX_P35232; -; .
eggNOGprNOG19550; -; .
HOGENOMHBG680510; -; .
HOVERGENHBG004457; -; .
InParanoidP35232; -; .
OMAIALEDVS; -; .
OrthoDBEOG4X3H23; -; .
PhylomeDBP35232; -; .
NextBio20266; -; .
ArrayExpressP35232; -; .
BgeeP35232; -; .
CleanExHS_PHB; -; .
GenevestigatorP35232; -; .
GermOnlineENSG00000167085; Homo sapiens; .
GOGO:0005887; C:integral to plasma membrane; IDA:HGNC; .
GOGO:0005743; C:mitochondrial inner membrane; TAS:UniProtKB; .
GOGO:0005654; C:nucleoplasm; IDA:UniProtKB; .
GOGO:0042826; F:histone deacetylase binding; IPI:BHF-UCL; .
GOGO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL; .
GOGO:0071354; P:cellular response to interleukin-6; IDA:BHF-UCL; .
GOGO:0006260; P:DNA replication; IEA:UniProtKB-KW; .
GOGO:0016575; P:histone deacetylation; IDA:UniProtKB; .
GOGO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL; .
GOGO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL; .
GOGO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL; .
GOGO:2000323; P:negative regulation of glucocorticoid receptor signaling pathway; IDA:BHF-UCL; .
GOGO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL; .
GOGO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL; .
GOGO:0045893; P:positive regulation of transcription; DNA-dependent; IDA:UniProtKB
GOGO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL; .
GOGO:0042981; P:regulation of apoptosis; TAS:UniProtKB; .
InterProIPR001107; Band_7; .
InterProIPR000163; Prohibitin; .
PANTHERPTHR23222; Prohibitin; 1; .
PfamPF01145; Band_7; 1; .
PRINTSPR00679; PROHIBITIN; .
SMARTSM00244; PHB; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server