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SWISS-2DPAGE

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It will be discontinued on 31-May-2024.

Swiss-2DPAGE data (text records and image files) will continue to be available from https://ftp.expasy.org/databases/swiss-2dpage/.


SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P50136




SWISS-2DPAGE:  P50136


P50136


General information about the entry
View entry in simple text format
Entry nameODBA_MOUSE
Primary accession numberP50136
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onMay 15, 2003 (version 2)
General Annotations were last modified on May 19, 2011 (version 12)
Name and origin of the protein
DescriptionRecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; EC=1.2.4.4; AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; Short=BCKDE1A; Short=BCKDH E1-alpha; Flags: Precursor;.
Gene nameName=Bckdha
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.95; Mw=44527  [identification data]
pI=6.31; Mw=43426

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP50136; ODBA_MOUSE.
World-2DPAGE RepositoryP50136; ODBA_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameODBA_MOUSE
Primary accession numberP50136
Sequence was last modified on October 1, 1996 (version 1)
Annotations were last modified on September 21, 2011 (version 97)
Name and origin of the protein
DescriptionRecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; EC=1.2.4.4; AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; Short=BCKDE1A; Short=BCKDH E1-alpha; Flags: Precursor;
Gene nameName=Bckdha
Encoded onName=Bckdha
KeywordsComplete proteome; Metal-binding; Mitochondrion; Oxidoreductase; Phosphoprotein; Potassium; Reference proteome; Thiamine pyrophosphate; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLL47335; AAB38422.1; -; mRNA
IPIIPI00331555; -; .
PIRS71881; S71881; .
UniGeneMm.25848; -; .
ProteinModelPortalP50136; -; .
SMRP50136; 48-442; .
STRINGP50136; -; .
PhosphoSiteP50136; -; .
SWISS-2DPAGEP50136; -; .
PRIDEP50136; -; .
MGIMGI:107701; Bckdha; .
eggNOGroNOG08618; -; .
HOVERGENHBG002459; -; .
InParanoidP50136; -; .
OrthoDBEOG4RR6JR; -; .
ArrayExpressP50136; -; .
BgeeP50136; -; .
GenevestigatorP50136; -; .
GermOnlineENSMUSG00000060376; Mus musculus; .
GOGO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC; .
GOGO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; IEA:EC; .
GOGO:0003826; F:alpha-ketoacid dehydrogenase activity; ISS:HGNC; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC; .
InterProIPR001017; DH_E1; .
PfamPF00676; E1_dh; 1; .



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SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server