Attention: World-2DPAGE is no longer maintained.

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.

References

[1]	MAPPING ON GEL MEDLINE=96154592; PubMed=8586073; [NCBI, Expasy, EBI, Israel, Japan] Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G. ''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';'' Electrophoresis 16(1):1977-1981(1995)
[2]	MAPPING ON GEL PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan] Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F. ''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';'' Proteomics 1(1):136-163(2001)

2D PAGE maps for identified proteins

How to interpret a protein

BAT_MOUSE {Brown adipose tissue}
Mus musculus (Mouse)
Tissue: Brown adipose tissue

map experimental info
protein estimated location

BAT_MOUSE

MAP LOCATIONS:

SPOT 2D-001PWE:

pI=6.72; Mw=40981

MAPPING (identification):
GEL MATCHING WITH WAT_MOUSE [2].

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver

map experimental info
protein estimated location

LIVER_MOUSE

MAP LOCATIONS:

SPOT 2D-0013M6:

pI=6.58; Mw=43547

[identification data]

SPOT 2D-0013OY:

pI=6.77; Mw=40894

MAPPING (identification):

SPOT 2D-0013M6: Peptide mass fingerprinting [2];
SPOT 2D-0013OY: MATCHING [2] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1].

WAT_MOUSE {White adipose tissue}
Mus musculus (Mouse)
Tissue: White adipose tissue

map experimental info
protein estimated location

WAT_MOUSE

MAP LOCATIONS:

SPOT 2D-001BDL:

pI=6.71; Mw=41280

MAPPING (identification):
MATCHING WITH THE MOUSE LIVER MASTER GEL [2].

Copyright

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).

Cross-references

UniProtKB/Swiss-Prot

P35505; FAAA_MOUSE.

2D PAGE maps for identified proteins

How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry name	FAAA_MOUSE
Primary accession number	P35505
Secondary accession number(s)	Q3TY87 Q9QW65
Sequence was last modified on	July 27, 2011 (version 2)
Annotations were last modified on	October 19, 2011 (version 100)
Name and origin of the protein
Description	RecName: Full=Fumarylacetoacetase; Short=FAA; EC=3.7.1.2; AltName: Full=Beta-diketonase; AltName: Full=Fumarylacetoacetate hydrolase;
Gene name	Name=Fah
Encoded on	Name=Fah
Keywords	3D-structure; Acetylation; Calcium; Complete proteome; Hydrolase; Magnesium; Metal-binding; Phenylalanine catabolism; Reference proteome; Tyrosine catabolism.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	M84145; AAA37591.1; -; mRNA
EMBL	Z11774; CAA77819.1; -; mRNA
EMBL	AK143759; BAE25527.1; -; mRNA
EMBL	AK158808; BAE34676.1; -; mRNA
EMBL	BC010767; AAH10767.1; -; mRNA
IPI	IPI00310035; -; .
PIR	A40219; A40219; .
PIR	A56825; A56825; .
RefSeq	NP_034306.2; NM_010176.4; .
UniGene	Mm.3798; -; .
PDB	1HYO; X-ray; 1.30 A; A/B=1-419
PDB	1QCN; X-ray; 1.90 A; A/B=1-419
PDB	1QCO; X-ray; 1.90 A; A/B=1-419
PDB	1QQJ; X-ray; 1.55 A; A/B=1-419
PDB	2HZY; X-ray; 1.35 A; A/B=1-419
PDBsum	1HYO; -; .
PDBsum	1QCN; -; .
PDBsum	1QCO; -; .
PDBsum	1QQJ; -; .
PDBsum	2HZY; -; .
ProteinModelPortal	P35505; -; .
IntAct	P35505; 1; .
STRING	P35505; -; .
PhosphoSite	P35505; -; .
SWISS-2DPAGE	P35505; -; .
PRIDE	P35505; -; .
Ensembl	ENSMUST00000032865; ENSMUSP00000032865; ENSMUSG00000030630; .
GeneID	14085; -; .
NMPDR	fig\|10090.3.peg.16842; -; .
MGI	MGI:95482; Fah; .
eggNOG	roNOG15538; -; .
GeneTree	ENSGT00390000008646; -; .
HOGENOM	HBG289935; -; .
HOVERGEN	HBG001919; -; .
InParanoid	P35505; -; .
OrthoDB	EOG4Q2DFM; -; .
NextBio	285108; -; .
ArrayExpress	P35505; -; .
Bgee	P35505; -; .
CleanEx	MM_FAH; -; .
Genevestigator	P35505; -; .
GermOnline	ENSMUSG00000030630; Mus musculus; .
GO	GO:0004334; F:fumarylacetoacetase activity; IMP:MGI; .
GO	GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GO	GO:0006527; P:arginine catabolic process; IMP:MGI; .
GO	GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW; .
GO	GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW; .
InterPro	IPR005959; Fumarylacetoacetase; .
InterPro	IPR002529; Fumarylacetoacetase_C; .
InterPro	IPR011234; Fumarylacetoacetase_C-rel; .
InterPro	IPR015377; Fumarylacetoacetase_N; .
Gene3D	G3DSA:3.90.850.10; Fumarylacetoacetase_C-rel; 1; .
Gene3D	G3DSA:2.30.30.230; Fumarylacetoacetase_N; 1; .
PANTHER	PTHR11820:SF1; Fum_ac_acetase; 1; .
Pfam	PF09298; DUF1969; 1; .
Pfam	PF01557; FAA_hydrolase; 1; .
SUPFAM	SSF56529; Fumarylacetoacetase_C-rel; 1; .
SUPFAM	SSF63433; Fumarylacetoacetase_N; 1; .
TIGRFAMs	TIGR01266; Fum_ac_acetase; 1; .

SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server