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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P48643




SWISS-2DPAGE:  P48643


P48643


General information about the entry
View entry in simple text format
Entry nameTCPE_HUMAN
Primary accession numberP48643
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 2)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=T-complex protein 1 subunit epsilon; Short=TCP-1-epsilon; AltName: Full=CCT-epsilon;.
Gene nameName=CCT5
Synonyms=CCTE, KIAA0098
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
[2]   MAPPING ON GEL
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
Comments
  • SUBUNIT: HETERO-OLIGOMERIC COMPLEX OF ABOUT 850 TO 900 kDa THAT FORMS TWO STACKED RINGS, 12 TO 16 NM IN DIAMETER
2D PAGE maps for identified proteins
How to interpret a protein

LYMPHOCYTE_HUMAN {Lymphocytes}
Homo sapiens (Human)
Tissue: Lymphocyte
LYMPHOCYTE_HUMAN
  map experimental info
  protein estimated location
 
LYMPHOCYTE_HUMAN

MAP LOCATIONS:
pI=5.40; Mw=43724  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [2].



NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=5.67; Mw=61221  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
OGP-WWWP48643.
PHCI-2DPAGEP48643.
REPRODUCTION-2DPAGEIPI00010720; IPI00010720.
Siena-2DPAGEP48643; TCPE_HUMAN.
UniProtKB/Swiss-ProtP48643; TCPE_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameTCPE_HUMAN
Primary accession numberP48643
Secondary accession number(s) A8JZY8
Sequence was last modified on February 1, 1996 (version 1)
Annotations were last modified on September 21, 2011 (version 118)
Name and origin of the protein
DescriptionRecName: Full=T-complex protein 1 subunit epsilon; Short=TCP-1-epsilon; AltName: Full=CCT-epsilon;
Gene nameName=CCT5
Synonyms=CCTE, KIAA0098
Encoded onName=CCT5; Synonyms=CCTE, KIAA0098
KeywordsAcetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; Neuropathy; Nucleotide-binding; Polymorphism; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD43950; BAA07894.2; ALT_INIT; mRNA
EMBLAK289353; BAF82042.1; -; mRNA
EMBLCH471102; EAX08072.1; -; Genomic_DNA
EMBLBC006543; AAH06543.1; -; mRNA
EMBLBC035499; AAH35499.1; -; mRNA
IPIIPI00010720; -; .
RefSeqNP_036205.1; NM_012073.3; .
UniGeneHs.725167; -; .
ProteinModelPortalP48643; -; .
SMRP48643; 16-537; .
IntActP48643; 29; .
MINTMINT-1154718; -; .
STRINGP48643; -; .
PhosphoSiteP48643; -; .
SWISS-2DPAGEP48643; -; .
OGPP48643; -; .
PHCI-2DPAGEP48643; -; .
REPRODUCTION-2DPAGEIPI00010720; -; .
PeptideAtlasP48643; -; .
PRIDEP48643; -; .
EnsemblENST00000280326; ENSP00000280326; ENSG00000150753; .
GeneID22948; -; .
KEGGhsa:22948; -; .
UCSCuc003jeq.1; human; .
CTD22948; -; .
GeneCardsGC05P010236; -; .
H-InvDBHIX0004744; -; .
H-InvDBHIX0120997; -; .
HGNCHGNC:1618; CCT5; .
HPACAB006271; -; .
HPAHPA002238; -; .
HPAHPA005958; -; .
MIM256840; phenotype; .
MIM610150; gene; .
neXtProtNX_P48643; -; .
Orphanet2683; Sensory neuropathy - spastic paraplegia; .
PharmGKBPA26182; -; .
eggNOGprNOG05593; -; .
HOGENOMHBG497503; -; .
HOVERGENHBG106507; -; .
InParanoidP48643; -; .
OMAEYGRPFI; -; .
OrthoDBEOG40P46J; -; .
PhylomeDBP48643; -; .
ReactomeREACT_17015; Metabolism of proteins; .
NextBio43711; -; .
ArrayExpressP48643; -; .
BgeeP48643; -; .
CleanExHS_CCT5; -; .
GenevestigatorP48643; -; .
GermOnlineENSG00000150753; Homo sapiens; .
GOGO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0051082; F:unfolded protein binding; IEA:InterPro; .
GOGO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome; .
GOGO:0009615; P:response to virus; IEP:UniProtKB; .
InterProIPR012718; Chap_CCT_epsi; .
InterProIPR017998; Chaperone_TCP-1; .
InterProIPR002194; Chaperonin_TCP-1_CS; .
InterProIPR002423; Cpn60/TCP-1; .
PANTHERPTHR11353:SF25; Chap_CCT_epsi; 1; .
PANTHERPTHR11353; Cpn60/TCP-1; 1; .
PfamPF00118; Cpn60_TCP1; 1; .
PRINTSPR00304; TCOMPLEXTCP1; .
SUPFAMSSF48592; GroEL-ATPase; 1; .
TIGRFAMsTIGR02343; Chap_CCT_epsi; 1; .
PROSITEPS00750; TCP1_1; 1; .
PROSITEPS00751; TCP1_2; 1; .
PROSITEPS00995; TCP1_3; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server